| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0880295 |
| KRT20 | keratin 20, type I | 0.0829289 |
| KRT18 | keratin 18, type I | 0.0799698 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0767285 |
| KRT8 | keratin 8, type II | 0.0722693 |
| B2M | beta-2-microglobulin | 0.0643313 |
| JUN | jun proto-oncogene | 0.0609093 |
| LDHA | lactate dehydrogenase A | 0.0573473 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.057012 |
| VEGFA | vascular endothelial growth factor A | 0.0567712 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0541271 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0503075 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0475527 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0474627 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0473879 |
| TMSB10 | thymosin beta 10 | 0.0462825 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0442379 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0422522 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0408217 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0375492 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0354115 |
| RNF213 | ring finger protein 213 | 0.0344529 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0338241 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0323261 |
| RPL23 | ribosomal protein L23 | 0.0320727 |
| PGK1 | phosphoglycerate kinase 1 | 0.0319825 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0317031 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0315952 |
| ENO1 | enolase 1, (alpha) | 0.0311737 |
| DIAPH2 | diaphanous-related formin 2 | 0.031106 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0309974 |
| AHNAK | AHNAK nucleoprotein | 0.0285152 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0281882 |
| FRY | furry homolog (Drosophila) | 0.02807 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0280267 |
| TMSB4X | thymosin beta 4, X-linked | 0.0264591 |
| POF1B | premature ovarian failure, 1B | 0.0256622 |
| KRT19 | keratin 19, type I | 0.0256005 |
| FTL | ferritin, light polypeptide | 0.0253583 |
| TRIB1 | tribbles pseudokinase 1 | 0.0253093 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0248017 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0245699 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0242505 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.0235038 |
| ANXA2 | annexin A2 | 0.0235002 |
| MUC13 | mucin 13, cell surface associated | 0.023374 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0233179 |
| SDC4 | syndecan 4 | 0.0228418 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0226769 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0226692 |
| FOXP1 | forkhead box P1 | 0.0226545 |
| RPL13A | ribosomal protein L13a | 0.0224434 |
| EPS8L1 | EPS8-like 1 | 0.0223799 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0222375 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0218661 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0217116 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0215456 |
| KLF10 | Kruppel-like factor 10 | 0.0213805 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0212748 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0212339 |
| TNS3 | tensin 3 | 0.0211733 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0211062 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0210797 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0209305 |
| CLDN4 | claudin 4 | 0.0208733 |
| RPS3 | ribosomal protein S3 | 0.020842 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.020543 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0205098 |
| HMGA2 | high mobility group AT-hook 2 | 0.0204909 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0204902 |
| CA12 | carbonic anhydrase XII | 0.0201838 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.0201608 |
| RDH13 | retinol dehydrogenase 13 (all-trans/9-cis) | 0.0200362 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0200027 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.0198248 |
| CBX3 | chromobox homolog 3 | 0.0195835 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0193639 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0192502 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.0191235 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0191053 |
| MCL1 | myeloid cell leukemia 1 | 0.0190912 |
| FN1 | fibronectin 1 | 0.019022 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0188271 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.0188172 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa | 0.0187629 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0186909 |
| GSN | gelsolin | 0.0184008 |
| VIM | vimentin | 0.0183346 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0183146 |
| ASPH | aspartate beta-hydroxylase | 0.0182487 |
| TPI1 | triosephosphate isomerase 1 | 0.0180319 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0178934 |
| LAMB3 | laminin, beta 3 | 0.0178393 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0178265 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.0178101 |
| PYGB | phosphorylase, glycogen; brain | 0.0176563 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0176293 |
| EGR1 | early growth response 1 | 0.0176039 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0168633 |
| MYO18A | myosin XVIIIA | 0.0168486 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.122607 |
| EXT1 | exostosin glycosyltransferase 1 | -0.118464 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.110427 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0986821 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0889307 |
| RPS6 | ribosomal protein S6 | -0.0832368 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0822833 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.08187 |
| JMJD1C | jumonji domain containing 1C | -0.0816858 |
| RPS2 | ribosomal protein S2 | -0.0781783 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0755967 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0750554 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.070557 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0693506 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0686643 |
| SBF2 | SET binding factor 2 | -0.0660969 |
| GOLGA4 | golgin A4 | -0.0649961 |
| PDZD8 | PDZ domain containing 8 | -0.0619618 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0616832 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.061472 |
| RBM39 | RNA binding motif protein 39 | -0.0609901 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0600545 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0557813 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0552687 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0533934 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0523127 |
| COG5 | component of oligomeric golgi complex 5 | -0.0521154 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0506226 |
| CLTC | clathrin, heavy chain (Hc) | -0.0495299 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0483658 |
| HM13 | histocompatibility (minor) 13 | -0.0479564 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.047788 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0477408 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0475132 |
| TJP1 | tight junction protein 1 | -0.0466522 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0464866 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0464691 |
| PHF20L1 | PHD finger protein 20-like 1 | -0.0462096 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0460432 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0455511 |
| NDRG1 | N-myc downstream regulated 1 | -0.044646 |
| FAM135A | family with sequence similarity 135, member A | -0.043956 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0438005 |
| RPL21 | ribosomal protein L21 | -0.0432969 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0430996 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0422537 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0421709 |
| NF1 | neurofibromin 1 | -0.0421478 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0420406 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0418946 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0417398 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0416922 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0413799 |
| WWC1 | WW and C2 domain containing 1 | -0.0413099 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0405599 |
| PTK2 | protein tyrosine kinase 2 | -0.0402633 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0401133 |
| BCL2L1 | BCL2-like 1 | -0.0398821 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0398352 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0393654 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0392678 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0392307 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0391496 |
| ZNF207 | zinc finger protein 207 | -0.0390177 |
| FOXO1 | forkhead box O1 | -0.0390051 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0389944 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0382816 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0374338 |
| IPO7 | importin 7 | -0.0373863 |
| EXPH5 | exophilin 5 | -0.0373068 |
| TES | testin LIM domain protein | -0.0370971 |
| SUCO | SUN domain containing ossification factor | -0.0370817 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0369398 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0367117 |
| ADNP | activity-dependent neuroprotector homeobox | -0.036171 |
| RTN3 | reticulon 3 | -0.0361293 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0360823 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0359214 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0357639 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0356064 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0354799 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0353504 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | -0.0350383 |
| FAM91A1 | family with sequence similarity 91, member A1 | -0.0348675 |
| SLMAP | sarcolemma associated protein | -0.0348179 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0346688 |
| USP34 | ubiquitin specific peptidase 34 | -0.0346143 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0344783 |
| SMAD3 | SMAD family member 3 | -0.0344415 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0344137 |
| EHF | ets homologous factor | -0.0343125 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0341054 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0337625 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0337133 |
| CD2AP | CD2-associated protein | -0.0334471 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0333709 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0333508 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0332766 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0332305 |
| PSPC1 | paraspeckle component 1 | -0.0330425 |
