| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.160283 |
| DSCAM | Down syndrome cell adhesion molecule | 0.136006 |
| GOLGA4 | golgin A4 | 0.0778525 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0704927 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0689675 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.064086 |
| EZR | ezrin | 0.0640673 |
| VMP1 | vacuole membrane protein 1 | 0.062751 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0606117 |
| CCNL1 | cyclin L1 | 0.0596768 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0585724 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0585601 |
| ARF4 | ADP-ribosylation factor 4 | 0.0576545 |
| RBM25 | RNA binding motif protein 25 | 0.0568205 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0525315 |
| SETD5 | SET domain containing 5 | 0.0516999 |
| PRRC2C | proline-rich coiled-coil 2C | 0.050784 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0495096 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0493651 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0487761 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0471585 |
| ANKRD12 | ankyrin repeat domain 12 | 0.046843 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.046701 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0460655 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0453729 |
| OGA | O-GlcNAcase | 0.0450945 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0449153 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0443271 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0439188 |
| PTEN | phosphatase and tensin homolog | 0.0434875 |
| YME1L1 | YME1-like 1 ATPase | 0.0430603 |
| FTL | ferritin, light polypeptide | 0.0427062 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0423257 |
| ZNF292 | zinc finger protein 292 | 0.0421005 |
| SON | SON DNA binding protein | 0.0420757 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0417623 |
| MATR3 | matrin 3 | 0.0416029 |
| TMF1 | TATA element modulatory factor 1 | 0.0416025 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0411755 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0408169 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0399739 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0394071 |
| RHOA | ras homolog family member A | 0.0382027 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0380649 |
| TPR | translocated promoter region, nuclear basket protein | 0.0379757 |
| ZNF654 | zinc finger protein 654 | 0.0371493 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0370153 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0369213 |
| TPM4 | tropomyosin 4 | 0.0367187 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0366251 |
| RAB10 | RAB10, member RAS oncogene family | 0.0364564 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0364519 |
| EXOC6B | exocyst complex component 6B | 0.0364301 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0361406 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.036031 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.035957 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0358992 |
| TJP1 | tight junction protein 1 | 0.0354893 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0352982 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0352541 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0352197 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0350774 |
| EREG | epiregulin | 0.0348768 |
| RBM39 | RNA binding motif protein 39 | 0.0348528 |
| TMEM87A | transmembrane protein 87A | 0.0344826 |
| XPO1 | exportin 1 | 0.0342025 |
| PNN | pinin, desmosome associated protein | 0.0338843 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0338753 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0334337 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0332925 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0331097 |
| FNBP4 | formin binding protein 4 | 0.033092 |
| JMJD1C | jumonji domain containing 1C | 0.0327973 |
| AFF4 | AF4/FMR2 family, member 4 | 0.03276 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0325865 |
| RTN4 | reticulon 4 | 0.0325515 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0325036 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0323892 |
| RBM26 | RNA binding motif protein 26 | 0.0321176 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.032068 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0320299 |
| ERBIN | erbb2 interacting protein | 0.0319238 |
| PCDHB16 | protocadherin beta 16 | 0.0318904 |
| PCM1 | pericentriolar material 1 | 0.0317139 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0316583 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0316338 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0316318 |
| YTHDC1 | YTH domain containing 1 | 0.0312402 |
| TENM3 | teneurin transmembrane protein 3 | 0.0311278 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0310377 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0310259 |
| UBAP1 | ubiquitin associated protein 1 | 0.030869 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0304023 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0301472 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0300033 |
| KIF5B | kinesin family member 5B | 0.0298585 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0298401 |
| SETD2 | SET domain containing 2 | 0.0297237 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0292923 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.029155 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.214132 |
