| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vitamin K4_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.0835887 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0694153 |
| CCNL1 | cyclin L1 | 0.049299 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0398388 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0388749 |
| TGM2 | transglutaminase 2 | 0.0384127 |
| POTEF | POTE ankyrin domain family, member F | 0.0350042 |
| BRD2 | bromodomain containing 2 | 0.0317829 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0316366 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0314606 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0310023 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0308913 |
| NABP1 | nucleic acid binding protein 1 | 0.0297964 |
| MCL1 | myeloid cell leukemia 1 | 0.0288697 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0270962 |
| DST | dystonin | 0.0260201 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0258906 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0248709 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0245681 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0218676 |
| INTS6 | integrator complex subunit 6 | 0.0213485 |
| TPM3 | tropomyosin 3 | 0.0205029 |
| NOTCH2 | notch 2 | 0.0190736 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0188974 |
| VMP1 | vacuole membrane protein 1 | 0.0188775 |
| RUNX1 | runt-related transcription factor 1 | 0.0188232 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0186258 |
| RASAL2 | RAS protein activator like 2 | 0.0185059 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.01831 |
| SEPTIN9 | septin 9 | 0.018087 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0179639 |
| MSN | moesin | 0.01789 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0177476 |
| HDAC9 | histone deacetylase 9 | 0.017672 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.017579 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0174956 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0171431 |
| FOSL2 | FOS-like antigen 2 | 0.0169828 |
| PCBP2 | poly(rC) binding protein 2 | 0.0168484 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0163607 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0158638 |
| BCL2L1 | BCL2-like 1 | 0.0156008 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0155532 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0152458 |
| RPL3 | ribosomal protein L3 | 0.0149605 |
| GPATCH2L | G patch domain containing 2-like | 0.0146398 |
| RAD51B | RAD51 paralog B | 0.0143357 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0142743 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.014254 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0142458 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0140298 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0137927 |
| PNN | pinin, desmosome associated protein | 0.0136002 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0135589 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.013303 |
| TJP1 | tight junction protein 1 | 0.0132527 |
| AGRN | agrin | 0.0131676 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0130948 |
| HDGF | hepatoma-derived growth factor | 0.013005 |
| PRELID2 | PRELI domain containing 2 | 0.0129586 |
| ANXA1 | annexin A1 | 0.0127343 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0125758 |
| DIAPH1 | diaphanous-related formin 1 | 0.0124853 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0123365 |
| HKDC1 | hexokinase domain containing 1 | 0.0122476 |
| STC2 | stanniocalcin 2 | 0.0122433 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0121984 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0121051 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0119837 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0119762 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0117373 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0116153 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0115002 |
| BICC1 | BicC family RNA binding protein 1 | 0.011286 |
| PDLIM5 | PDZ and LIM domain 5 | 0.011161 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0111521 |
| CAPRIN2 | caprin family member 2 | 0.0111022 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0109264 |
| TPM1 | tropomyosin 1 (alpha) | 0.0106999 |
| TUFT1 | tuftelin 1 | 0.0106752 |
| NTN4 | netrin 4 | 0.0105945 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0105864 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0105845 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0105631 |
| SVIL | supervillin | 0.0105545 |
| PCNX4 | pecanex 4 | 0.0105516 |
| DUOX2 | dual oxidase 2 | 0.0104518 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0103405 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0103195 |
| EGR1 | early growth response 1 | 0.0102974 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.010248 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0102164 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0101864 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0101704 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0101419 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0101242 |
| EXOC6B | exocyst complex component 6B | 0.0101199 |
| PAPOLA | poly(A) polymerase alpha | 0.0100456 |
| GPHN | gephyrin | 0.00997181 |
