| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0637563 |
| JMJD1C | jumonji domain containing 1C | 0.0588236 |
| CENPF | centromere protein F, 350/400kDa | 0.0566984 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0565626 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0553977 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0532267 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0524008 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0518082 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0436788 |
| ZNF292 | zinc finger protein 292 | 0.0414757 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0405538 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0401672 |
| MKI67 | marker of proliferation Ki-67 | 0.0401535 |
| NEK7 | NIMA-related kinase 7 | 0.0400517 |
| RTN4 | reticulon 4 | 0.0399407 |
| PEG10 | paternally expressed 10 | 0.0377537 |
| WDR43 | WD repeat domain 43 | 0.0368809 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0358315 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0350473 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0346173 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0345078 |
| CCNL1 | cyclin L1 | 0.0342 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0331307 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0320725 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0311849 |
| RYBP | RING1 and YY1 binding protein | 0.0308326 |
| RHEB | Ras homolog enriched in brain | 0.0302652 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0302367 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0275465 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0271628 |
| SIK3 | SIK family kinase 3 | 0.0269581 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0269409 |
| NOP58 | NOP58 ribonucleoprotein | 0.0267106 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.026512 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0264368 |
| IPO7 | importin 7 | 0.026074 |
| CENPE | centromere protein E, 312kDa | 0.0258978 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0258856 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0252537 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0251162 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | 0.0249599 |
| RBM39 | RNA binding motif protein 39 | 0.0246235 |
| TPX2 | TPX2, microtubule-associated | 0.0245997 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0244763 |
| RPL4 | ribosomal protein L4 | 0.0244483 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0241314 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0240831 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0238607 |
| HDAC9 | histone deacetylase 9 | 0.0238508 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0237636 |
| USP3 | ubiquitin specific peptidase 3 | 0.0236609 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0235771 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0231827 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0231505 |
| SESN1 | sestrin 1 | 0.0231488 |
| TPR | translocated promoter region, nuclear basket protein | 0.023085 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0230612 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0228027 |
| FAM168A | family with sequence similarity 168, member A | 0.0227925 |
| KIF4A | kinesin family member 4A | 0.0227385 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0224678 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0224625 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0224544 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0219186 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0218835 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0218763 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0218728 |
| ZNF644 | zinc finger protein 644 | 0.0217822 |
| GOLGB1 | golgin B1 | 0.0216416 |
| PDS5B | PDS5 cohesin associated factor B | 0.0215792 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0215479 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0212857 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 0.0211712 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0209832 |
| CDK6 | cyclin-dependent kinase 6 | 0.0209223 |
| VEGFA | vascular endothelial growth factor A | 0.0207829 |
| CNN3 | calponin 3, acidic | 0.0207822 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0207283 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.0206577 |
| FIGN | fidgetin | 0.0206238 |
| RBM27 | RNA binding motif protein 27 | 0.0205722 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0205472 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0204687 |
| PHF3 | PHD finger protein 3 | 0.0204342 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0203406 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0202526 |
| DEK | DEK proto-oncogene | 0.0200992 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0200856 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.0199561 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0199009 |
| RBM25 | RNA binding motif protein 25 | 0.0198866 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0198657 |
| AFDN | afadin, adherens junction formation factor | 0.019677 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0195692 |
| MB21D2 | Mab-21 domain containing 2 | 0.0191482 |
| MTMR3 | myotubularin related protein 3 | 0.0190587 |
| FAM133B | family with sequence similarity 133, member B | 0.0190529 |
| SET | SET nuclear proto-oncogene | 0.0190308 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0190013 |
| TPM3 | tropomyosin 3 | 0.0187726 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | -0.257855 |
| CADM2 | cell adhesion molecule 2 | -0.106432 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.105386 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0770281 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0736471 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0722102 |
| TMSB10 | thymosin beta 10 | -0.0696115 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0684216 |
| RAD51B | RAD51 paralog B | -0.0615212 |
| GPC3 | glypican 3 | -0.0603515 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0598173 |
| VIM | vimentin | -0.0584032 |
| LRRC4C | leucine rich repeat containing 4C | -0.0571478 |
| CALR | calreticulin | -0.0569579 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0546295 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0509262 |
| SPAG9 | sperm associated antigen 9 | -0.0486028 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0482826 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0479755 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0476495 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0458611 |
| H1-0 | H1.0 linker histone | -0.0450043 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0446394 |
| B2M | beta-2-microglobulin | -0.0439286 |
| COL3A1 | collagen, type III, alpha 1 | -0.0426217 |
| PTMA | prothymosin, alpha | -0.0425502 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0406293 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0395425 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0393492 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0387853 |
| NPAS3 | neuronal PAS domain protein 3 | -0.037746 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0377388 |
| ENO1 | enolase 1, (alpha) | -0.037414 |
| COL1A2 | collagen, type I, alpha 2 | -0.0361754 |
| MAP4 | microtubule-associated protein 4 | -0.0357246 |
| PCDH9 | protocadherin 9 | -0.0355528 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0352035 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.035191 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0345571 |
| LYST | lysosomal trafficking regulator | -0.0340906 |
| RPS8 | ribosomal protein S8 | -0.0337911 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0334345 |
| NRG1 | neuregulin 1 | -0.0333728 |
| RIGI | RNA sensor RIG-I | -0.0326771 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0310633 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0308669 |
| RPS6 | ribosomal protein S6 | -0.0303032 |
| NF1 | neurofibromin 1 | -0.0302246 |
| RPS3 | ribosomal protein S3 | -0.0301989 |
| THOC2 | THO complex 2 | -0.0301198 |
| ATXN1 | ataxin 1 | -0.029449 |
| TMSB4X | thymosin beta 4, X-linked | -0.0293979 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0293802 |
| GOLGA4 | golgin A4 | -0.0290923 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.028899 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0287319 |
| RPS16 | ribosomal protein S16 | -0.0286632 |
| PHIP | pleckstrin homology domain interacting protein | -0.0286307 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0280939 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0278614 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.027848 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0277369 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0276228 |
| FTL | ferritin, light polypeptide | -0.0274109 |
| PGK1 | phosphoglycerate kinase 1 | -0.02723 |
| RASAL2 | RAS protein activator like 2 | -0.0268843 |
| NDRG1 | N-myc downstream regulated 1 | -0.0267364 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0266189 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0265885 |
| STAG2 | stromal antigen 2 | -0.0265634 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0261881 |
| MED13L | mediator complex subunit 13-like | -0.0260603 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0259143 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0257446 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | -0.0255783 |
| RPL37 | ribosomal protein L37 | -0.0251012 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0250682 |
| RPL28 | ribosomal protein L28 | -0.0249558 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0246425 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0244403 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.024414 |
| MEIS2 | Meis homeobox 2 | -0.0241837 |
| MPG | N-methylpurine-DNA glycosylase | -0.0240782 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0240459 |
| USP34 | ubiquitin specific peptidase 34 | -0.0239247 |
| MED12L | mediator complex subunit 12-like | -0.0238212 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0237846 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0237503 |
| UTRN | utrophin | -0.0237419 |
| PRR16 | proline rich 16 | -0.0236252 |
| RPL12 | ribosomal protein L12 | -0.023388 |
| RPLP1 | ribosomal protein, large, P1 | -0.0232389 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0231999 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0228069 |
| LDHA | lactate dehydrogenase A | -0.0227475 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0227448 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0226661 |
| PLPP1 | phospholipid phosphatase 1 | -0.0226245 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0225566 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0224952 |
