| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VMP1 | vacuole membrane protein 1 | 0.075722 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0692846 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0622229 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0570583 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0507943 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0489176 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0437474 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0428588 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0379877 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0359021 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0350312 |
| ASPH | aspartate beta-hydroxylase | 0.0310899 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0290098 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.0286558 |
| S100A8 | S100 calcium binding protein A8 | 0.0284016 |
| YPEL2 | yippee-like 2 (Drosophila) | 0.0280092 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.026958 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0262726 |
| FADS2 | fatty acid desaturase 2 | 0.0254723 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0249612 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0244493 |
| TPM3 | tropomyosin 3 | 0.0236977 |
| SMYD3 | SET and MYND domain containing 3 | 0.023376 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0232639 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0231255 |
| TC2N | tandem C2 domains, nuclear | 0.0228862 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0218933 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0214328 |
| KRT19 | keratin 19, type I | 0.0210351 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0209979 |
| TMEM45B | transmembrane protein 45B | 0.0209688 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | 0.020806 |
| DST | dystonin | 0.0203834 |
| APP | amyloid beta (A4) precursor protein | 0.0203751 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0203514 |
| LDHA | lactate dehydrogenase A | 0.0201964 |
| TXNRD1 | thioredoxin reductase 1 | 0.0198996 |
| SDC4 | syndecan 4 | 0.0197468 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0193758 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0191924 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.01901 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0188442 |
| CCNL1 | cyclin L1 | 0.01845 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0180623 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0180368 |
| PTK2 | protein tyrosine kinase 2 | 0.0179733 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0178817 |
| ZNF652 | zinc finger protein 652 | 0.0178129 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.0176831 |
| DSPP | dentin sialophosphoprotein | 0.0175034 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.0173678 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0171893 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0171882 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0171384 |
| CD164 | CD164 molecule, sialomucin | 0.0171132 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0170017 |
| OSMR | oncostatin M receptor | 0.016547 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0162538 |
| TMC5 | transmembrane channel-like 5 | 0.0161989 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0160674 |
| GDPD1 | glycerophosphodiester phosphodiesterase domain containing 1 | 0.015996 |
| ATP9A | ATPase, class II, type 9A | 0.0157424 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0157067 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0151326 |
| ATXN1 | ataxin 1 | 0.0150448 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0150141 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0149002 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0147114 |
| EZR | ezrin | 0.0146513 |
| KRT8 | keratin 8, type II | 0.0146157 |
| MYO1B | myosin IB | 0.0146038 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.014528 |
| SRPK2 | SRSF protein kinase 2 | 0.0143145 |
| MAP1B | microtubule-associated protein 1B | 0.0141598 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0141392 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.0141068 |
| VEGFA | vascular endothelial growth factor A | 0.0141008 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0140511 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0139866 |
| SERINC3 | serine incorporator 3 | 0.0138038 |
| PGK1 | phosphoglycerate kinase 1 | 0.0135198 |
| ABHD17C | abhydrolase domain containing 17C | 0.0134139 |
| EGFR | epidermal growth factor receptor | 0.0133146 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0133034 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0132843 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0132583 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0132319 |
| MLPH | melanophilin | 0.0131724 |
| PLEC | plectin | 0.0130382 |
| PANK3 | pantothenate kinase 3 | 0.0129892 |
| S100A14 | S100 calcium binding protein A14 | 0.0129059 |
| ANXA2 | annexin A2 | 0.0128832 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0128289 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0128286 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0127961 |
| NTN4 | netrin 4 | 0.0126624 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0126047 |
| DUSP4 | dual specificity phosphatase 4 | 0.0125184 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0124299 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0124129 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.125573 |
