| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLGA4 | golgin A4 | 0.0588412 |
| DSCAM | Down syndrome cell adhesion molecule | 0.044714 |
| RBM39 | RNA binding motif protein 39 | 0.0444671 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0370937 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0290101 |
| OGA | O-GlcNAcase | 0.0280507 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0251562 |
| VMP1 | vacuole membrane protein 1 | 0.024626 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0245497 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0235039 |
| SCFD1 | sec1 family domain containing 1 | 0.0234537 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0233906 |
| COG5 | component of oligomeric golgi complex 5 | 0.023284 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0230578 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0228493 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0224041 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0222503 |
| RUNX2 | runt-related transcription factor 2 | 0.0205738 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0204175 |
| SRP54 | signal recognition particle 54kDa | 0.0202548 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0199536 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0197587 |
| ARF4 | ADP-ribosylation factor 4 | 0.019669 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.019191 |
| CCNL1 | cyclin L1 | 0.0190524 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.018858 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0187155 |
| FAM3C | family with sequence similarity 3, member C | 0.0182503 |
| VEGFA | vascular endothelial growth factor A | 0.0181865 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0181368 |
| YME1L1 | YME1-like 1 ATPase | 0.0179125 |
| EXOC6B | exocyst complex component 6B | 0.0178738 |
| RPL4 | ribosomal protein L4 | 0.0177366 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0176525 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.01744 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0170153 |
| RBM25 | RNA binding motif protein 25 | 0.0169888 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0169234 |
| AHR | aryl hydrocarbon receptor | 0.0163138 |
| DOCK5 | dedicator of cytokinesis 5 | 0.016114 |
| PRELID2 | PRELI domain containing 2 | 0.0160285 |
| CD109 | CD109 molecule | 0.0160092 |
| CAB39 | calcium binding protein 39 | 0.015853 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0158192 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | 0.0156096 |
| USP34 | ubiquitin specific peptidase 34 | 0.0154113 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0153779 |
| FNBP4 | formin binding protein 4 | 0.0153317 |
| ATP13A3 | ATPase type 13A3 | 0.0151688 |
| COPA | coatomer protein complex, subunit alpha | 0.0151251 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0148424 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0148004 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0146822 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0146614 |
| SMAD3 | SMAD family member 3 | 0.0145813 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0145647 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0144978 |
| TTLL10 | tubulin tyrosine ligase-like family member 10 | 0.0142938 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0141689 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0140741 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0140398 |
| ATXN10 | ataxin 10 | 0.0140394 |
| NBAS | neuroblastoma amplified sequence | 0.0138054 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0136663 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0136359 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0135166 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0134029 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0133568 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0133328 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.013132 |
| VWDE | von Willebrand factor D and EGF domains | 0.0130177 |
| GOLGA3 | golgin A3 | 0.0129913 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0128714 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0128119 |
| SUCO | SUN domain containing ossification factor | 0.0127655 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0127596 |
| PNN | pinin, desmosome associated protein | 0.0125411 |
| BLTP3B | bridge-like lipid transfer protein family member 3B | 0.012423 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | 0.0123883 |
| SMC5 | structural maintenance of chromosomes 5 | 0.012371 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0123615 |
| METTL15 | methyltransferase like 15 | 0.0123566 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0123403 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0123126 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0123072 |
| USP47 | ubiquitin specific peptidase 47 | 0.0122846 |
| MTREX | Mtr4 exosome RNA helicase | 0.012256 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0121825 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0121578 |
| MORF4L2 | mortality factor 4 like 2 | 0.0121073 |
| IL1R1 | interleukin 1 receptor, type I | 0.0119533 |
| KIAA1328 | KIAA1328 | 0.0119423 |
| RBM33 | RNA binding motif protein 33 | 0.0118327 |
| PGM3 | phosphoglucomutase 3 | 0.0118268 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0117828 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0117061 |
