| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0268716 |
| DST | dystonin | 0.0261412 |
| TXNRD1 | thioredoxin reductase 1 | 0.0252468 |
| AHNAK | AHNAK nucleoprotein | 0.0241836 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0213983 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0209268 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0179663 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0151441 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0142787 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0141236 |
| RUNX1 | runt-related transcription factor 1 | 0.0136632 |
| JUN | jun proto-oncogene | 0.0126119 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.012307 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0123052 |
| HOMER1 | homer scaffolding protein 1 | 0.0116819 |
| HDAC9 | histone deacetylase 9 | 0.0114307 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0110181 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0108533 |
| CAPRIN2 | caprin family member 2 | 0.0108106 |
| EMP1 | epithelial membrane protein 1 | 0.0108071 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0106694 |
| ANGPTL4 | angiopoietin-like 4 | 0.0106266 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0105562 |
| INTS6 | integrator complex subunit 6 | 0.0104938 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0101124 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0101014 |
| RAI1 | retinoic acid induced 1 | 0.010054 |
| RPL4 | ribosomal protein L4 | 0.00989641 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.00930776 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0092519 |
| MYOF | myoferlin | 0.0090249 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.00899691 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0086073 |
| CMIP | c-Maf inducing protein | 0.00838675 |
| GOLGB1 | golgin B1 | 0.00829015 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.00820864 |
| CANX | calnexin | 0.00817734 |
| PRELID2 | PRELI domain containing 2 | 0.00817412 |
| EGFR | epidermal growth factor receptor | 0.0077647 |
| CFAP299 | cilia and flagella associated protein 299 | 0.00774294 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00770621 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00770595 |
| UPP1 | uridine phosphorylase 1 | 0.00766778 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.00765949 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.00760458 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.00758394 |
| NEK10 | NIMA-related kinase 10 | 0.00758127 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.00758075 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.00755605 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.00745234 |
| GOLGA3 | golgin A3 | 0.00741818 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.00730803 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.00723126 |
| HDLBP | high density lipoprotein binding protein | 0.00709994 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00708931 |
| ERCC1 | excision repair cross-complementation group 1 | 0.00707247 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.00700187 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0069847 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00693258 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.00675677 |
| APP | amyloid beta (A4) precursor protein | 0.00669821 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0066896 |
| LYST | lysosomal trafficking regulator | 0.00667867 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00666659 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00666084 |
| NAV2 | neuron navigator 2 | 0.00658025 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.00657188 |
| DOCK11 | dedicator of cytokinesis 11 | 0.00645937 |
| CACNG8 | calcium channel, voltage-dependent, gamma subunit 8 | 0.00644746 |
| LOXL2 | lysyl oxidase-like 2 | 0.00638353 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 | 0.00629825 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.00628794 |
| PHF21A | PHD finger protein 21A | 0.00618686 |
| WDR27 | WD repeat domain 27 | 0.00612275 |
| DOCK1 | dedicator of cytokinesis 1 | 0.00601524 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00600074 |
| ZNF146 | zinc finger protein 146 | 0.00598119 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.00596397 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.00591283 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.00588381 |
| RGS4 | regulator of G-protein signaling 4 | 0.00582541 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00582025 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.00581186 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00566305 |
| AFF3 | AF4/FMR2 family, member 3 | 0.00564282 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00563146 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.00559643 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.00559309 |
| MLPH | melanophilin | 0.00558503 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.00555132 |
| CEP250 | centrosomal protein 250kDa | 0.00554876 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.00551651 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.00540315 |
| PATJ | PATJ crumbs cell polarity complex component | 0.00538781 |
| EHBP1 | EH domain binding protein 1 | 0.0053405 |
| FER | fer (fps/fes related) tyrosine kinase | 0.00527627 |
| GOLGA1 | golgin A1 | 0.00527091 |
