| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.12807 |
| VEGFA | vascular endothelial growth factor A | 0.0978354 |
| B2M | beta-2-microglobulin | 0.0855819 |
| CD44 | CD44 molecule (Indian blood group) | 0.0739789 |
| MT2A | metallothionein 2A | 0.0617333 |
| TGM2 | transglutaminase 2 | 0.0544643 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0503028 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0476026 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0457065 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0447343 |
| ASPH | aspartate beta-hydroxylase | 0.0429419 |
| AFAP1 | actin filament associated protein 1 | 0.0412888 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0398268 |
| VIM | vimentin | 0.0386433 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.03861 |
| HMGA2 | high mobility group AT-hook 2 | 0.0385897 |
| MSN | moesin | 0.0372034 |
| SMAD3 | SMAD family member 3 | 0.035997 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0356437 |
| POTEF | POTE ankyrin domain family, member F | 0.0355833 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0346277 |
| HPCAL1 | hippocalcin-like 1 | 0.0337305 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0335713 |
| FAM20C | family with sequence similarity 20, member C | 0.0330892 |
| NAV2 | neuron navigator 2 | 0.0316308 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0311244 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0301591 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0296813 |
| TMF1 | TATA element modulatory factor 1 | 0.0291127 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0290957 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0290957 |
| CDCP1 | CUB domain containing protein 1 | 0.0289083 |
| CDK19 | cyclin-dependent kinase 19 | 0.0286011 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0281195 |
| MKI67 | marker of proliferation Ki-67 | 0.0276042 |
| SSH1 | slingshot protein phosphatase 1 | 0.0271192 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0255368 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0255316 |
| TXNRD1 | thioredoxin reductase 1 | 0.0248427 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0243045 |
| RPS17 | ribosomal protein S17 | 0.0242613 |
| KYNU | kynureninase | 0.0241066 |
| RPS13 | ribosomal protein S13 | 0.023403 |
| RPS6 | ribosomal protein S6 | 0.0232619 |
| HLA-B | major histocompatibility complex, class I, B | 0.0231118 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0230518 |
| ZNF148 | zinc finger protein 148 | 0.0229728 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0228736 |
| CENPF | centromere protein F, 350/400kDa | 0.0227197 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0226902 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0224864 |
| SVIL | supervillin | 0.022079 |
| PTK2 | protein tyrosine kinase 2 | 0.022047 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0216134 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0214883 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0213169 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0212608 |
| FLNB | filamin B, beta | 0.0210416 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0210404 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0209196 |
| CENPE | centromere protein E, 312kDa | 0.0208915 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.020856 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.02046 |
| PDE10A | phosphodiesterase 10A | 0.0204164 |
| STK4 | serine/threonine kinase 4 | 0.0203443 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0202772 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0202495 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0201993 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0201866 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0200714 |
| KIF4A | kinesin family member 4A | 0.020018 |
| ANGPTL4 | angiopoietin-like 4 | 0.0199705 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0198416 |
| RLIM | ring finger protein, LIM domain interacting | 0.0196714 |
| SMOX | spermine oxidase | 0.0195942 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0193212 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0189166 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0185179 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0184931 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0182132 |
| TPM3 | tropomyosin 3 | 0.0181361 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0180102 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0180009 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0179772 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0179661 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0178452 |
| OSMR | oncostatin M receptor | 0.0177132 |
| ANLN | anillin, actin binding protein | 0.0177089 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0176963 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0176576 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0175108 |
| PHF3 | PHD finger protein 3 | 0.0174732 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0174552 |
| COG5 | component of oligomeric golgi complex 5 | 0.017429 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0173911 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0173534 |
| MX1 | MX dynamin-like GTPase 1 | 0.0172985 |
| SP3 | Sp3 transcription factor | 0.0171067 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0169651 |
| GRAMD1B | GRAM domain containing 1B | 0.016716 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.287091 |
| COL1A1 | collagen, type I, alpha 1 | -0.131751 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.125906 |
| CDH13 | cadherin 13 | -0.113247 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0942498 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0902668 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0902609 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0824642 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0792591 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0777588 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0732419 |
| MYOF | myoferlin | -0.0639691 |
| ANXA2 | annexin A2 | -0.0625618 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0621932 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0605025 |
| LOXL2 | lysyl oxidase-like 2 | -0.0598202 |
| COL5A1 | collagen, type V, alpha 1 | -0.0591194 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0572655 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0571755 |
| MMP12 | matrix metallopeptidase 12 | -0.0570486 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0556137 |
| CADM1 | cell adhesion molecule 1 | -0.0543775 |
| FHIT | fragile histidine triad | -0.0538168 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0514123 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0502346 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0494384 |
| CD109 | CD109 molecule | -0.0479623 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0477681 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0476032 |
| AHNAK | AHNAK nucleoprotein | -0.0475376 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0464779 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.046187 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0460086 |
| RBM39 | RNA binding motif protein 39 | -0.0459958 |
| NDRG1 | N-myc downstream regulated 1 | -0.0456743 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0450797 |
| FBXO32 | F-box protein 32 | -0.0448653 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0439364 |
| SP100 | SP100 nuclear antigen | -0.0435941 |
| TMEM178B | transmembrane protein 178B | -0.0433581 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0432201 |
| JUN | jun proto-oncogene | -0.0432116 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0430101 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0424115 |
| TMSB10 | thymosin beta 10 | -0.0423826 |
| H1-0 | H1.0 linker histone | -0.041874 |
| MEF2A | myocyte enhancer factor 2A | -0.0418141 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0413609 |
| GNAS | GNAS complex locus | -0.0404068 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0403533 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0399872 |
| RND3 | Rho family GTPase 3 | -0.0376764 |
| RAB1A | RAB1A, member RAS oncogene family | -0.037453 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0372288 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0364054 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0360651 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0358808 |
| RYBP | RING1 and YY1 binding protein | -0.0354354 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.035345 |
| SEC24D | SEC24 family member D | -0.0350614 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0349052 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0348002 |
| FBN1 | fibrillin 1 | -0.0347186 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0347045 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0346496 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.034605 |
| TMEM263 | transmembrane protein 263 | -0.0345301 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0344444 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0343292 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0342875 |
| EGFR | epidermal growth factor receptor | -0.0342281 |
| HDAC9 | histone deacetylase 9 | -0.0340781 |
| FRMD4A | FERM domain containing 4A | -0.0337953 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.033446 |
| COL1A2 | collagen, type I, alpha 2 | -0.0333377 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0328714 |
| FBXO11 | F-box protein 11 | -0.0325291 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0321197 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0320572 |
| INHBA | inhibin, beta A | -0.0320142 |
| IER3 | immediate early response 3 | -0.0312473 |
| NAV1 | neuron navigator 1 | -0.0309171 |
| SQSTM1 | sequestosome 1 | -0.0308527 |
| RAD51B | RAD51 paralog B | -0.0306846 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0305991 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0304451 |
| MORF4L2 | mortality factor 4 like 2 | -0.0300215 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0296103 |
| XAF1 | XIAP associated factor 1 | -0.0294896 |
| FUS | FUS RNA binding protein | -0.029353 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0293006 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0291778 |
| FMNL2 | formin-like 2 | -0.0290215 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0287345 |
| VCAN | versican | -0.0282777 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0280734 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0280312 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0279751 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0277212 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0276564 |
