| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.137806 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0706165 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0651424 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0615652 |
| VMP1 | vacuole membrane protein 1 | 0.0517291 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0481706 |
| ACTN4 | actinin, alpha 4 | 0.0459486 |
| ASPH | aspartate beta-hydroxylase | 0.0457537 |
| TXNRD1 | thioredoxin reductase 1 | 0.0439009 |
| RTN4 | reticulon 4 | 0.0420448 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0399098 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0382459 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0378727 |
| CD44 | CD44 molecule (Indian blood group) | 0.0374055 |
| CARD18 | caspase recruitment domain family, member 18 | 0.037227 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0371147 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0369621 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0354151 |
| ZNF780B | zinc finger protein 780B | 0.0341032 |
| ITGB5 | integrin, beta 5 | 0.0334257 |
| SMYD3 | SET and MYND domain containing 3 | 0.0334172 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0322347 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0321579 |
| FHL2 | four and a half LIM domains 2 | 0.0313189 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0310237 |
| EFNA5 | ephrin-A5 | 0.0309803 |
| MCL1 | myeloid cell leukemia 1 | 0.03005 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0298108 |
| JMJD1C | jumonji domain containing 1C | 0.0291797 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0282726 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0261336 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0258416 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0252941 |
| TMEM41B | transmembrane protein 41B | 0.0232334 |
| EXOC6B | exocyst complex component 6B | 0.0225959 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0225398 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0224421 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0221144 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0218421 |
| ZFP36 | ZFP36 ring finger protein | 0.0210146 |
| FAM3C | family with sequence similarity 3, member C | 0.0207378 |
| OSMR | oncostatin M receptor | 0.020416 |
| BMP6 | bone morphogenetic protein 6 | 0.0203033 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0202399 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0201968 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0201385 |
| ATXN1 | ataxin 1 | 0.0198932 |
| PRELID2 | PRELI domain containing 2 | 0.0198927 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0198279 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0195668 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0195173 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0193661 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0188436 |
| PHF14 | PHD finger protein 14 | 0.0187033 |
| ITGAV | integrin, alpha V | 0.0185333 |
| LUZP1 | leucine zipper protein 1 | 0.0179363 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0177687 |
| ANO6 | anoctamin 6 | 0.0174112 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.0173782 |
| FOSL1 | FOS-like antigen 1 | 0.017311 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0173011 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0168986 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0168542 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.0161343 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0158776 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0156256 |
| PTEN | phosphatase and tensin homolog | 0.0155707 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0155429 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0155303 |
| BCL2L1 | BCL2-like 1 | 0.0153643 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0153629 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0151445 |
| MOSMO | modulator of smoothened | 0.0147847 |
| DNMBP | dynamin binding protein | 0.0146267 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0145835 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0145104 |
| METTL15 | methyltransferase like 15 | 0.0145045 |
| ZNF644 | zinc finger protein 644 | 0.0144434 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0144091 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0140236 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0139066 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0138883 |
| SATB2 | SATB homeobox 2 | 0.0137248 |
| FAM120B | family with sequence similarity 120B | 0.0137107 |
| DNHD1 | dynein heavy chain domain 1 | 0.0136765 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0136604 |
| ATM | ATM serine/threonine kinase | 0.0136135 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0135906 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0135081 |
| BPTF | bromodomain PHD finger transcription factor | 0.0135023 |
| RASAL2 | RAS protein activator like 2 | 0.0133922 |
| NABP1 | nucleic acid binding protein 1 | 0.0133584 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.0133016 |
| ARRDC3 | arrestin domain containing 3 | 0.0130557 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0129051 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0128594 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0127833 |
| CAB39 | calcium binding protein 39 | 0.0126321 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.0125899 |
| YAP1 | Yes-associated protein 1 | 0.0125687 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.202254 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.19433 |
| PTMA | prothymosin, alpha | -0.182141 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.167846 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.116803 |
| FBL | fibrillarin | -0.116579 |
| RPS16 | ribosomal protein S16 | -0.116445 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.115469 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114846 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0779338 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0772241 |
| CANX | calnexin | -0.0603272 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.059674 |
| AHNAK | AHNAK nucleoprotein | -0.0543717 |
| ACTG1 | actin gamma 1 | -0.0520174 |
| S100A6 | S100 calcium binding protein A6 | -0.0453231 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0451608 |
| SPAG9 | sperm associated antigen 9 | -0.0450435 |
| ENO1 | enolase 1, (alpha) | -0.0421807 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0412088 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0404545 |
| FTL | ferritin, light polypeptide | -0.0402921 |
| TMSB10 | thymosin beta 10 | -0.0393234 |
| FMNL2 | formin-like 2 | -0.0389979 |
| ADM | adrenomedullin | -0.0374624 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0373761 |
| KPNB1 | karyopherin (importin) beta 1 | -0.037345 |
| LDHA | lactate dehydrogenase A | -0.037032 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0360737 |
| GOLGA4 | golgin A4 | -0.0358041 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0351587 |
| PGK1 | phosphoglycerate kinase 1 | -0.0345302 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0345114 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0342688 |
| MYOF | myoferlin | -0.0341742 |
| SEPTIN7 | septin 7 | -0.0340585 |
| MORF4L2 | mortality factor 4 like 2 | -0.0336549 |
| CALR | calreticulin | -0.0334398 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0332438 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0331466 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0328059 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0325938 |
| PKM | pyruvate kinase, muscle | -0.0322945 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0316317 |
| RNF220 | ring finger protein 220 | -0.0306122 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0304684 |
| NAV2 | neuron navigator 2 | -0.0303587 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0299526 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0292758 |
| ANXA2 | annexin A2 | -0.0281938 |
| YBX1 | Y box binding protein 1 | -0.0279498 |
| RPL35A | ribosomal protein L35a | -0.0279457 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0278056 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0269838 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0268979 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0268791 |
| CAVIN1 | caveolae associated protein 1 | -0.0268349 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0267178 |
| GNAS | GNAS complex locus | -0.0266762 |
| H1-0 | H1.0 linker histone | -0.0264827 |
| SNX14 | sorting nexin 14 | -0.0263575 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.026307 |
| WDR45B | WD repeat domain 45B | -0.0261108 |
| CTSD | cathepsin D | -0.0257741 |
| RPS24 | ribosomal protein S24 | -0.0252633 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0234215 |
| TMEM123 | transmembrane protein 123 | -0.0231714 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0229981 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0228955 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0228204 |
| RPLP0 | ribosomal protein, large, P0 | -0.0221654 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0220463 |
| RPS8 | ribosomal protein S8 | -0.0219784 |
| CD109 | CD109 molecule | -0.0218077 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0217906 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0212903 |
| RPS3 | ribosomal protein S3 | -0.0209492 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0208752 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0207901 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0206943 |
| WASF2 | WAS protein family, member 2 | -0.0206798 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0206398 |
| CTBP2 | C-terminal binding protein 2 | -0.0205011 |
| LMNA | lamin A/C | -0.0204854 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0204286 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0203281 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.020265 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0201776 |
| RPS27A | ribosomal protein S27a | -0.0201133 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0201091 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.020047 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.019958 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0199514 |
| HMGA1 | high mobility group AT-hook 1 | -0.0199249 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0192216 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0191878 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0191672 |
| HM13 | histocompatibility (minor) 13 | -0.0190395 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0190212 |
| ANLN | anillin, actin binding protein | -0.0188711 |
