| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0703451 |
| VEGFA | vascular endothelial growth factor A | 0.0590395 |
| EGR1 | early growth response 1 | 0.0582242 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0560118 |
| CCNL1 | cyclin L1 | 0.0471096 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0465932 |
| VCL | vinculin | 0.0389013 |
| FMN1 | formin 1 | 0.0387819 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0386239 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0358153 |
| POTEF | POTE ankyrin domain family, member F | 0.0346033 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0345288 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0314323 |
| COPA | coatomer protein complex, subunit alpha | 0.0295016 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0294965 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0292434 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0290331 |
| PI15 | peptidase inhibitor 15 | 0.0265338 |
| MSN | moesin | 0.0263086 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0261514 |
| RAD51B | RAD51 paralog B | 0.0254187 |
| MCL1 | myeloid cell leukemia 1 | 0.0251176 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0251145 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0247884 |
| IER2 | immediate early response 2 | 0.0244871 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0237529 |
| BRD2 | bromodomain containing 2 | 0.0234427 |
| VGF | VGF nerve growth factor inducible | 0.0232927 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.022756 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0225858 |
| TSC22D1 | TSC22 domain family, member 1 | 0.022508 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.022506 |
| GPATCH2L | G patch domain containing 2-like | 0.0224377 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0220614 |
| VMP1 | vacuole membrane protein 1 | 0.0219866 |
| TPM3 | tropomyosin 3 | 0.0216707 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0215321 |
| LAMB1 | laminin, beta 1 | 0.0214756 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0214069 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0212098 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0210996 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0210097 |
| CYTH3 | cytohesin 3 | 0.0205566 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0205115 |
| RPL3 | ribosomal protein L3 | 0.0201255 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0195757 |
| JUN | jun proto-oncogene | 0.0195675 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0188905 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0187843 |
| TPM4 | tropomyosin 4 | 0.0185007 |
| SET | SET nuclear proto-oncogene | 0.0183453 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0183306 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0181165 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0180487 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0179307 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.017885 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0178611 |
| CALD1 | caldesmon 1 | 0.0178434 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.017802 |
| B2M | beta-2-microglobulin | 0.0177345 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0176958 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.017581 |
| HDGF | hepatoma-derived growth factor | 0.0172295 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0170914 |
| BPTF | bromodomain PHD finger transcription factor | 0.016902 |
| AHR | aryl hydrocarbon receptor | 0.0168497 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0168425 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.016599 |
| FTL | ferritin, light polypeptide | 0.0163795 |
| NES | nestin | 0.016363 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0163044 |
| ZNF146 | zinc finger protein 146 | 0.0162335 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0161126 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0160833 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.015846 |
| FNBP4 | formin binding protein 4 | 0.015843 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0157461 |
| SETD5 | SET domain containing 5 | 0.0157265 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0157062 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0156662 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0154887 |
| EHBP1 | EH domain binding protein 1 | 0.0154457 |
| CEP350 | centrosomal protein 350kDa | 0.0152863 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0150219 |
| PNN | pinin, desmosome associated protein | 0.0150172 |
| FOSL1 | FOS-like antigen 1 | 0.0149954 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0149759 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0148585 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0148138 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0145917 |
| RPL21 | ribosomal protein L21 | 0.0145903 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0145779 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0145404 |
| RBM8A | RNA binding motif protein 8A | 0.0145197 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0145063 |
| SERINC3 | serine incorporator 3 | 0.0143478 |
| HLA-A | major histocompatibility complex, class I, A | 0.0143099 |
| TMF1 | TATA element modulatory factor 1 | 0.0142388 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0142292 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.014215 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.36368 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.262763 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.14555 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.112154 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.108143 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0846479 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0775257 |
| TNNC1 | troponin C type 1 (slow) | -0.077091 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0736353 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0711991 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0706091 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0691007 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0672999 |
| FMNL2 | formin-like 2 | -0.0655766 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0613188 |
| VIM | vimentin | -0.0597299 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0582652 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0578319 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0566391 |
| CDC73 | cell division cycle 73 | -0.0565773 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0564944 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0559451 |
| CLMN | calmin (calponin-like, transmembrane) | -0.0535109 |
| IER3 | immediate early response 3 | -0.0533391 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.051765 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0484746 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0465457 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0462174 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0458069 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0437388 |
| ACTG1 | actin gamma 1 | -0.0430546 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0426807 |
| COG5 | component of oligomeric golgi complex 5 | -0.0425845 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0425843 |
| NLGN1 | neuroligin 1 | -0.041657 |
| RRBP1 | ribosome binding protein 1 | -0.0410892 |
| PRELID2 | PRELI domain containing 2 | -0.0410481 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0409775 |
| WDR45B | WD repeat domain 45B | -0.040226 |
| OSMR | oncostatin M receptor | -0.03905 |
| TMEM123 | transmembrane protein 123 | -0.0385161 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0384341 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0383763 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0382885 |
| OGA | O-GlcNAcase | -0.0381913 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0380439 |
| BBX | bobby sox homolog (Drosophila) | -0.037172 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0371101 |
| ATXN1 | ataxin 1 | -0.0370953 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0367414 |
| S100A6 | S100 calcium binding protein A6 | -0.0365483 |
| PGK1 | phosphoglycerate kinase 1 | -0.0362415 |
| GPC6 | glypican 6 | -0.0360171 |
| PTK2 | protein tyrosine kinase 2 | -0.035944 |
| ZNF292 | zinc finger protein 292 | -0.035852 |
| SDC2 | syndecan 2 | -0.0355293 |
| NDRG1 | N-myc downstream regulated 1 | -0.0342892 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0341735 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0340388 |
| CDK14 | cyclin-dependent kinase 14 | -0.0339134 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.0337807 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0333087 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0325879 |
| HELZ | helicase with zinc finger | -0.0322683 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.031787 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0312182 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0306011 |
| NPR2 | natriuretic peptide receptor 2 | -0.0304446 |
| GSN | gelsolin | -0.0303844 |
| VGLL4 | vestigial-like family member 4 | -0.0303392 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0300971 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0294097 |
| GNAS | GNAS complex locus | -0.0292193 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0290661 |
| ANXA5 | annexin A5 | -0.028626 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0285628 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0281186 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.028112 |
| FOXJ3 | forkhead box J3 | -0.0280012 |
| PHF21A | PHD finger protein 21A | -0.0275809 |
| CTTNBP2 | cortactin binding protein 2 | -0.027461 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0274308 |
| SMAD3 | SMAD family member 3 | -0.0271239 |
| FUS | FUS RNA binding protein | -0.0268524 |
| NAV2 | neuron navigator 2 | -0.02672 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0264741 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0263758 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0261619 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0260263 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0253619 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0250213 |
| AHNAK | AHNAK nucleoprotein | -0.0249698 |
| PCDH7 | protocadherin 7 | -0.0248568 |
| OXR1 | oxidation resistance 1 | -0.0247175 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.024698 |
| USP3 | ubiquitin specific peptidase 3 | -0.0246305 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0245039 |
| NHSL1 | NHS-like 1 | -0.0241838 |
| MT2A | metallothionein 2A | -0.024113 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0240641 |
