| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GDA | guanine deaminase | 0.12637 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0926839 |
| TXNRD1 | thioredoxin reductase 1 | 0.0878016 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0835692 |
| GRAMD1B | GRAM domain containing 1B | 0.0792077 |
| ASPH | aspartate beta-hydroxylase | 0.0569869 |
| PCBP3 | poly(rC) binding protein 3 | 0.0433196 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0405488 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0398431 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0353722 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0341794 |
| DST | dystonin | 0.0338331 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0334488 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0326471 |
| EFNA5 | ephrin-A5 | 0.0315378 |
| MFF | mitochondrial fission factor | 0.0297409 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0291411 |
| PTGR1 | prostaglandin reductase 1 | 0.0286362 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0284509 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0279807 |
| CTSC | cathepsin C | 0.0272323 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0265639 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0259549 |
| CD109 | CD109 molecule | 0.0254833 |
| TNPO1 | transportin 1 | 0.0254499 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0232676 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0232307 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0231694 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0220205 |
| VMP1 | vacuole membrane protein 1 | 0.0218417 |
| PTEN | phosphatase and tensin homolog | 0.0214472 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0208297 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0203307 |
| MAP1B | microtubule-associated protein 1B | 0.0202341 |
| TUSC3 | tumor suppressor candidate 3 | 0.0200757 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0199843 |
| SLFN5 | schlafen family member 5 | 0.0198729 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0198147 |
| NEK7 | NIMA-related kinase 7 | 0.0193715 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0187973 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.0186371 |
| NRCAM | neuronal cell adhesion molecule | 0.0186092 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0185423 |
| OSMR | oncostatin M receptor | 0.0185218 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0183654 |
| PYGL | phosphorylase, glycogen, liver | 0.0181756 |
| DISP1 | dispatched homolog 1 (Drosophila) | 0.0180857 |
| NTN4 | netrin 4 | 0.0178356 |
| SFPQ | splicing factor proline/glutamine-rich | 0.017814 |
| KYNU | kynureninase | 0.0174927 |
| BDNF | brain-derived neurotrophic factor | 0.0170773 |
| ZBTB41 | zinc finger and BTB domain containing 41 | 0.0168138 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0166615 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0162358 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0159616 |
| MSN | moesin | 0.0158016 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0156112 |
| AOPEP | aminopeptidase O (putative) | 0.0153647 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0153574 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0152359 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.015232 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0150317 |
| EPGN | epithelial mitogen | 0.0145143 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.0144864 |
| EXOC6B | exocyst complex component 6B | 0.0142007 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0140149 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0137118 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0137092 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0134672 |
| CEP112 | centrosomal protein 112kDa | 0.0133475 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0133422 |
| MT2A | metallothionein 2A | 0.0133388 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.0130818 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0130556 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0129769 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0127962 |
| R3HDM2 | R3H domain containing 2 | 0.0126425 |
| ENAH | enabled homolog (Drosophila) | 0.0125962 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0124995 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0124102 |
| INVS | inversin | 0.0122831 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0121205 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0120886 |
| FRMD4B | FERM domain containing 4B | 0.0120639 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0119533 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0115975 |
| TMSB4X | thymosin beta 4, X-linked | 0.0115434 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0115296 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0114862 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0114401 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0113803 |
| ALPK2 | alpha-kinase 2 | 0.0113564 |
| SEPTIN10 | septin 10 | 0.011335 |
| PHF14 | PHD finger protein 14 | 0.0112208 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.011187 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0111566 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0111064 |
| RAB10 | RAB10, member RAS oncogene family | 0.0110357 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.0110137 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0110024 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.210144 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.161715 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.156454 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.140374 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0970741 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0888704 |
| FN1 | fibronectin 1 | -0.0874104 |
| SPAG9 | sperm associated antigen 9 | -0.0804994 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0553885 |
| CDH13 | cadherin 13 | -0.0549923 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0544189 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0482468 |
| TMSB10 | thymosin beta 10 | -0.0480217 |
| PTMA | prothymosin, alpha | -0.0465714 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0464938 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0450363 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0422462 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0415382 |
| ANXA1 | annexin A1 | -0.0414499 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0412895 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0411909 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0408819 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0404741 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0403822 |
| STC1 | stanniocalcin 1 | -0.0400485 |
| MORF4L2 | mortality factor 4 like 2 | -0.0397401 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0377921 |
| PDE10A | phosphodiesterase 10A | -0.0371568 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0361697 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0354551 |
| PGK1 | phosphoglycerate kinase 1 | -0.0345401 |
| GOLGA4 | golgin A4 | -0.0341562 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0337931 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0329334 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.032894 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0325328 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0324666 |
| CANX | calnexin | -0.031892 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0318876 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0317805 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0316481 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0315978 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0314494 |
| NUP58 | nucleoporin 58 | -0.0314451 |
| DNER | delta/notch-like EGF repeat containing | -0.0309039 |
| GNAS | GNAS complex locus | -0.030372 |
| LSAMP | limbic system-associated membrane protein | -0.0301908 |
| NDRG1 | N-myc downstream regulated 1 | -0.0297142 |
| RPS6 | ribosomal protein S6 | -0.0296605 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0292605 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0292513 |
| WDR45B | WD repeat domain 45B | -0.0289598 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0288652 |
| HELZ | helicase with zinc finger | -0.0288616 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0287887 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0284297 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0283943 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.028369 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0283242 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0278528 |
| CTBP2 | C-terminal binding protein 2 | -0.0277135 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0275029 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0272791 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0271136 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.026695 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0262763 |
| YBX3 | Y box binding protein 3 | -0.0261864 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0260322 |
| RBM39 | RNA binding motif protein 39 | -0.0258634 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0258587 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0256503 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0256285 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0255617 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0255532 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0255507 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0250071 |
| COPA | coatomer protein complex, subunit alpha | -0.0248456 |
| RPLP1 | ribosomal protein, large, P1 | -0.0248301 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.024644 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0245468 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0244664 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0242995 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0240648 |
| FAM13A | family with sequence similarity 13, member A | -0.0239818 |
| S100A10 | S100 calcium binding protein A10 | -0.0238428 |
| FTL | ferritin, light polypeptide | -0.0237161 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0236723 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0235306 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0232685 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0232678 |
| ANXA2 | annexin A2 | -0.0231136 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0230821 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0227686 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0226968 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.022616 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0224007 |
| EPHA4 | EPH receptor A4 | -0.0220872 |
| NBEAL1 | neurobeachin-like 1 | -0.021971 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.021936 |
| LAMA1 | laminin, alpha 1 | -0.0218833 |
