| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.365205 |
| GRAMD1B | GRAM domain containing 1B | 0.151155 |
| MCL1 | myeloid cell leukemia 1 | 0.113522 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0928753 |
| YBX3 | Y box binding protein 3 | 0.0880134 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.084483 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0831206 |
| TXNRD1 | thioredoxin reductase 1 | 0.0787285 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0773788 |
| RAD51B | RAD51 paralog B | 0.0756008 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0710902 |
| SMAD3 | SMAD family member 3 | 0.0651817 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0643042 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0639264 |
| VIM | vimentin | 0.0623691 |
| TPM3 | tropomyosin 3 | 0.0559956 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0548206 |
| MT2A | metallothionein 2A | 0.0528184 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0524658 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0515629 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0513185 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0505394 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0495595 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0491952 |
| CCNL1 | cyclin L1 | 0.0488937 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.047166 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0463766 |
| OSMR | oncostatin M receptor | 0.0458379 |
| HMGA2 | high mobility group AT-hook 2 | 0.0455736 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0454637 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0453915 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0441118 |
| PDE10A | phosphodiesterase 10A | 0.0430677 |
| TPM4 | tropomyosin 4 | 0.0423026 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.042086 |
| FMNL2 | formin-like 2 | 0.0411418 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0408245 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0405799 |
| ENO1 | enolase 1, (alpha) | 0.0396897 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.039685 |
| LDHA | lactate dehydrogenase A | 0.0396427 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0387544 |
| WWOX | WW domain containing oxidoreductase | 0.0385931 |
| DENND5B | DENN/MADD domain containing 5B | 0.0385171 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.037483 |
| DSPP | dentin sialophosphoprotein | 0.0368352 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0363139 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0361967 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0359227 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0342163 |
| PHF21A | PHD finger protein 21A | 0.0340614 |
| KRT18 | keratin 18, type I | 0.0337569 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0337194 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0329701 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0320537 |
| DIAPH2 | diaphanous-related formin 2 | 0.0319532 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0317332 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0316186 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0315841 |
| PLEC | plectin | 0.0315441 |
| RNF213 | ring finger protein 213 | 0.031315 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0311383 |
| AHNAK | AHNAK nucleoprotein | 0.0310586 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0308312 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0308207 |
| BMERB1 | bMERB domain containing 1 | 0.0306126 |
| VCL | vinculin | 0.0305842 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0304848 |
| B2M | beta-2-microglobulin | 0.0299337 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.029914 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0295109 |
| SVIL | supervillin | 0.0293928 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0289503 |
| ERBIN | erbb2 interacting protein | 0.0288873 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0288072 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0287021 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0286869 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0286031 |
| VMP1 | vacuole membrane protein 1 | 0.0284657 |
| DST | dystonin | 0.0284346 |
| KRT8 | keratin 8, type II | 0.0282163 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0280328 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0280224 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0279417 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0279243 |
| CDCP1 | CUB domain containing protein 1 | 0.0278981 |
| STC1 | stanniocalcin 1 | 0.0278679 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0277934 |
| UBTF | upstream binding transcription factor, RNA polymerase I | 0.0276865 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0275604 |
| TMSB10 | thymosin beta 10 | 0.0273156 |
| TCIM | transcriptional and immune response regulator | 0.0270722 |
| PRKCE | protein kinase C, epsilon | 0.0268365 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0267727 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.026661 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0266539 |
| CLDN1 | claudin 1 | 0.026623 |
| RLIM | ring finger protein, LIM domain interacting | 0.0263232 |
| ANO6 | anoctamin 6 | 0.0263121 |
| RIGI | RNA sensor RIG-I | 0.0262797 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.206302 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.1119 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0579614 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0561787 |
| RPS2 | ribosomal protein S2 | -0.0539136 |
| SEPTIN7 | septin 7 | -0.0537794 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.052466 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0505859 |
| PTMA | prothymosin, alpha | -0.0504308 |
| RTN4 | reticulon 4 | -0.049881 |
| CLTC | clathrin, heavy chain (Hc) | -0.0491063 |
| PHIP | pleckstrin homology domain interacting protein | -0.0469267 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0452244 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0437825 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.042157 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0419572 |
| RBM39 | RNA binding motif protein 39 | -0.0408326 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0407037 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0398849 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0395784 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0380409 |
| TFG | TRK-fused gene | -0.0370978 |
| RPS15 | ribosomal protein S15 | -0.0367718 |
| GOLGA4 | golgin A4 | -0.0367113 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0366301 |
| MORF4L2 | mortality factor 4 like 2 | -0.0363676 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0363498 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0358842 |
| NOP58 | NOP58 ribonucleoprotein | -0.0351886 |
| GOLT1B | golgi transport 1B | -0.0351245 |
| CCND2 | cyclin D2 | -0.033582 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0335138 |
| WDR45B | WD repeat domain 45B | -0.0327511 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0327227 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0323896 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0320118 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0318543 |
| SETD5 | SET domain containing 5 | -0.0316326 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0311681 |
| NUP153 | nucleoporin 153kDa | -0.031116 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.031111 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0309873 |
| RPL9 | ribosomal protein L9 | -0.0308164 |
| IGF2 | insulin-like growth factor 2 | -0.0307876 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0306773 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0300057 |
| PCBP2 | poly(rC) binding protein 2 | -0.0297923 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0297208 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0296942 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0296374 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0296333 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.029598 |
| CEP192 | centrosomal protein 192kDa | -0.0289907 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0286538 |
| ACTG1 | actin gamma 1 | -0.0283644 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0281795 |
| RLF | rearranged L-myc fusion | -0.0280233 |
| RPL5 | ribosomal protein L5 | -0.0274778 |
| SMC4 | structural maintenance of chromosomes 4 | -0.027397 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0263879 |
| PRPF4B | pre-mRNA processing factor 4B | -0.0263553 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0262143 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0256262 |
| H1-0 | H1.0 linker histone | -0.025468 |
| RPL37A | ribosomal protein L37a | -0.0253729 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0253602 |
| SRP72 | signal recognition particle 72kDa | -0.025315 |
| RBM33 | RNA binding motif protein 33 | -0.0252974 |
| HELZ | helicase with zinc finger | -0.0250724 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -0.0250302 |
| MKI67 | marker of proliferation Ki-67 | -0.0247509 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0247198 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0241295 |
| RPL38 | ribosomal protein L38 | -0.0235999 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0235962 |
| RPL12 | ribosomal protein L12 | -0.0235824 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0235643 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0235612 |
| RECQL | RecQ helicase-like | -0.0235604 |
| NBAS | neuroblastoma amplified sequence | -0.0233629 |
| RPL26 | ribosomal protein L26 | -0.0233339 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0232365 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0231408 |
| SPAG9 | sperm associated antigen 9 | -0.0228946 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | -0.0228652 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0227981 |
| TMEM263 | transmembrane protein 263 | -0.0226673 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0225193 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.022448 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0222411 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0220198 |
| THOC1 | THO complex 1 | -0.0219075 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0218969 |
| COPA | coatomer protein complex, subunit alpha | -0.0217718 |
| RPS12 | ribosomal protein S12 | -0.021691 |
| OLA1 | Obg-like ATPase 1 | -0.0216876 |
| RASA2 | RAS p21 protein activator 2 | -0.0215894 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0215267 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0214015 |
| QKI | QKI, KH domain containing, RNA binding | -0.0214008 |
