| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.139892 |
| ASPH | aspartate beta-hydroxylase | 0.139517 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.115892 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.110404 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0887274 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0851394 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0753037 |
| EFNA5 | ephrin-A5 | 0.0688472 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0627168 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0605809 |
| MCL1 | myeloid cell leukemia 1 | 0.0598261 |
| INTS6 | integrator complex subunit 6 | 0.0596081 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0555406 |
| SLTM | SAFB-like, transcription modulator | 0.0528248 |
| LMO7 | LIM domain 7 | 0.0496876 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0494832 |
| RNF213 | ring finger protein 213 | 0.04813 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0476356 |
| SCEL | sciellin | 0.045891 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0450697 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0441371 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0426485 |
| FOXP1 | forkhead box P1 | 0.0425707 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0417753 |
| VCL | vinculin | 0.0415395 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0414251 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0396675 |
| TXNRD1 | thioredoxin reductase 1 | 0.038833 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0381651 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0373746 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0367825 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0358192 |
| GRAMD1B | GRAM domain containing 1B | 0.035781 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0354616 |
| AREG | amphiregulin | 0.0351289 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0343607 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0341992 |
| LAMC2 | laminin, gamma 2 | 0.033934 |
| NTN4 | netrin 4 | 0.0320961 |
| DSPP | dentin sialophosphoprotein | 0.0313703 |
| MYO1E | myosin IE | 0.0306422 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0306393 |
| CAV2 | caveolin 2 | 0.0296604 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0294442 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0294258 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0292991 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0291857 |
| PRKCA | protein kinase C, alpha | 0.0291233 |
| CUX1 | cut-like homeobox 1 | 0.028802 |
| HOMER1 | homer scaffolding protein 1 | 0.0285723 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0280954 |
| SMYD3 | SET and MYND domain containing 3 | 0.0277401 |
| TNS3 | tensin 3 | 0.0275935 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0273959 |
| CPE | carboxypeptidase E | 0.0273907 |
| CMIP | c-Maf inducing protein | 0.0273465 |
| VMP1 | vacuole membrane protein 1 | 0.0270835 |
| MYO1D | myosin ID | 0.0269725 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0267002 |
| MYOF | myoferlin | 0.0259346 |
| PKM | pyruvate kinase, muscle | 0.0258549 |
| CCND1 | cyclin D1 | 0.0257891 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0256948 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0255487 |
| POTEF | POTE ankyrin domain family, member F | 0.0250854 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0249695 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0245915 |
| RAD51B | RAD51 paralog B | 0.0244497 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0243179 |
| MSN | moesin | 0.0242902 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0242086 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0240483 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.023874 |
| EHBP1 | EH domain binding protein 1 | 0.0238249 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0238117 |
| TPM4 | tropomyosin 4 | 0.0235794 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0234734 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0234497 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0232389 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0232147 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0231431 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0229661 |
| KRT7 | keratin 7, type II | 0.0228555 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0227062 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0226937 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0226867 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0225362 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.022259 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0222212 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0220137 |
| KRT8 | keratin 8, type II | 0.0220026 |
| SP100 | SP100 nuclear antigen | 0.0219058 |
| PLS3 | plastin 3 | 0.0218326 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0218116 |
| LAMA4 | laminin, alpha 4 | 0.0217515 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0216752 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.021667 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0216218 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0213672 |
| KYNU | kynureninase | 0.0212568 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.216235 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.153839 |
| NDRG1 | N-myc downstream regulated 1 | -0.110972 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.108989 |
| H1-0 | H1.0 linker histone | -0.0757472 |
| FAM13A | family with sequence similarity 13, member A | -0.0733127 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0691827 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0659056 |
| TMEM165 | transmembrane protein 165 | -0.0653551 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0634638 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0587288 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0571181 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0546557 |
| NGLY1 | N-glycanase 1 | -0.0513738 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0460539 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0459703 |
| PTMA | prothymosin, alpha | -0.04354 |
| PGK1 | phosphoglycerate kinase 1 | -0.0427455 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0427216 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0416248 |
| WDR45B | WD repeat domain 45B | -0.0411085 |
| MT2A | metallothionein 2A | -0.0388597 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.038807 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0387508 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0386042 |
| MORF4L2 | mortality factor 4 like 2 | -0.0381217 |
| HELZ | helicase with zinc finger | -0.0380738 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0376976 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0374962 |
| UVRAG | UV radiation resistance associated | -0.0362389 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0359555 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0358931 |
| OGA | O-GlcNAcase | -0.0349038 |
| RUNX1 | runt-related transcription factor 1 | -0.0348068 |
| SEPTIN2 | septin 2 | -0.0347428 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0345675 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0337598 |
| HBP1 | HMG-box transcription factor 1 | -0.0337142 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0335842 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0334919 |
| RBM39 | RNA binding motif protein 39 | -0.0334853 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0334126 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0333832 |
| SEC61G | Sec61 gamma subunit | -0.0333393 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0331692 |
| RPS24 | ribosomal protein S24 | -0.0330286 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0329861 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0321822 |
| RPLP1 | ribosomal protein, large, P1 | -0.0317779 |
| HDLBP | high density lipoprotein binding protein | -0.0315378 |
| SPAG9 | sperm associated antigen 9 | -0.0314099 |
| ZNF292 | zinc finger protein 292 | -0.0311833 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0304371 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0302893 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0301198 |
| TOP1 | topoisomerase (DNA) I | -0.0299919 |
| RNF145 | ring finger protein 145 | -0.0299023 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0293812 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0291843 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0283417 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0282592 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0281596 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0280852 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0280772 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0275973 |
| ARRDC3 | arrestin domain containing 3 | -0.0275775 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0270612 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0266588 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0264171 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0263178 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0262359 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0260843 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0260631 |
| DTNA | dystrobrevin, alpha | -0.0257543 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0257019 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0256527 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0255125 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0252337 |
| RPL34 | ribosomal protein L34 | -0.0251963 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0251604 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0251367 |
| FTL | ferritin, light polypeptide | -0.0248441 |
| WASF2 | WAS protein family, member 2 | -0.0248264 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0242915 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0242563 |
| TPD52 | tumor protein D52 | -0.0240713 |
| PDE8A | phosphodiesterase 8A | -0.023913 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0238801 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0237991 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0237669 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0237393 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0235257 |
| IER3 | immediate early response 3 | -0.0233504 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0233325 |
| SQSTM1 | sequestosome 1 | -0.0232912 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0229279 |
| FNIP1 | folliculin interacting protein 1 | -0.0227695 |
| LAMB3 | laminin, beta 3 | -0.0227123 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0226808 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0224798 |
