| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0373879 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0256344 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.025526 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0246184 |
| CCNL1 | cyclin L1 | 0.0242884 |
| OGA | O-GlcNAcase | 0.023498 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0213022 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0204485 |
| NEK7 | NIMA-related kinase 7 | 0.0202522 |
| ITGA6 | integrin, alpha 6 | 0.0195404 |
| GDA | guanine deaminase | 0.0188713 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0183661 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0178025 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0170246 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0169227 |
| TUFT1 | tuftelin 1 | 0.0162245 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0161133 |
| HPCAL1 | hippocalcin-like 1 | 0.0159904 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.015633 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0148473 |
| TOP1 | topoisomerase (DNA) I | 0.0144991 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0143698 |
| MYO6 | myosin VI | 0.0143073 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.013842 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0136575 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0136389 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0132765 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0129861 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0129211 |
| ANLN | anillin, actin binding protein | 0.0128391 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0127891 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.012558 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0125448 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0123317 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0122632 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0121997 |
| QKI | QKI, KH domain containing, RNA binding | 0.0116225 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0115663 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0113957 |
| CERT1 | ceramide transporter 1 | 0.0113229 |
| RPL4 | ribosomal protein L4 | 0.0112106 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0110537 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0108026 |
| MKI67 | marker of proliferation Ki-67 | 0.0107858 |
| NPTN | neuroplastin | 0.0107479 |
| VRK2 | vaccinia related kinase 2 | 0.0106818 |
| CAPRIN2 | caprin family member 2 | 0.0106317 |
| RBM39 | RNA binding motif protein 39 | 0.0105797 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0104016 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0103744 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0103437 |
| VCL | vinculin | 0.0103241 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0102485 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0101326 |
| ACTG1 | actin gamma 1 | 0.0100991 |
| KCMF1 | potassium channel modulatory factor 1 | 0.010098 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0100208 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0100194 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.00990049 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.00979279 |
| EPCAM | epithelial cell adhesion molecule | 0.00972781 |
| TMEM164 | transmembrane protein 164 | 0.00963393 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.00961158 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0093857 |
| PLEC | plectin | 0.00937311 |
| MEMO1 | mediator of cell motility 1 | 0.00936957 |
| ECT2 | epithelial cell transforming 2 | 0.00935355 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.00932013 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00915246 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.00913558 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00908018 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.00899125 |
| TRIM36 | tripartite motif containing 36 | 0.00898823 |
| AFDN | afadin, adherens junction formation factor | 0.00896158 |
| DIAPH3 | diaphanous-related formin 3 | 0.00892388 |
| TPD52 | tumor protein D52 | 0.00881273 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00864508 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00861654 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0085962 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.00857246 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00856406 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.00854417 |
| RYK | receptor-like tyrosine kinase | 0.00851632 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.00851134 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.00850722 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0084641 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.00844647 |
| MEF2A | myocyte enhancer factor 2A | 0.0084366 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.00843654 |
| CD47 | CD47 molecule | 0.00840517 |
| DENND3 | DENN/MADD domain containing 3 | 0.00839818 |
| ZNF292 | zinc finger protein 292 | 0.00836197 |
| AREG | amphiregulin | 0.00824545 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00820768 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.00813302 |
| SDC4 | syndecan 4 | 0.00809085 |
| CENPF | centromere protein F, 350/400kDa | 0.0080639 |
| OLA1 | Obg-like ATPase 1 | 0.0080528 |
| USP12 | ubiquitin specific peptidase 12 | 0.0079183 |
| YTHDC1 | YTH domain containing 1 | 0.00787917 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.193795 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.186354 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.170111 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.156492 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.126897 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.122088 |
| TMSB10 | thymosin beta 10 | -0.110537 |
| LAMB3 | laminin, beta 3 | -0.109476 |
| TXNIP | thioredoxin interacting protein | -0.0985547 |
| EGFR | epidermal growth factor receptor | -0.0920909 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0848754 |
| FLNB | filamin B, beta | -0.0838993 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0791855 |
| NDRG1 | N-myc downstream regulated 1 | -0.0778461 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0739074 |
| VIM | vimentin | -0.0719462 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0708058 |
| TXNRD1 | thioredoxin reductase 1 | -0.0664706 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0658968 |
| EZR | ezrin | -0.0653855 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.063378 |
| KLK10 | kallikrein-related peptidase 10 | -0.06222 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0614335 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0596986 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0558239 |
| EFNA5 | ephrin-A5 | -0.0545173 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0539161 |
| CLMP | CXADR-like membrane protein | -0.0538427 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0538259 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0523031 |
| TPM4 | tropomyosin 4 | -0.0519129 |
| UBC | ubiquitin C | -0.0515657 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0499728 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0494132 |
| MXD1 | MAX dimerization protein 1 | -0.0491587 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0484295 |
| HMGA1 | high mobility group AT-hook 1 | -0.0476691 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0474096 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0469448 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0468869 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0460333 |
| TRRAP | transformation/transcription domain-associated protein | -0.0458926 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0449067 |
| MCL1 | myeloid cell leukemia 1 | -0.0448755 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0440443 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0439832 |
| VCAN | versican | -0.0432939 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0432363 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0429073 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0428307 |
| B2M | beta-2-microglobulin | -0.0425794 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0421913 |
| MUC17 | mucin 17, cell surface associated | -0.0421513 |
| FERMT1 | fermitin family member 1 | -0.0420461 |
| LMO7 | LIM domain 7 | -0.0418866 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0413925 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0407382 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0404465 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0401715 |
| RIOK3 | RIO kinase 3 | -0.0401426 |
| CDCP1 | CUB domain containing protein 1 | -0.0400618 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.039074 |
| SVIL | supervillin | -0.0390734 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0385728 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0381709 |
| FAM3C | family with sequence similarity 3, member C | -0.0380486 |
| EGR1 | early growth response 1 | -0.0378914 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0378758 |
| ARF4 | ADP-ribosylation factor 4 | -0.0377126 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0376629 |
| DIAPH1 | diaphanous-related formin 1 | -0.0375005 |
| CALU | calumenin | -0.0366473 |
| RRBP1 | ribosome binding protein 1 | -0.0361225 |
| FTL | ferritin, light polypeptide | -0.0359773 |
| UPP1 | uridine phosphorylase 1 | -0.0359178 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0357802 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.035594 |
| EXT1 | exostosin glycosyltransferase 1 | -0.035166 |
| AK1 | adenylate kinase 1 | -0.0346702 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0343346 |
| PRSS3 | protease, serine, 3 | -0.0341371 |
| DIAPH2 | diaphanous-related formin 2 | -0.0341144 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.0334068 |
| OSMR | oncostatin M receptor | -0.0326906 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0318955 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0314768 |
| PGK1 | phosphoglycerate kinase 1 | -0.03144 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0314109 |
| HMGA2 | high mobility group AT-hook 2 | -0.0311481 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0311107 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0310894 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0306406 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0304911 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0304025 |
| RPS21 | ribosomal protein S21 | -0.0302252 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0293314 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0292639 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0289164 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0288569 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0288318 |
