| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.256822 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.161559 |
| FN1 | fibronectin 1 | 0.128022 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0802866 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0790972 |
| CD44 | CD44 molecule (Indian blood group) | 0.0772888 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0680583 |
| COL5A1 | collagen, type V, alpha 1 | 0.0661088 |
| ASPH | aspartate beta-hydroxylase | 0.0616271 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0582212 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0547116 |
| ERBIN | erbb2 interacting protein | 0.053921 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0532546 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0481121 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0473122 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0447772 |
| ZNF432 | zinc finger protein 432 | 0.0436779 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0431705 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0426707 |
| MSN | moesin | 0.0416656 |
| DST | dystonin | 0.0404722 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.040137 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0397793 |
| FLNB | filamin B, beta | 0.0392441 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0385301 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0381957 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0381425 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.036247 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0361837 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.035861 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0347727 |
| INTS6 | integrator complex subunit 6 | 0.0345405 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.034137 |
| MCL1 | myeloid cell leukemia 1 | 0.0340104 |
| VEGFA | vascular endothelial growth factor A | 0.0334957 |
| OSMR | oncostatin M receptor | 0.0331655 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0330579 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0327684 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0327457 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0325735 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0322742 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0317756 |
| PODXL | podocalyxin-like | 0.0311058 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0308942 |
| ENO1 | enolase 1, (alpha) | 0.0307157 |
| POTEF | POTE ankyrin domain family, member F | 0.0297867 |
| ATXN1 | ataxin 1 | 0.0295682 |
| RAI14 | retinoic acid induced 14 | 0.0292557 |
| SMYD3 | SET and MYND domain containing 3 | 0.0290665 |
| FOXP1 | forkhead box P1 | 0.0288797 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0285851 |
| VMP1 | vacuole membrane protein 1 | 0.0283892 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0278724 |
| ZNF841 | zinc finger protein 841 | 0.0278565 |
| GLIS3 | GLIS family zinc finger 3 | 0.0277598 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0276492 |
| VCL | vinculin | 0.0274851 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0268104 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0265927 |
| RAD51B | RAD51 paralog B | 0.0263471 |
| PTK2 | protein tyrosine kinase 2 | 0.026327 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0258234 |
| NAV1 | neuron navigator 1 | 0.0256916 |
| KLF12 | Kruppel-like factor 12 | 0.0255582 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0253941 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0247864 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0241118 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0239984 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0238664 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0236942 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0236005 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0232552 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0232121 |
| TENM3 | teneurin transmembrane protein 3 | 0.0230689 |
| LOX | lysyl oxidase | 0.0223623 |
| FAM120A | family with sequence similarity 120A | 0.0220394 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0220011 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0218501 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0212898 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0212116 |
| SETX | senataxin | 0.0211919 |
| VEGFC | vascular endothelial growth factor C | 0.0211412 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0208449 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0208431 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0205425 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0204769 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0203713 |
| TPM3 | tropomyosin 3 | 0.0202637 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0202414 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0201544 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0201443 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0201272 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0200923 |
| SEPTIN9 | septin 9 | 0.0199979 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.019922 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0197809 |
| DIAPH2 | diaphanous-related formin 2 | 0.0196719 |
| LOXL2 | lysyl oxidase-like 2 | 0.0196536 |
| ACTN1 | actinin, alpha 1 | 0.0193912 |
| EGFR | epidermal growth factor receptor | 0.0193683 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.244575 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16096 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.140412 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.100041 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0961474 |
| DEK | DEK proto-oncogene | -0.0726217 |
| PTMA | prothymosin, alpha | -0.0677106 |
| HLA-B | major histocompatibility complex, class I, B | -0.0653543 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0620779 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0494596 |
| RPS6 | ribosomal protein S6 | -0.0477626 |
| HMGB1 | high mobility group box 1 | -0.0465148 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0453977 |
| GOLGA4 | golgin A4 | -0.0445204 |
| ATP13A3 | ATPase type 13A3 | -0.0397661 |
| ADM | adrenomedullin | -0.0395559 |
| RPL35A | ribosomal protein L35a | -0.0393856 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0393063 |
| RLF | rearranged L-myc fusion | -0.0385272 |
| RBM39 | RNA binding motif protein 39 | -0.0383744 |
| RPS8 | ribosomal protein S8 | -0.0381359 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0375196 |
| NOP58 | NOP58 ribonucleoprotein | -0.0372791 |
| RPL12 | ribosomal protein L12 | -0.0371777 |
| TPD52 | tumor protein D52 | -0.036798 |
| USP3 | ubiquitin specific peptidase 3 | -0.0355125 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0354129 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0352784 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0340038 |
| SPAG9 | sperm associated antigen 9 | -0.0339387 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0336438 |
| TMSB10 | thymosin beta 10 | -0.0331465 |
| JUN | jun proto-oncogene | -0.0330354 |
| ZNF292 | zinc finger protein 292 | -0.0329231 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0320087 |
| S100A10 | S100 calcium binding protein A10 | -0.031958 |
| GNAS | GNAS complex locus | -0.0318625 |
| RPLP2 | ribosomal protein, large, P2 | -0.0315925 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0315345 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0309948 |
| TUBB | tubulin, beta class I | -0.0306298 |
| YBX1 | Y box binding protein 1 | -0.0303734 |
| HMGB2 | high mobility group box 2 | -0.0303611 |
| NUP58 | nucleoporin 58 | -0.0300599 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0300071 |
| RPL11 | ribosomal protein L11 | -0.0296919 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0294717 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0294391 |
| CALR | calreticulin | -0.0291345 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0291138 |
| ANXA1 | annexin A1 | -0.0287225 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0280976 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0279311 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0275026 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0274954 |
| TKT | transketolase | -0.0273191 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0272221 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0269336 |
| WTAP | Wilms tumor 1 associated protein | -0.0269175 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0264457 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0260291 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0256501 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0255626 |
| RPL26 | ribosomal protein L26 | -0.025367 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0253245 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.024854 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.024497 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0242444 |
| SEPTIN7 | septin 7 | -0.0241903 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0240482 |
| RPL35 | ribosomal protein L35 | -0.0240389 |
| QKI | QKI, KH domain containing, RNA binding | -0.0240048 |
| SQSTM1 | sequestosome 1 | -0.0238933 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0238887 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0238399 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0237397 |
| ACTG1 | actin gamma 1 | -0.0236572 |
| PLIN2 | perilipin 2 | -0.0235742 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.023365 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0231076 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0230265 |
| MLF1 | myeloid leukemia factor 1 | -0.0229996 |
| RPLP1 | ribosomal protein, large, P1 | -0.0228956 |
| MATR3 | matrin 3 | -0.0228608 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0228476 |
| RPL19 | ribosomal protein L19 | -0.0228268 |
| KRT18 | keratin 18, type I | -0.0226966 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0225536 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0222303 |
| TFG | TRK-fused gene | -0.0222108 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0219559 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0218664 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0218279 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.021727 |
| RPL5 | ribosomal protein L5 | -0.0216482 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0216299 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0215307 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0214407 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.021423 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0213125 |
