| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.103786 |
| CALB1 | calbindin 1, 28kDa | 0.0893136 |
| LMO7 | LIM domain 7 | 0.0836108 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.073697 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0587611 |
| EZR | ezrin | 0.0536291 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0506155 |
| DSPP | dentin sialophosphoprotein | 0.0497323 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0491618 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0476337 |
| CCNL1 | cyclin L1 | 0.0450727 |
| FLNB | filamin B, beta | 0.0448288 |
| RBM25 | RNA binding motif protein 25 | 0.0439438 |
| MSI2 | musashi RNA-binding protein 2 | 0.0438977 |
| MYOF | myoferlin | 0.0415591 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0413552 |
| OXSR1 | oxidative stress responsive 1 | 0.0412053 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0397939 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0396391 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0391884 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0390995 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0389105 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0380344 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0378141 |
| FAT1 | FAT atypical cadherin 1 | 0.0377714 |
| POTEF | POTE ankyrin domain family, member F | 0.0352532 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0343483 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.03419 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.033816 |
| PCBP2 | poly(rC) binding protein 2 | 0.0337824 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0310885 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.031015 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.030424 |
| LAMA4 | laminin, alpha 4 | 0.0293666 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0288395 |
| NRDC | nardilysin convertase | 0.0284883 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0276063 |
| TMF1 | TATA element modulatory factor 1 | 0.0271574 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0269978 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0266035 |
| ARF4 | ADP-ribosylation factor 4 | 0.0264857 |
| CLDN4 | claudin 4 | 0.0260945 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.0260726 |
| SH3D19 | SH3 domain containing 19 | 0.0260321 |
| BRD2 | bromodomain containing 2 | 0.025199 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0249843 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0248727 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0248462 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0247515 |
| RPL21 | ribosomal protein L21 | 0.0247081 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0244469 |
| PLAC8 | placenta-specific 8 | 0.0241632 |
| VEGFA | vascular endothelial growth factor A | 0.023857 |
| SETD5 | SET domain containing 5 | 0.0234738 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0231898 |
| PTK2 | protein tyrosine kinase 2 | 0.0231703 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0231257 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0229374 |
| BPTF | bromodomain PHD finger transcription factor | 0.0228428 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0227951 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0222062 |
| AOPEP | aminopeptidase O (putative) | 0.0221795 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0219084 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.02163 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0215575 |
| SLTM | SAFB-like, transcription modulator | 0.0212911 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0212702 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0210471 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0210247 |
| ANXA11 | annexin A11 | 0.020843 |
| EPHA2 | EPH receptor A2 | 0.0208417 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0208159 |
| SLK | STE20-like kinase | 0.020511 |
| CAV2 | caveolin 2 | 0.0203945 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0203408 |
| TJP1 | tight junction protein 1 | 0.0203345 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0200346 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0199742 |
| SULF2 | sulfatase 2 | 0.0198336 |
| GOLGA4 | golgin A4 | 0.0198287 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0197531 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.019613 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0195529 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0189906 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.018856 |
| MLEC | malectin | 0.0188014 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0187249 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.01861 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0184417 |
| RIN2 | Ras and Rab interactor 2 | 0.0183018 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.018282 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0181201 |
| FNBP4 | formin binding protein 4 | 0.018077 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0180742 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0179996 |
| NPSR1 | neuropeptide S receptor 1 | 0.01794 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0178575 |