| RPL19 | ribosomal protein L19 | -0.1094 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0466953 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0374726 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0321415 |
| ACTG1 | actin gamma 1 | -0.0320294 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0288996 |
| SP100 | SP100 nuclear antigen | -0.0252879 |
| DTNA | dystrobrevin, alpha | -0.0246073 |
| RPL35A | ribosomal protein L35a | -0.0244284 |
| INTS6 | integrator complex subunit 6 | -0.0238407 |
| PTMA | prothymosin, alpha | -0.0222813 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0215141 |
| RPS6 | ribosomal protein S6 | -0.0211086 |
| RPS8 | ribosomal protein S8 | -0.0208951 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0193488 |
| RPL12 | ribosomal protein L12 | -0.0191162 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0191095 |
| RPL34 | ribosomal protein L34 | -0.0186917 |
| CDK12 | cyclin-dependent kinase 12 | -0.0183264 |
| RPL37A | ribosomal protein L37a | -0.0180052 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0178162 |
| SQSTM1 | sequestosome 1 | -0.017246 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0167018 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0164505 |
| HMGB1 | high mobility group box 1 | -0.0159154 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0156495 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0146207 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0145843 |
| RPS24 | ribosomal protein S24 | -0.0142794 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0140713 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0139032 |
| PLSCR2 | phospholipid scramblase 2 | -0.0138778 |
| ZNF292 | zinc finger protein 292 | -0.0137784 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0136809 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | -0.0136805 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0136678 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0132286 |
| CDK13 | cyclin-dependent kinase 13 | -0.0130612 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0128815 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0127974 |
| TCEA2 | transcription elongation factor A (SII), 2 | -0.0127295 |
| RPS3 | ribosomal protein S3 | -0.0124473 |
| GLCCI1 | glucocorticoid induced 1 | -0.0123537 |
| RPS29 | ribosomal protein S29 | -0.0123004 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0122489 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0119516 |
| RPS19 | ribosomal protein S19 | -0.0118983 |
| PRR11 | proline rich 11 | -0.0118601 |
| RPL35 | ribosomal protein L35 | -0.0118523 |
| PFDN4 | prefoldin subunit 4 | -0.0117919 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0115671 |
| RRBP1 | ribosome binding protein 1 | -0.0115052 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0114328 |
| RPS2 | ribosomal protein S2 | -0.0113922 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0112702 |
| TPD52 | tumor protein D52 | -0.0111393 |
| RACK1 | receptor for activated C kinase 1 | -0.0110386 |
| RPL37 | ribosomal protein L37 | -0.0109024 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0108996 |
| PLSCR1 | phospholipid scramblase 1 | -0.0108991 |
| BRD4 | bromodomain containing 4 | -0.0108548 |
| ADIPOR2 | adiponectin receptor 2 | -0.0108133 |
| SCFD1 | sec1 family domain containing 1 | -0.0107933 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | -0.0107486 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0106858 |
| RPL9 | ribosomal protein L9 | -0.010674 |
| RPL11 | ribosomal protein L11 | -0.0106591 |
| STXBP4 | syntaxin binding protein 4 | -0.0106543 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0106251 |
| USP15 | ubiquitin specific peptidase 15 | -0.0106215 |
| RPLP1 | ribosomal protein, large, P1 | -0.0105505 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0105374 |
| TENM2 | teneurin transmembrane protein 2 | -0.0105373 |
| RPL5 | ribosomal protein L5 | -0.0105045 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0104603 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0104263 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0104025 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0103843 |
| NPR2 | natriuretic peptide receptor 2 | -0.0103554 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0103475 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0102923 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.010292 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0102101 |
| RPL26 | ribosomal protein L26 | -0.0100539 |
| MCU | mitochondrial calcium uniporter | -0.0100267 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.00993294 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00961245 |
| IRF1 | interferon regulatory factor 1 | -0.00953114 |
| FNIP1 | folliculin interacting protein 1 | -0.00945243 |
| SMAD3 | SMAD family member 3 | -0.00943831 |
| YBX1 | Y box binding protein 1 | -0.00941801 |
| GNAS | GNAS complex locus | -0.00936431 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.00931479 |
| UNC13B | unc-13 homolog B (C. elegans) | -0.00922966 |
| RPLP2 | ribosomal protein, large, P2 | -0.00918114 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00917667 |
| MSI2 | musashi RNA-binding protein 2 | -0.00913908 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00912199 |
| RPL32 | ribosomal protein L32 | -0.00911196 |