| DSPP | dentin sialophosphoprotein | 0.00521985 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.00521908 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.00519494 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205915 |
| VIM | vimentin | -0.0924612 |
| TMSB10 | thymosin beta 10 | -0.0743428 |
| PTMA | prothymosin, alpha | -0.0733434 |
| POTEF | POTE ankyrin domain family, member F | -0.0663594 |
| MT2A | metallothionein 2A | -0.0648938 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0590321 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0426964 |
| HMGA1 | high mobility group AT-hook 1 | -0.038815 |
| HLA-B | major histocompatibility complex, class I, B | -0.0374953 |
| RPL35A | ribosomal protein L35a | -0.0369269 |
| FTL | ferritin, light polypeptide | -0.0323384 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0316408 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0315498 |
| RPS6 | ribosomal protein S6 | -0.0308001 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0305582 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0304375 |
| ACTG1 | actin gamma 1 | -0.0288578 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0288226 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0283827 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0239882 |
| RPS19 | ribosomal protein S19 | -0.0239026 |
| ENO1 | enolase 1, (alpha) | -0.0236277 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.023467 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0232688 |
| LOC112694756 | uncharaterized LOC112694756 | -0.023013 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0227885 |
| PKM | pyruvate kinase, muscle | -0.0219273 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0206447 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0206102 |
| TPI1 | triosephosphate isomerase 1 | -0.0203941 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0203295 |
| RPS8 | ribosomal protein S8 | -0.0202192 |
| RBM25 | RNA binding motif protein 25 | -0.0200202 |
| RPL12 | ribosomal protein L12 | -0.0197469 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0196311 |
| RPS23 | ribosomal protein S23 | -0.0196204 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0195894 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0193329 |
| RPLP2 | ribosomal protein, large, P2 | -0.0192554 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0192142 |
| RPL36 | ribosomal protein L36 | -0.0191158 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0189749 |
| RPL31 | ribosomal protein L31 | -0.0188634 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0188081 |
| RPL23 | ribosomal protein L23 | -0.0187186 |
| PFN1 | profilin 1 | -0.0184829 |
| CD44 | CD44 molecule (Indian blood group) | -0.0184375 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0183658 |
| SRGN | serglycin | -0.0181956 |
| RPS24 | ribosomal protein S24 | -0.0181562 |
| PGK1 | phosphoglycerate kinase 1 | -0.0179987 |
| RPL37A | ribosomal protein L37a | -0.0178158 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0175897 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0171448 |
| RPL28 | ribosomal protein L28 | -0.0168667 |
| RAB7A | RAB7A, member RAS oncogene family | -0.016781 |
| TAPBP | TAP binding protein (tapasin) | -0.0166367 |
| HLA-A | major histocompatibility complex, class I, A | -0.016613 |
| RPL11 | ribosomal protein L11 | -0.0165575 |
| PCBP2 | poly(rC) binding protein 2 | -0.016455 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0163173 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0162733 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0161539 |
| RPS12 | ribosomal protein S12 | -0.0158948 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0156618 |
| S100A9 | S100 calcium binding protein A9 | -0.0156526 |
| EGR1 | early growth response 1 | -0.0155253 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0154025 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0153974 |
| RPLP1 | ribosomal protein, large, P1 | -0.0153266 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0152062 |
| RPL26 | ribosomal protein L26 | -0.0152028 |
| TOP1 | topoisomerase (DNA) I | -0.0151897 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | -0.0151851 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0150508 |
| GNAS | GNAS complex locus | -0.0149442 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.014928 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0148928 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0147889 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0147358 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.014735 |
| RPL35 | ribosomal protein L35 | -0.0147187 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.014668 |
| OLA1 | Obg-like ATPase 1 | -0.0146541 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0145343 |
| FOSL1 | FOS-like antigen 1 | -0.0145311 |
| ZNF207 | zinc finger protein 207 | -0.0144704 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0144657 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.01446 |
| XPO1 | exportin 1 | -0.0144074 |
| B2M | beta-2-microglobulin | -0.0143381 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.014275 |
| MATR3 | matrin 3 | -0.0142512 |
| ZNF292 | zinc finger protein 292 | -0.0142407 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0141092 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0139827 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0139822 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0139655 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0138318 |