| YTHDC1 | YTH domain containing 1 | 0.011699 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0115789 |
| GPHN | gephyrin | 0.0115455 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.011467 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.237445 |
| VIM | vimentin | -0.187011 |
| TMSB10 | thymosin beta 10 | -0.159509 |
| FN1 | fibronectin 1 | -0.14289 |
| LOX | lysyl oxidase | -0.0936584 |
| FTL | ferritin, light polypeptide | -0.0908101 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0781657 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0776273 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0769427 |
| STC1 | stanniocalcin 1 | -0.0759263 |
| PTMA | prothymosin, alpha | -0.0754639 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0752653 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.071891 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0688902 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0688733 |
| HMGA2 | high mobility group AT-hook 2 | -0.0682917 |
| CDH13 | cadherin 13 | -0.0673657 |
| NDRG1 | N-myc downstream regulated 1 | -0.0672777 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0624631 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0621235 |
| ENO1 | enolase 1, (alpha) | -0.0592423 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0568747 |
| S100A6 | S100 calcium binding protein A6 | -0.0556589 |
| B2M | beta-2-microglobulin | -0.0548265 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0532357 |
| RPLP1 | ribosomal protein, large, P1 | -0.0524138 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0521416 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0507043 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0499119 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0485789 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.048426 |
| MTSS1 | metastasis suppressor 1 | -0.0471168 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0467329 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0439426 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0438725 |
| NRG1 | neuregulin 1 | -0.0432194 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0431318 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0429772 |
| IER3 | immediate early response 3 | -0.0423428 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0420665 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0409415 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0396727 |
| CD44 | CD44 molecule (Indian blood group) | -0.0387041 |
| RPS19 | ribosomal protein S19 | -0.038607 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0384682 |
| PKM | pyruvate kinase, muscle | -0.0382427 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0381808 |
| S100A10 | S100 calcium binding protein A10 | -0.0380948 |
| CA12 | carbonic anhydrase XII | -0.0377876 |
| MT2A | metallothionein 2A | -0.0371562 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.036549 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0361665 |
| ASPH | aspartate beta-hydroxylase | -0.0356439 |
| PGK1 | phosphoglycerate kinase 1 | -0.0347169 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0346034 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0344719 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0341392 |
| GPC6 | glypican 6 | -0.0332108 |
| FAM20C | family with sequence similarity 20, member C | -0.0328726 |
| RPL35A | ribosomal protein L35a | -0.0325784 |
| TMSB4X | thymosin beta 4, X-linked | -0.0315665 |
| RPS6 | ribosomal protein S6 | -0.0314995 |
| RPS8 | ribosomal protein S8 | -0.0313671 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0312357 |
| CLMP | CXADR-like membrane protein | -0.031224 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0312148 |
| RPL31 | ribosomal protein L31 | -0.0311188 |
| RPL34 | ribosomal protein L34 | -0.0307039 |
| LDHA | lactate dehydrogenase A | -0.0303622 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0303289 |
| RPS21 | ribosomal protein S21 | -0.0302226 |
| PRSS23 | protease, serine, 23 | -0.0300944 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0300583 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0300248 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0299754 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0298696 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.029551 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0292119 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0286543 |
| RPL32 | ribosomal protein L32 | -0.0283318 |
| NUMB | numb homolog (Drosophila) | -0.0281524 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0281475 |
| DIAPH2 | diaphanous-related formin 2 | -0.0281442 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0280725 |
| RPS24 | ribosomal protein S24 | -0.0279355 |
| FBN1 | fibrillin 1 | -0.0273366 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.027308 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0271452 |
| RIOK3 | RIO kinase 3 | -0.0271205 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0270665 |
| UBC | ubiquitin C | -0.0267432 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0264587 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0263867 |
| GNAS | GNAS complex locus | -0.026341 |
| RPLP2 | ribosomal protein, large, P2 | -0.0262026 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0259863 |
| SFTPA2 | surfactant protein A2 | -0.0258316 |
| RPL11 | ribosomal protein L11 | -0.0258022 |
| ANGPTL4 | angiopoietin-like 4 | -0.0257693 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0256936 |
