| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.0247069 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0194301 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.017815 |
| FAM13A | family with sequence similarity 13, member A | 0.0165388 |
| ARRDC3 | arrestin domain containing 3 | 0.016514 |
| NGLY1 | N-glycanase 1 | 0.0137702 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0136624 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0135372 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0112545 |
| GOLGA4 | golgin A4 | 0.0105528 |
| CD109 | CD109 molecule | 0.0100484 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.00958078 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.00929295 |
| TXNIP | thioredoxin interacting protein | 0.00898223 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.00842305 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00840558 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00785263 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00762519 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00730556 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.00720897 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.00698919 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00670084 |
| FOSL2 | FOS-like antigen 2 | 0.0065976 |
| EZR | ezrin | 0.00654968 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.00652564 |
| ZNF160 | zinc finger protein 160 | 0.00650222 |
| CUL4B | cullin 4B | 0.00649081 |
| INSIG2 | insulin induced gene 2 | 0.00620876 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00614374 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.00611148 |
| ARFGEF3 | ARFGEF family member 3 | 0.00609074 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00607491 |
| TMF1 | TATA element modulatory factor 1 | 0.00597666 |
| AMN1 | antagonist of mitotic exit network 1 homolog (S. cerevisiae) | 0.00593855 |
| KYNU | kynureninase | 0.00588247 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.00582588 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.00578715 |
| FOSL1 | FOS-like antigen 1 | 0.00576508 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.00576326 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.00572764 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0056542 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00564889 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00555593 |
| FAM219A | family with sequence similarity 219, member A | 0.00541287 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00538077 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0053517 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.00530256 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00528215 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.00526817 |
| CCDC47 | coiled-coil domain containing 47 | 0.00524226 |
| SERINC1 | serine incorporator 1 | 0.00524054 |
| DEPP1 | DEPP autophagy regulator 1 | 0.00518242 |
| NEK2 | NIMA-related kinase 2 | 0.00514742 |
| TXNRD1 | thioredoxin reductase 1 | 0.00511425 |
| OGA | O-GlcNAcase | 0.00498166 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0049573 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.00489618 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.00486068 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00485988 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00483616 |
| CEP70 | centrosomal protein 70kDa | 0.00481934 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00478438 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.00476272 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.00469421 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00468991 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00467551 |
| SFXN1 | sideroflexin 1 | 0.00463336 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.00462619 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.00461004 |
| RNF220 | ring finger protein 220 | 0.00460375 |
| MKRN1 | makorin ring finger protein 1 | 0.004556 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00454709 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.00452399 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.00449537 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0044484 |
| KIAA1958 | KIAA1958 | 0.0043921 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.00437725 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0043649 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00433966 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0043135 |
| LMNB1 | lamin B1 | 0.00430718 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.00429397 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.00426199 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.00423906 |
| RPS18 | ribosomal protein S18 | 0.00423878 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.00422344 |
| B2M | beta-2-microglobulin | 0.00422317 |
| CASC3 | cancer susceptibility candidate 3 | 0.00421633 |
| TCP1 | t-complex 1 | 0.00421538 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.00419836 |
| CCDC93 | coiled-coil domain containing 93 | 0.00414911 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.00414134 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.00412659 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0041197 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00405887 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.00405645 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00405451 |
| SPAG5 | sperm associated antigen 5 | 0.00401173 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.00396422 |
| CDON | cell adhesion associated, oncogene regulated | 0.00395557 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.285867 |
| FN1 | fibronectin 1 | -0.226947 |
| HMGA2 | high mobility group AT-hook 2 | -0.15517 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.138453 |
| EXT1 | exostosin glycosyltransferase 1 | -0.13485 |
| COL5A1 | collagen, type V, alpha 1 | -0.133457 |
| CDH13 | cadherin 13 | -0.12058 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.118715 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.107738 |
| TMSB10 | thymosin beta 10 | -0.106983 |
| MYO10 | myosin X | -0.106118 |
| IGF2 | insulin-like growth factor 2 | -0.105054 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.104835 |
| CD44 | CD44 molecule (Indian blood group) | -0.104441 |
| ASPH | aspartate beta-hydroxylase | -0.103657 |
| ACTG1 | actin gamma 1 | -0.0971164 |
| NAV1 | neuron navigator 1 | -0.0908903 |
| RAI14 | retinoic acid induced 14 | -0.0898022 |
| AHNAK | AHNAK nucleoprotein | -0.0846306 |
| COL6A3 | collagen, type VI, alpha 3 | -0.080335 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0781368 |
| COL6A1 | collagen, type VI, alpha 1 | -0.073561 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0691397 |
| CLMP | CXADR-like membrane protein | -0.0671831 |
| DST | dystonin | -0.0643378 |
| GLIS3 | GLIS family zinc finger 3 | -0.0636551 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0635532 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.063187 |
| VCL | vinculin | -0.0603195 |
| ANXA2 | annexin A2 | -0.0599204 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0571976 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0514331 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0512848 |
| PGK1 | phosphoglycerate kinase 1 | -0.0505763 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.050525 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0491184 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0486352 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0484391 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0483996 |
| CCND1 | cyclin D1 | -0.0483982 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0469344 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0460074 |
| ANKRD11 | ankyrin repeat domain 11 | -0.045881 |
| LAMB3 | laminin, beta 3 | -0.0447862 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0444303 |
| PTK2 | protein tyrosine kinase 2 | -0.0440947 |
| PTMA | prothymosin, alpha | -0.0434624 |
| STC1 | stanniocalcin 1 | -0.0430812 |
| TENM2 | teneurin transmembrane protein 2 | -0.0429178 |
| RRBP1 | ribosome binding protein 1 | -0.0427675 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0412133 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0406663 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0406211 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0404166 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0402024 |
| DIAPH2 | diaphanous-related formin 2 | -0.0401945 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0401571 |
| TUBB6 | tubulin, beta 6 class V | -0.0398419 |
| ENO1 | enolase 1, (alpha) | -0.0394788 |
| PRKCA | protein kinase C, alpha | -0.0392855 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0388097 |
| COL1A1 | collagen, type I, alpha 1 | -0.0384806 |
| MAP1B | microtubule-associated protein 1B | -0.0379026 |
| FRMD4A | FERM domain containing 4A | -0.0378589 |
| INHBA | inhibin, beta A | -0.0377799 |
| EGR1 | early growth response 1 | -0.0375442 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.037262 |
| PRSS23 | protease, serine, 23 | -0.0371157 |
| CUX1 | cut-like homeobox 1 | -0.0359839 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0359747 |
| EGFR | epidermal growth factor receptor | -0.0355742 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0351349 |
| FMN1 | formin 1 | -0.034761 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0344168 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0343928 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0341048 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0338948 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0338802 |
| CLIC4 | chloride intracellular channel 4 | -0.0328012 |
| MAP4 | microtubule-associated protein 4 | -0.032695 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0321395 |
| TPM4 | tropomyosin 4 | -0.0319053 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0312795 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0310076 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0305617 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0300151 |
| CALU | calumenin | -0.0299752 |
| KIAA1549L | KIAA1549-like | -0.0297894 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0297712 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0295527 |
| S100A10 | S100 calcium binding protein A10 | -0.0294781 |
| RAD51B | RAD51 paralog B | -0.029182 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0290968 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.029083 |
| FBXO11 | F-box protein 11 | -0.0288485 |
| CDCP1 | CUB domain containing protein 1 | -0.0287675 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0287004 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0286907 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0281201 |
| NF1 | neurofibromin 1 | -0.0280228 |