| PTMA | prothymosin, alpha | -0.137794 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.134627 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.107921 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0944257 |
| INTS6 | integrator complex subunit 6 | -0.0842752 |
| FAT1 | FAT atypical cadherin 1 | -0.0699195 |
| AHNAK | AHNAK nucleoprotein | -0.0675015 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0616194 |
| SERINC5 | serine incorporator 5 | -0.0577287 |
| CTBP2 | C-terminal binding protein 2 | -0.0575428 |
| WWOX | WW domain containing oxidoreductase | -0.0514697 |
| LRRC23 | leucine rich repeat containing 23 | -0.0446255 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.043112 |
| FHIT | fragile histidine triad | -0.0429167 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0426473 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0398687 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0373138 |
| CADPS | Ca++-dependent secretion activator | -0.0372315 |
| TMSB10 | thymosin beta 10 | -0.0362403 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0350104 |
| ACTG1 | actin gamma 1 | -0.0339316 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0327795 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.031928 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0317174 |
| FOXO3 | forkhead box O3 | -0.0314964 |
| FRMD5 | FERM domain containing 5 | -0.0312966 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0308973 |
| HMGA2 | high mobility group AT-hook 2 | -0.0307529 |
| HELLS | helicase, lymphoid-specific | -0.030682 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0305091 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0302475 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0295413 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0287757 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0287182 |
| GPC5 | glypican 5 | -0.0283276 |
| EGFR | epidermal growth factor receptor | -0.0278153 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0267294 |
| H1-0 | H1.0 linker histone | -0.0266352 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0260671 |
| KLHL29 | kelch-like family member 29 | -0.0255928 |
| EGR1 | early growth response 1 | -0.0254919 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0252314 |
| PKM | pyruvate kinase, muscle | -0.0251367 |
| CCND1 | cyclin D1 | -0.0248403 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.024623 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0243867 |
| ADD1 | adducin 1 (alpha) | -0.0242993 |
| FUS | FUS RNA binding protein | -0.0234396 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0232251 |
| UBC | ubiquitin C | -0.022934 |
| ITGB4 | integrin, beta 4 | -0.0228347 |
| PGK1 | phosphoglycerate kinase 1 | -0.0228022 |
| HOMER1 | homer scaffolding protein 1 | -0.0226735 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0226134 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0222775 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0220995 |
| FNIP1 | folliculin interacting protein 1 | -0.0220101 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0218244 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0216678 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0215611 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0214773 |
| DENND1A | DENN/MADD domain containing 1A | -0.0214505 |
| TMEM123 | transmembrane protein 123 | -0.0214231 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0208686 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0208245 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0206108 |
| SNX14 | sorting nexin 14 | -0.0205329 |
| ARF1 | ADP-ribosylation factor 1 | -0.0205151 |
| ZNF395 | zinc finger protein 395 | -0.0204835 |
| DIAPH2 | diaphanous-related formin 2 | -0.0202905 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0202056 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0199652 |
| LASP1 | LIM and SH3 protein 1 | -0.0199651 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0199438 |
| RCC1 | regulator of chromosome condensation 1 | -0.01989 |
| BAIAP2 | BAI1-associated protein 2 | -0.0198268 |
| PALD1 | phosphatase domain containing, paladin 1 | -0.0196673 |
| HPCAL1 | hippocalcin-like 1 | -0.0193227 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0192742 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0192314 |
| FLNA | filamin A, alpha | -0.0190983 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0187391 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0187153 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0185633 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0185607 |
| SH3BP4 | SH3-domain binding protein 4 | -0.018414 |
| SH3BP2 | SH3-domain binding protein 2 | -0.0182896 |
| ONECUT3 | one cut homeobox 3 | -0.0177213 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0177106 |
| PAQR5 | progestin and adipoQ receptor family member V | -0.0173266 |
| H1-4 | H1.4 linker histone, cluster member | -0.0172997 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0169978 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0168367 |
| TFRC | transferrin receptor | -0.0167136 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0166227 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | -0.0165717 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0165552 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0165343 |
| MYOF | myoferlin | -0.0165141 |
