| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.10905 |
| EZR | ezrin | 0.107201 |
| POTEF | POTE ankyrin domain family, member F | 0.101001 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0875015 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0804546 |
| GOLGA4 | golgin A4 | 0.07885 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0741687 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0722805 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0705261 |
| RBM39 | RNA binding motif protein 39 | 0.0702699 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0702474 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0682965 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0682599 |
| XPO1 | exportin 1 | 0.0659276 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0647249 |
| TMSB4X | thymosin beta 4, X-linked | 0.0631455 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0622246 |
| GPC6 | glypican 6 | 0.0617525 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.060257 |
| PTK2 | protein tyrosine kinase 2 | 0.0594702 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0586993 |
| ZNF638 | zinc finger protein 638 | 0.0586246 |
| SBF2 | SET binding factor 2 | 0.0584055 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0579552 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0579277 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0575592 |
| NF1 | neurofibromin 1 | 0.056844 |
| USP34 | ubiquitin specific peptidase 34 | 0.0550729 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0541361 |
| ATXN1 | ataxin 1 | 0.0531229 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0518738 |
| RPL19 | ribosomal protein L19 | 0.0513123 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0488365 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0484488 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0479403 |
| RUNX1 | runt-related transcription factor 1 | 0.0474024 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0469513 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0462903 |
| DENND5B | DENN/MADD domain containing 5B | 0.045449 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0440569 |
| SYT1 | synaptotagmin I | 0.0438342 |
| EFNA5 | ephrin-A5 | 0.0435803 |
| VEGFA | vascular endothelial growth factor A | 0.0433799 |
| CANX | calnexin | 0.0432122 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0431079 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0427635 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0419677 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0411283 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0410449 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.041028 |
| TPM4 | tropomyosin 4 | 0.0407213 |
| ERBIN | erbb2 interacting protein | 0.0406582 |
| FTL | ferritin, light polypeptide | 0.0405363 |
| SPAG9 | sperm associated antigen 9 | 0.0397709 |
| ENO1 | enolase 1, (alpha) | 0.0369515 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.03661 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0358047 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0356617 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0355143 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0355057 |
| TXNRD1 | thioredoxin reductase 1 | 0.0352238 |
| APP | amyloid beta (A4) precursor protein | 0.0336764 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0330367 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0328905 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0323381 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0318561 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0310908 |
| LAMC2 | laminin, gamma 2 | 0.0310077 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0302192 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0295712 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0287617 |
| BRD2 | bromodomain containing 2 | 0.0281749 |
| TCF12 | transcription factor 12 | 0.027835 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0271281 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0269123 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0256414 |
| GPHN | gephyrin | 0.0253818 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0251768 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.024306 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0241806 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0240212 |
| USP3 | ubiquitin specific peptidase 3 | 0.0239553 |
| AOPEP | aminopeptidase O (putative) | 0.0236345 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0235563 |
| OGA | O-GlcNAcase | 0.0233496 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0232285 |
| RORA | RAR-related orphan receptor A | 0.0231898 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0223393 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0222572 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0216382 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0213589 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0211788 |
| NBEAL1 | neurobeachin-like 1 | 0.0203563 |
| DSTN | destrin (actin depolymerizing factor) | 0.0201677 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0200478 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0197378 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0193995 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0183549 |
| JMJD1C | jumonji domain containing 1C | 0.0181479 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0171173 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.384679 |
| VIM | vimentin | -0.163175 |
| HMGA2 | high mobility group AT-hook 2 | -0.12474 |
| UBC | ubiquitin C | -0.0941118 |
| LDHA | lactate dehydrogenase A | -0.0940116 |
| PTMA | prothymosin, alpha | -0.085036 |
| TMSB10 | thymosin beta 10 | -0.0812388 |
| CDH13 | cadherin 13 | -0.0763863 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0758056 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0729275 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0728521 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0721597 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0718015 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0712493 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0681202 |
| EGFR | epidermal growth factor receptor | -0.0643811 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0643021 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0640159 |
| STC1 | stanniocalcin 1 | -0.0626574 |
| PGK1 | phosphoglycerate kinase 1 | -0.0614706 |
| PARD3 | par-3 family cell polarity regulator | -0.0610171 |
| NUP58 | nucleoporin 58 | -0.0607649 |
| MT2A | metallothionein 2A | -0.0596996 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0562474 |
| RPS6 | ribosomal protein S6 | -0.0561177 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0551067 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0547949 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0514959 |
| RPL23 | ribosomal protein L23 | -0.0506485 |
| PKM | pyruvate kinase, muscle | -0.0488843 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0486099 |
| RLF | rearranged L-myc fusion | -0.0485368 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0484623 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0462703 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.043637 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0433235 |
| SMYD3 | SET and MYND domain containing 3 | -0.0431536 |
| RPS12 | ribosomal protein S12 | -0.0429794 |
| DST | dystonin | -0.042287 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0414278 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0409444 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0404318 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0392943 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0375111 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0374976 |
| GPATCH2L | G patch domain containing 2-like | -0.0369973 |
| SMAD3 | SMAD family member 3 | -0.0364713 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0361096 |
| COG5 | component of oligomeric golgi complex 5 | -0.0358944 |
| NDRG1 | N-myc downstream regulated 1 | -0.0357634 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0351642 |
| RPS25 | ribosomal protein S25 | -0.0350372 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0344746 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0342364 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0341643 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0325389 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0324761 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0320633 |
| RPS27A | ribosomal protein S27a | -0.0316041 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0313025 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0311488 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0309082 |
| FN1 | fibronectin 1 | -0.0304253 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0303846 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0301471 |
| MAP4 | microtubule-associated protein 4 | -0.029802 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0295324 |
| SETD5 | SET domain containing 5 | -0.0284666 |
| RPS19 | ribosomal protein S19 | -0.0274851 |
| RPL12 | ribosomal protein L12 | -0.0270723 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0262499 |
| HM13 | histocompatibility (minor) 13 | -0.0260087 |
| SECISBP2L | SECIS binding protein 2-like | -0.0259264 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0257754 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0250991 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0250267 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0228094 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0223805 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0220211 |
| RPL5 | ribosomal protein L5 | -0.0218434 |
| COL5A1 | collagen, type V, alpha 1 | -0.0215912 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0211056 |
| RYBP | RING1 and YY1 binding protein | -0.0210842 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0205014 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0201264 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0200283 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0199248 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0198577 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0188561 |
| RPL37A | ribosomal protein L37a | -0.018784 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.01816 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0179107 |
| NEK7 | NIMA-related kinase 7 | -0.0177867 |
| RPS24 | ribosomal protein S24 | -0.0173532 |
| BBX | bobby sox homolog (Drosophila) | -0.0172671 |
| MYO6 | myosin VI | -0.0171793 |
| DIAPH2 | diaphanous-related formin 2 | -0.0167777 |
| KIAA0319L | KIAA0319-like | -0.0164458 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0161984 |
| TLK1 | tousled-like kinase 1 | -0.0157722 |
