| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.023769 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0199942 |
| FRMD6 | FERM domain containing 6 | 0.0172387 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0169253 |
| KYNU | kynureninase | 0.0167589 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0164124 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0163479 |
| BRD2 | bromodomain containing 2 | 0.0162238 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.01599 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0158779 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0139617 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0133169 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0128548 |
| SMAD3 | SMAD family member 3 | 0.0120776 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0116698 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0114991 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0113766 |
| NEK7 | NIMA-related kinase 7 | 0.0108283 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0105402 |
| CUL3 | cullin 3 | 0.00997096 |
| GSK3B | glycogen synthase kinase 3 beta | 0.00980484 |
| YTHDC1 | YTH domain containing 1 | 0.00939266 |
| SKIL | SKI-like proto-oncogene | 0.00939071 |
| COL12A1 | collagen, type XII, alpha 1 | 0.00935975 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.00923646 |
| ETNK1 | ethanolamine kinase 1 | 0.00905176 |
| ITGAV | integrin, alpha V | 0.0089749 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.00880302 |
| MEMO1 | mediator of cell motility 1 | 0.00874376 |
| CDK19 | cyclin-dependent kinase 19 | 0.00866402 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00866052 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 0.00857098 |
| ATP13A3 | ATPase type 13A3 | 0.00848684 |
| INTS6 | integrator complex subunit 6 | 0.00845318 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | 0.00830337 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00828838 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.00826699 |
| TJP1 | tight junction protein 1 | 0.00826106 |
| ALPK2 | alpha-kinase 2 | 0.00819787 |
| NPC1 | Niemann-Pick disease, type C1 | 0.00819154 |
| OSMR | oncostatin M receptor | 0.00817937 |
| CD163L1 | CD163 molecule-like 1 | 0.00796619 |
| WDR26 | WD repeat domain 26 | 0.00795618 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.00791356 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00786588 |
| WDR43 | WD repeat domain 43 | 0.0077439 |
| CCNL1 | cyclin L1 | 0.00768111 |
| ERBIN | erbb2 interacting protein | 0.00765256 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.00763554 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.00760239 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00752502 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.00748566 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00738748 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.00731018 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | 0.00724017 |
| PANK3 | pantothenate kinase 3 | 0.00713455 |
| RNF10 | ring finger protein 10 | 0.00706418 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.00695928 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00694811 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00694236 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.00691699 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.00689572 |
| VCL | vinculin | 0.00683039 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.00681303 |
| CPNE1 | copine I | 0.0067077 |
| SPIDR | scaffolding protein involved in DNA repair | 0.00662223 |
| SESN1 | sestrin 1 | 0.00659548 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.00658828 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.00656734 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.00653546 |
| EXOC6B | exocyst complex component 6B | 0.00651274 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.00649737 |
| YME1L1 | YME1-like 1 ATPase | 0.00635045 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.00631833 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.00631159 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.00617862 |
| FBXO38 | F-box protein 38 | 0.00616607 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 | 0.00616257 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.00614957 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.00613819 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.00609836 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | 0.00609047 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.00604702 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00603523 |
| RTN4 | reticulon 4 | 0.00595905 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.00594681 |
| GLCCI1 | glucocorticoid induced 1 | 0.00593579 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.00588603 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0057817 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) | 0.00577586 |
| UBAP2 | ubiquitin associated protein 2 | 0.00577462 |
| KIF3A | kinesin family member 3A | 0.00577086 |
| HEATR5B | HEAT repeat containing 5B | 0.00575926 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.00575429 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.00573881 |
| RAB22A | RAB22A, member RAS oncogene family | 0.00572778 |
| GPATCH2 | G patch domain containing 2 | 0.005727 |
| CREB1 | cAMP responsive element binding protein 1 | 0.00569745 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.00569549 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00569497 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.314893 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.200794 |
| TMSB10 | thymosin beta 10 | -0.132142 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.10711 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.10385 |
| DTNA | dystrobrevin, alpha | -0.103306 |
| EFNA5 | ephrin-A5 | -0.101867 |
| RPS6 | ribosomal protein S6 | -0.100548 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0971573 |
| LSAMP | limbic system-associated membrane protein | -0.0955677 |
| PTMA | prothymosin, alpha | -0.0946858 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0932787 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0919207 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0888989 |
| GPC6 | glypican 6 | -0.0843614 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0842578 |
| MMP12 | matrix metallopeptidase 12 | -0.0803817 |
| CDH13 | cadherin 13 | -0.0801391 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0800073 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0785452 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.076128 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.072656 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.068059 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0671814 |
| KIAA1549L | KIAA1549-like | -0.0624961 |
| ANXA2 | annexin A2 | -0.0618002 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0569682 |
| ASPH | aspartate beta-hydroxylase | -0.0568815 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0560418 |
| PGK1 | phosphoglycerate kinase 1 | -0.0556136 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0555587 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0529265 |
| KIAA1217 | KIAA1217 | -0.0516864 |
| TPM4 | tropomyosin 4 | -0.0515555 |
| LDHA | lactate dehydrogenase A | -0.0498617 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0497175 |
| ACTG1 | actin gamma 1 | -0.0488908 |
| MYO10 | myosin X | -0.0484217 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0482102 |
| AHNAK | AHNAK nucleoprotein | -0.0480053 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0477187 |
| MT2A | metallothionein 2A | -0.047674 |
| PTK2 | protein tyrosine kinase 2 | -0.0469211 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0467043 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0466802 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0447396 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0446122 |
| RUNX1 | runt-related transcription factor 1 | -0.0445805 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0444076 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0443285 |
| RPS8 | ribosomal protein S8 | -0.0441164 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0440694 |
| NAV1 | neuron navigator 1 | -0.04392 |
| NTM | neurotrimin | -0.043234 |
| RPS3 | ribosomal protein S3 | -0.0430937 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0427258 |
| RPL37A | ribosomal protein L37a | -0.0419885 |
| CDK6 | cyclin-dependent kinase 6 | -0.0416094 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0410229 |
| DST | dystonin | -0.0409361 |
| RPL35A | ribosomal protein L35a | -0.0408486 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.040818 |
| RPLP1 | ribosomal protein, large, P1 | -0.0403833 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0395878 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0384541 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0383927 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0382347 |
| NDRG1 | N-myc downstream regulated 1 | -0.0382099 |
| PKM | pyruvate kinase, muscle | -0.0381096 |
| RPS27A | ribosomal protein S27a | -0.0370299 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0368817 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0363308 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0351267 |
| RPL12 | ribosomal protein L12 | -0.0348453 |
| CAVIN1 | caveolae associated protein 1 | -0.0346818 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0337395 |
| PARD3 | par-3 family cell polarity regulator | -0.0336134 |
| GNAS | GNAS complex locus | -0.0336024 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0335811 |
| ENO1 | enolase 1, (alpha) | -0.0325833 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0325544 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0324706 |
| SBF2 | SET binding factor 2 | -0.0320788 |
| EGR1 | early growth response 1 | -0.0320674 |
| RPL23 | ribosomal protein L23 | -0.03141 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0313659 |
| FN1 | fibronectin 1 | -0.0308533 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0307392 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0305343 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0296675 |
| RPLP0 | ribosomal protein, large, P0 | -0.029614 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0294492 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0293729 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0292717 |
| RPS19 | ribosomal protein S19 | -0.0292387 |
| RPS12 | ribosomal protein S12 | -0.0292013 |
| ITGA6 | integrin, alpha 6 | -0.0288036 |
| RPS25 | ribosomal protein S25 | -0.0286449 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0284621 |
| RPL31 | ribosomal protein L31 | -0.0284046 |
