| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYOF | myoferlin | 0.116195 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0932036 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0927196 |
| VIM | vimentin | 0.0823222 |
| FAM13A | family with sequence similarity 13, member A | 0.0738936 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0734798 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0715532 |
| PDE10A | phosphodiesterase 10A | 0.0709238 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0700039 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0665291 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0650008 |
| GPC6 | glypican 6 | 0.0639296 |
| B2M | beta-2-microglobulin | 0.063861 |
| RLF | rearranged L-myc fusion | 0.0633146 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0615986 |
| ZNF292 | zinc finger protein 292 | 0.0614248 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0610294 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0590008 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0584248 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0562592 |
| MEF2A | myocyte enhancer factor 2A | 0.0541045 |
| DST | dystonin | 0.0540292 |
| HELZ | helicase with zinc finger | 0.0535791 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0532481 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0518189 |
| CCNL1 | cyclin L1 | 0.0506477 |
| PGK1 | phosphoglycerate kinase 1 | 0.0493592 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0489428 |
| MORF4L2 | mortality factor 4 like 2 | 0.0487681 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0484571 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0476315 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.046862 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0464307 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0461513 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0458785 |
| CD44 | CD44 molecule (Indian blood group) | 0.0440573 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0425829 |
| RPL35A | ribosomal protein L35a | 0.0421674 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0418895 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0417805 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0413495 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0407686 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0407259 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0406662 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0394844 |
| ENO1 | enolase 1, (alpha) | 0.0393476 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0391014 |
| SEPTIN9 | septin 9 | 0.0390786 |
| RBM26 | RNA binding motif protein 26 | 0.0381128 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0377711 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0375402 |
| VEGFA | vascular endothelial growth factor A | 0.0372231 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0372 |
| JMJD1C | jumonji domain containing 1C | 0.0369498 |
| SEPTIN7 | septin 7 | 0.0369439 |
| NAV1 | neuron navigator 1 | 0.0368258 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0367884 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0367866 |
| PCBP3 | poly(rC) binding protein 3 | 0.0367575 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0367121 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0365984 |
| CD109 | CD109 molecule | 0.0365916 |
| RBM8A | RNA binding motif protein 8A | 0.0364113 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0360344 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0359849 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0359465 |
| FMNL2 | formin-like 2 | 0.035867 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0357375 |
| USP3 | ubiquitin specific peptidase 3 | 0.0356055 |
| COL5A2 | collagen, type V, alpha 2 | 0.0355205 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0354402 |
| SNX1 | sorting nexin 1 | 0.0353798 |
| RIOK3 | RIO kinase 3 | 0.0353453 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0352979 |
| CCNY | cyclin Y | 0.0352552 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0350811 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.034852 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0348357 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0347219 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0346656 |
| CDK19 | cyclin-dependent kinase 19 | 0.0344342 |
| RBM39 | RNA binding motif protein 39 | 0.0344302 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0341527 |
| SETD5 | SET domain containing 5 | 0.0340985 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0340496 |
| PTMA | prothymosin, alpha | 0.0340075 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0336435 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0333462 |
| APP | amyloid beta (A4) precursor protein | 0.0332054 |
| GOLGA4 | golgin A4 | 0.0329337 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0329022 |
| TXNRD1 | thioredoxin reductase 1 | 0.0328535 |
| RBM25 | RNA binding motif protein 25 | 0.0328423 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0326831 |
| CENPF | centromere protein F, 350/400kDa | 0.0324266 |
| RPL37A | ribosomal protein L37a | 0.031958 |
| OGA | O-GlcNAcase | 0.0316023 |
| RPL8 | ribosomal protein L8 | 0.0315693 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0314874 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0314543 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.186125 |
| LMO7 | LIM domain 7 | -0.15253 |
| KRT17 | keratin 17, type I | -0.134585 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128739 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.103726 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.101365 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.100371 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0968905 |
| MUC16 | mucin 16, cell surface associated | -0.0925626 |
| IGF2 | insulin-like growth factor 2 | -0.0785281 |
| ATOSA | atos homolog A | -0.0757287 |
| MYO1E | myosin IE | -0.0741931 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0738683 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0724979 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0693514 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0677264 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0670419 |
| TJP1 | tight junction protein 1 | -0.0669877 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0668956 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0632547 |
| SLMAP | sarcolemma associated protein | -0.0628558 |
| TMEM165 | transmembrane protein 165 | -0.0621348 |
| SPAG9 | sperm associated antigen 9 | -0.0609623 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0608376 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0604667 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0600419 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0595976 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0587792 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.057547 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0572117 |
| S100A9 | S100 calcium binding protein A9 | -0.055629 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0535752 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0521903 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0520821 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0520291 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0489665 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0482617 |
| ACTG1 | actin gamma 1 | -0.045443 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0451507 |
| MORC3 | MORC family CW-type zinc finger 3 | -0.0449181 |
| CMIP | c-Maf inducing protein | -0.0443097 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0442812 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0442649 |
| EGFR | epidermal growth factor receptor | -0.0439075 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0438741 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0436771 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0433081 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0430787 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0420901 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0416875 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0416039 |
| CA12 | carbonic anhydrase XII | -0.0415715 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0411949 |
| DENND2C | DENN/MADD domain containing 2C | -0.0411671 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.0410949 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.040171 |
| ANXA2 | annexin A2 | -0.0401401 |
| KYNU | kynureninase | -0.0401119 |
| LAMC2 | laminin, gamma 2 | -0.0399294 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0398369 |
| ANXA3 | annexin A3 | -0.0396454 |
| JUP | junction plakoglobin | -0.0391756 |
| STC1 | stanniocalcin 1 | -0.0388571 |
| FLNB | filamin B, beta | -0.0387347 |
| MYO9A | myosin IXA | -0.0387249 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0383085 |
| CDK13 | cyclin-dependent kinase 13 | -0.0380082 |
| S100A11 | S100 calcium binding protein A11 | -0.0376519 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0373383 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.03724 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.037206 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0371536 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0371082 |
| USP53 | ubiquitin specific peptidase 53 | -0.0370414 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.036424 |
| CDYL | chromodomain protein, Y-like | -0.0363029 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | -0.0362873 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0362225 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0361807 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0360081 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0359556 |
| PRDM1 | PR domain containing 1, with ZNF domain | -0.0352585 |
| MYO6 | myosin VI | -0.0350713 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0349703 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0349271 |
| KRT19 | keratin 19, type I | -0.034537 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0341056 |
| NDRG1 | N-myc downstream regulated 1 | -0.0340374 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0339761 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0335197 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0335014 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0332406 |
| CNKSR3 | CNKSR family member 3 | -0.0331633 |
| RND3 | Rho family GTPase 3 | -0.0329719 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0324277 |
| DENND4A | DENN/MADD domain containing 4A | -0.032085 |
| DSG2 | desmoglein 2 | -0.0320758 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0315412 |
| STK17A | serine/threonine kinase 17a | -0.0315174 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0315173 |
