| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.118233 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0695924 |
| TXNRD1 | thioredoxin reductase 1 | 0.0629378 |
| CCNL1 | cyclin L1 | 0.0601233 |
| WDR43 | WD repeat domain 43 | 0.056307 |
| NRG1 | neuregulin 1 | 0.0531006 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0447971 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0445154 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0438319 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0430346 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0429357 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0421695 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0323483 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0322996 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0321633 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0314537 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0304928 |
| FGB | fibrinogen beta chain | 0.0298719 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0298144 |
| PFDN2 | prefoldin subunit 2 | 0.0290066 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0285632 |
| CPNE8 | copine VIII | 0.028288 |
| USP3 | ubiquitin specific peptidase 3 | 0.0279948 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0279528 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0268809 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0268163 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0261353 |
| RTN4 | reticulon 4 | 0.0258883 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0254256 |
| TPM3 | tropomyosin 3 | 0.0249285 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0245851 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0245041 |
| SP3 | Sp3 transcription factor | 0.0233252 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.022877 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0225135 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.022484 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.02242 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0223058 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.02222 |
| SERINC1 | serine incorporator 1 | 0.0220564 |
| WWOX | WW domain containing oxidoreductase | 0.0217878 |
| PNN | pinin, desmosome associated protein | 0.0214664 |
| APP | amyloid beta (A4) precursor protein | 0.0213565 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0212527 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.020994 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0209768 |
| PHF3 | PHD finger protein 3 | 0.0208464 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0205734 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0204122 |
| ZNF292 | zinc finger protein 292 | 0.0200617 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0199096 |
| CD109 | CD109 molecule | 0.0198985 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0196245 |
| MATR3 | matrin 3 | 0.0196006 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0195773 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0193761 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0193187 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0190741 |
| SSH1 | slingshot protein phosphatase 1 | 0.0190365 |
| SMAD3 | SMAD family member 3 | 0.018896 |
| RUNX1 | runt-related transcription factor 1 | 0.0186567 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0185173 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0184865 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.0183364 |
| YY1AP1 | YY1 associated protein 1 | 0.0181905 |
| SIN3A | SIN3 transcription regulator family member A | 0.0179988 |
| XPO1 | exportin 1 | 0.0178613 |
| CCNY | cyclin Y | 0.0173593 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0173461 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0171833 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.016994 |
| KLC1 | kinesin light chain 1 | 0.0169511 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.0168776 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0168652 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0168295 |
| NUP58 | nucleoporin 58 | 0.016773 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.016734 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0166774 |
| ITSN2 | intersectin 2 | 0.0166165 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0161508 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0161484 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0161184 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | 0.0160793 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.01582 |
| ATXN1 | ataxin 1 | 0.0157683 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0157585 |
| RBM25 | RNA binding motif protein 25 | 0.0156629 |
| USP22 | ubiquitin specific peptidase 22 | 0.0155608 |
| SUMO1 | small ubiquitin-like modifier 1 | 0.0154746 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0154384 |
| CDC42SE2 | CDC42 small effector 2 | 0.0154073 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0153968 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0153761 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.015289 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0152391 |
| GOLM2 | golgi membrane protein 2 | 0.0152261 |
| UCK2 | uridine-cytidine kinase 2 | 0.0152249 |
| LYPLA1 | lysophospholipase I | 0.0151869 |
| NEK7 | NIMA-related kinase 7 | 0.0150897 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0150771 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.253194 |
| TMSB10 | thymosin beta 10 | -0.18107 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.174479 |
| MT2A | metallothionein 2A | -0.150695 |
| FTL | ferritin, light polypeptide | -0.132097 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.110838 |
| IGF2 | insulin-like growth factor 2 | -0.101157 |
| VIM | vimentin | -0.0976416 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0837026 |
| ACTG1 | actin gamma 1 | -0.0786331 |
| EGR1 | early growth response 1 | -0.0784615 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0687956 |
| POTEF | POTE ankyrin domain family, member F | -0.0673249 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0636822 |
| PM20D1 | peptidase M20 domain containing 1 | -0.063183 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0619006 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0615956 |
| CMIP | c-Maf inducing protein | -0.0603011 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0596184 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0574969 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0563354 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0536312 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0534676 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0533676 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0526023 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0518321 |
| KYNU | kynureninase | -0.0517645 |
| PKM | pyruvate kinase, muscle | -0.0517542 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0511361 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.044628 |
| PDLIM5 | PDZ and LIM domain 5 | -0.043653 |
| PFN1 | profilin 1 | -0.0431911 |
| CFDP1 | craniofacial development protein 1 | -0.0418186 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.040315 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.040159 |
| ANXA1 | annexin A1 | -0.0400086 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0383446 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0376003 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0373457 |
| PDE10A | phosphodiesterase 10A | -0.0369275 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0360858 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0353688 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0351107 |
| RPL19 | ribosomal protein L19 | -0.0349849 |
| PLS3 | plastin 3 | -0.0347356 |
| CUX1 | cut-like homeobox 1 | -0.0340837 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0339784 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0334367 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0334318 |
| S100A10 | S100 calcium binding protein A10 | -0.033395 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0331141 |
| FMNL2 | formin-like 2 | -0.0326587 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.032561 |
| COPA | coatomer protein complex, subunit alpha | -0.0325368 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.032278 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0314748 |
| FLNB | filamin B, beta | -0.0314426 |
| INO80 | INO80 complex subunit | -0.0313389 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0312804 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0312021 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0307331 |
| ERBIN | erbb2 interacting protein | -0.0304553 |
| RHOA | ras homolog family member A | -0.0303838 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0302198 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0301887 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0299914 |
| BRD2 | bromodomain containing 2 | -0.0298638 |
| RPL28 | ribosomal protein L28 | -0.0295806 |
| HDLBP | high density lipoprotein binding protein | -0.0292454 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0292271 |
| HLA-A | major histocompatibility complex, class I, A | -0.028601 |
| FUS | FUS RNA binding protein | -0.0285873 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0283676 |
| NEGR1 | neuronal growth regulator 1 | -0.0282336 |
| S100A6 | S100 calcium binding protein A6 | -0.0277858 |
| CALR | calreticulin | -0.0276456 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.027582 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0275351 |
| IL6 | interleukin 6 | -0.0274552 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0274522 |
| TPI1 | triosephosphate isomerase 1 | -0.0269341 |
| LMNA | lamin A/C | -0.0265902 |
| RAD51B | RAD51 paralog B | -0.0259971 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0256974 |
| S100A11 | S100 calcium binding protein A11 | -0.0256401 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | -0.0252488 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0248311 |
| RPS27A | ribosomal protein S27a | -0.0247108 |
| BMPR1B | bone morphogenetic protein receptor, type IB | -0.0246431 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0245608 |
| JMJD1C | jumonji domain containing 1C | -0.0243739 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0243606 |
| RPS6 | ribosomal protein S6 | -0.0240623 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0239462 |
| MLF1 | myeloid leukemia factor 1 | -0.0237119 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0236913 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0235396 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -0.0235254 |
| IER3 | immediate early response 3 | -0.0234893 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0234408 |