| CD9 | CD9 molecule | 0.0178082 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0177205 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0175306 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.176782 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.142779 |
| RPLP1 | ribosomal protein, large, P1 | -0.139963 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111602 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0901731 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0683874 |
| PRELID2 | PRELI domain containing 2 | -0.0660476 |
| RPLP0 | ribosomal protein, large, P0 | -0.0649127 |
| RPS8 | ribosomal protein S8 | -0.0565033 |
| RPS24 | ribosomal protein S24 | -0.0544733 |
| PRSS3 | protease, serine, 3 | -0.0523023 |
| RPL34 | ribosomal protein L34 | -0.0515314 |
| RPL26 | ribosomal protein L26 | -0.0506559 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0492637 |
| RPL35A | ribosomal protein L35a | -0.0470697 |
| CANX | calnexin | -0.0435366 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0431379 |
| RPL11 | ribosomal protein L11 | -0.0428664 |
| RPL23 | ribosomal protein L23 | -0.0421055 |
| RPL13A | ribosomal protein L13a | -0.0406061 |
| RPS27A | ribosomal protein S27a | -0.0405431 |
| RPS21 | ribosomal protein S21 | -0.0405016 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0403699 |
| SERINC5 | serine incorporator 5 | -0.0398327 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0389261 |
| ABHD17C | abhydrolase domain containing 17C | -0.0372353 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0364348 |
| RPL12 | ribosomal protein L12 | -0.0362289 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0359962 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0354133 |
| ATXN1 | ataxin 1 | -0.0350435 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0349834 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0339874 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.033646 |
| NDRG1 | N-myc downstream regulated 1 | -0.0333992 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0331461 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0331353 |
| TMSB10 | thymosin beta 10 | -0.0330869 |
| RRBP1 | ribosome binding protein 1 | -0.0327597 |
| SMYD3 | SET and MYND domain containing 3 | -0.03189 |
| MUC13 | mucin 13, cell surface associated | -0.0304644 |
| RPS23 | ribosomal protein S23 | -0.0302438 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0300044 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0291248 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0289106 |
| RPL9 | ribosomal protein L9 | -0.0283014 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0279309 |
| RPL28 | ribosomal protein L28 | -0.0279155 |
| RPS6 | ribosomal protein S6 | -0.0279066 |
| RPL37A | ribosomal protein L37a | -0.0278199 |
| FHIT | fragile histidine triad | -0.0272396 |
| SHROOM3 | shroom family member 3 | -0.0272282 |
| CXADR | coxsackie virus and adenovirus receptor | -0.026956 |
| ENO1 | enolase 1, (alpha) | -0.0267648 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0266628 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0262983 |
| KLF6 | Kruppel-like factor 6 | -0.0262362 |
| FUS | FUS RNA binding protein | -0.0261578 |
| FRMD5 | FERM domain containing 5 | -0.0257558 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0256668 |
| RPS2 | ribosomal protein S2 | -0.0255989 |
| RPS20 | ribosomal protein S20 | -0.0255688 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0255648 |
| RPS15 | ribosomal protein S15 | -0.0255436 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0250969 |
| RAD51B | RAD51 paralog B | -0.0250949 |
| FOXO1 | forkhead box O1 | -0.0249555 |
| EREG | epiregulin | -0.0249542 |
| RPS16 | ribosomal protein S16 | -0.024931 |
| RPS19 | ribosomal protein S19 | -0.0248118 |
| RPLP2 | ribosomal protein, large, P2 | -0.0247745 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0247269 |
| RPS4X | ribosomal protein S4, X-linked | -0.0243854 |
| TMEM45B | transmembrane protein 45B | -0.0243741 |
| RPL32 | ribosomal protein L32 | -0.0242839 |
| RPS25 | ribosomal protein S25 | -0.0242575 |
| RPL38 | ribosomal protein L38 | -0.0242204 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0242087 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0239504 |
| OGA | O-GlcNAcase | -0.0236489 |
| HSPA8 | heat shock 70kDa protein 8 | -0.023627 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0235618 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0230551 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0228194 |
| ASPH | aspartate beta-hydroxylase | -0.0226029 |
| HMGB2 | high mobility group box 2 | -0.0224957 |
| PTMA | prothymosin, alpha | -0.0222632 |
| RNF145 | ring finger protein 145 | -0.0220746 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.021519 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0213824 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0212679 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0211984 |
| RPL14 | ribosomal protein L14 | -0.0210658 |
| RPL6 | ribosomal protein L6 | -0.0209807 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0208161 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0203077 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0202246 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0202093 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0201809 |
| NCOA7 | nuclear receptor coactivator 7 | -0.020041 |