| ACTN1 | actinin, alpha 1 | 0.00989928 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.306449 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.204307 |
| MMP7 | matrix metallopeptidase 7 | -0.165798 |
| LAMB3 | laminin, beta 3 | -0.148079 |
| TMSB10 | thymosin beta 10 | -0.142076 |
| HLA-B | major histocompatibility complex, class I, B | -0.123917 |
| PTMA | prothymosin, alpha | -0.121775 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.118291 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.114922 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.104326 |
| CP | ceruloplasmin (ferroxidase) | -0.10304 |
| KRT19 | keratin 19, type I | -0.0939415 |
| APOL1 | apolipoprotein L, 1 | -0.087191 |
| NDRG1 | N-myc downstream regulated 1 | -0.0862878 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0808036 |
| S100A6 | S100 calcium binding protein A6 | -0.0797384 |
| PGK1 | phosphoglycerate kinase 1 | -0.0781277 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0779413 |
| MT2A | metallothionein 2A | -0.0771035 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0731844 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0722044 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0720039 |
| ACTG1 | actin gamma 1 | -0.0709871 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0706224 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0675023 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0664551 |
| VIM | vimentin | -0.0656612 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0632653 |
| ANXA2 | annexin A2 | -0.0628202 |
| LAMC2 | laminin, gamma 2 | -0.0601171 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0578346 |
| UBC | ubiquitin C | -0.0573046 |
| KLF6 | Kruppel-like factor 6 | -0.0562791 |
| AHNAK | AHNAK nucleoprotein | -0.0543181 |
| S100A10 | S100 calcium binding protein A10 | -0.0538391 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0532095 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0531543 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0522257 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0515664 |
| RPLP1 | ribosomal protein, large, P1 | -0.0511392 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0505065 |
| CSTB | cystatin B (stefin B) | -0.0501785 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0494098 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0494084 |
| RRBP1 | ribosome binding protein 1 | -0.0491979 |
| HLA-A | major histocompatibility complex, class I, A | -0.0483657 |
| RPL35A | ribosomal protein L35a | -0.0479632 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0466218 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0464806 |
| ENO1 | enolase 1, (alpha) | -0.0459115 |
| HLA-E | major histocompatibility complex, class I, E | -0.0450888 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0448444 |
| IER3 | immediate early response 3 | -0.0435448 |
| RPS8 | ribosomal protein S8 | -0.04354 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0431039 |
| TMSB4X | thymosin beta 4, X-linked | -0.0429459 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0404199 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0379292 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0377982 |
| MT1X | metallothionein 1X | -0.0376518 |
| RPL34 | ribosomal protein L34 | -0.0376113 |
| PLAT | plasminogen activator, tissue | -0.0375919 |
| WDR45B | WD repeat domain 45B | -0.0375914 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0373889 |
| RPS24 | ribosomal protein S24 | -0.037082 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0370138 |
| LAMA4 | laminin, alpha 4 | -0.0369237 |
| GNAS | GNAS complex locus | -0.0368081 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0365747 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0357949 |
| CD2AP | CD2-associated protein | -0.0353171 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0352777 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0351011 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0350413 |
| RPL11 | ribosomal protein L11 | -0.0349197 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0340775 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0339594 |
| RPS21 | ribosomal protein S21 | -0.033871 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0330222 |
| DSG2 | desmoglein 2 | -0.0323856 |
| FAM162A | family with sequence similarity 162, member A | -0.0317473 |
| RPS29 | ribosomal protein S29 | -0.0313341 |
| LMNA | lamin A/C | -0.0308646 |
| TPM4 | tropomyosin 4 | -0.0306402 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0303167 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0302126 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0290142 |
| SPAG9 | sperm associated antigen 9 | -0.0287772 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0284911 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0284653 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0283906 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.028369 |
| RPL19 | ribosomal protein L19 | -0.0280406 |
| RPS27A | ribosomal protein S27a | -0.0279439 |
| LCN2 | lipocalin 2 | -0.0277878 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0276299 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0275711 |
| PARD3 | par-3 family cell polarity regulator | -0.0274864 |
| FAM13A | family with sequence similarity 13, member A | -0.0274451 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0271932 |