| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.0784062 |
| MT2A | metallothionein 2A | 0.0736565 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0549586 |
| MSN | moesin | 0.0533695 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0475775 |
| TPM3 | tropomyosin 3 | 0.0372698 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0321016 |
| STK17B | serine/threonine kinase 17b | 0.0309578 |
| GOLGB1 | golgin B1 | 0.0308284 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0303828 |
| TXNIP | thioredoxin interacting protein | 0.0266594 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0262076 |
| B2M | beta-2-microglobulin | 0.0261152 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0254684 |
| ZNF160 | zinc finger protein 160 | 0.0249595 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0243729 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0237669 |
| MYO1B | myosin IB | 0.0236126 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0233857 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.022391 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0220572 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0217354 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0215883 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0212534 |
| MCL1 | myeloid cell leukemia 1 | 0.02059 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0205174 |
| HDAC9 | histone deacetylase 9 | 0.0200006 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.019976 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0199461 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0198942 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0184153 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0181866 |
| ZNF148 | zinc finger protein 148 | 0.0177252 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0174078 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0172273 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0171919 |
| USO1 | USO1 vesicle transport factor | 0.0170271 |
| BPTF | bromodomain PHD finger transcription factor | 0.0165783 |
| ZNF146 | zinc finger protein 146 | 0.0164743 |
| MYADM | myeloid-associated differentiation marker | 0.0163193 |
| ZNF841 | zinc finger protein 841 | 0.0162773 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0162526 |
| MT1X | metallothionein 1X | 0.016217 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0161149 |
| CHRM3 | cholinergic receptor, muscarinic 3 | 0.0159627 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0158889 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 | 0.0157731 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0154205 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0153216 |
| METTL15 | methyltransferase like 15 | 0.0152352 |
| TXNRD1 | thioredoxin reductase 1 | 0.0152253 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0150374 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0148745 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0145832 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0144599 |
| VMP1 | vacuole membrane protein 1 | 0.0144432 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0144353 |
| FOSL2 | FOS-like antigen 2 | 0.0143783 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0142386 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0141598 |
| LIN7C | lin-7 homolog C (C. elegans) | 0.0140461 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | 0.014025 |
| TMEM106B | transmembrane protein 106B | 0.0139866 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0139413 |
| CD47 | CD47 molecule | 0.0139219 |
| SKIL | SKI-like proto-oncogene | 0.0139085 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0139012 |
| PRKCE | protein kinase C, epsilon | 0.0138796 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0138197 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0137973 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0137909 |
| TLN1 | talin 1 | 0.0137838 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.0134122 |
| SRBD1 | S1 RNA binding domain 1 | 0.0132746 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0132083 |
| EFL1 | elongation factor like GTPase 1 | 0.0132058 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0130986 |
| R3HDM2 | R3H domain containing 2 | 0.0129815 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0129316 |
| SMYD3 | SET and MYND domain containing 3 | 0.0129071 |
| C1S | complement component 1, s subcomponent | 0.0128655 |
| CDK19 | cyclin-dependent kinase 19 | 0.0128256 |
| SGCE | sarcoglycan, epsilon | 0.0127826 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0127333 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0126971 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0126969 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0126812 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.012545 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0125285 |
| NUDCD3 | NudC domain containing 3 | 0.0124949 |
| SVIL | supervillin | 0.0124713 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0124131 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0123239 |
| RPL21 | ribosomal protein L21 | 0.0123052 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0123007 |
| SPACA6 | sperm acrosome associated 6 | 0.012257 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.012255 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain | 0.0121805 |
| EXOC4 | exocyst complex component 4 | 0.0121653 |
| RPL35 | ribosomal protein L35 | 0.0121189 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.329152 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.196405 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.109628 |
| COL6A3 | collagen, type VI, alpha 3 | -0.107515 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.103339 |
| FNDC3B | fibronectin type III domain containing 3B | -0.085493 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0852404 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0850244 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0808291 |
| AHNAK | AHNAK nucleoprotein | -0.0675143 |
| CANX | calnexin | -0.0651718 |
| FN1 | fibronectin 1 | -0.0636784 |
| ANXA2 | annexin A2 | -0.0634044 |
| PTMA | prothymosin, alpha | -0.0618875 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0618286 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0614268 |
| TMSB10 | thymosin beta 10 | -0.0596521 |
| SQSTM1 | sequestosome 1 | -0.0595251 |
| KYNU | kynureninase | -0.0578518 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0568136 |
| NAV2 | neuron navigator 2 | -0.0554704 |
| LOX | lysyl oxidase | -0.0542309 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0535538 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0533534 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0531125 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0520103 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0502617 |
| RLF | rearranged L-myc fusion | -0.0491037 |
| EXT1 | exostosin glycosyltransferase 1 | -0.046546 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0463056 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0462248 |
| PGK1 | phosphoglycerate kinase 1 | -0.0460143 |
| NLGN1 | neuroligin 1 | -0.0449625 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0445679 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0440857 |
| CADM1 | cell adhesion molecule 1 | -0.0434827 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0433997 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0430571 |
| MAP1B | microtubule-associated protein 1B | -0.0429945 |
| NDRG1 | N-myc downstream regulated 1 | -0.0425315 |
| GNAS | GNAS complex locus | -0.0416447 |
| TUBB | tubulin, beta class I | -0.0402456 |
| LDHA | lactate dehydrogenase A | -0.0400058 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0395097 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0392261 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0387213 |
| SPAG9 | sperm associated antigen 9 | -0.0382864 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0382758 |
| TNS3 | tensin 3 | -0.0382059 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0371397 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0369921 |
| HDLBP | high density lipoprotein binding protein | -0.0368507 |
| TPM4 | tropomyosin 4 | -0.0367086 |
| CLINT1 | clathrin interactor 1 | -0.0366868 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0366758 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0364922 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0356985 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0352342 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.03469 |
| CD44 | CD44 molecule (Indian blood group) | -0.034679 |
| COL5A1 | collagen, type V, alpha 1 | -0.0341727 |
| PTK2 | protein tyrosine kinase 2 | -0.033892 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0337059 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0328258 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0328086 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0327629 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0326651 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0323825 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0323443 |
| VCL | vinculin | -0.0323223 |
| ANLN | anillin, actin binding protein | -0.0322074 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0321881 |
| HLA-B | major histocompatibility complex, class I, B | -0.0320732 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0320678 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0316455 |
| FUS | FUS RNA binding protein | -0.0314479 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0311317 |
| CTBP2 | C-terminal binding protein 2 | -0.0306888 |
| USP3 | ubiquitin specific peptidase 3 | -0.0306439 |
| MTDH | metadherin | -0.030347 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.0303303 |
| SCFD2 | sec1 family domain containing 2 | -0.0303052 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0303021 |
| WDR45B | WD repeat domain 45B | -0.0301514 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0301011 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0300768 |
| MAP4 | microtubule-associated protein 4 | -0.0300731 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0299463 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0298621 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0296697 |
| INHBA | inhibin, beta A | -0.0296658 |
| RACK1 | receptor for activated C kinase 1 | -0.0296344 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0296218 |
| FNIP1 | folliculin interacting protein 1 | -0.0294557 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.029417 |
| SEPTIN7 | septin 7 | -0.0293805 |
| GLG1 | golgi glycoprotein 1 | -0.0292726 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0289813 |
| CDK13 | cyclin-dependent kinase 13 | -0.0289283 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0289228 |
