| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | 0.106361 |
| SNTG1 | syntrophin, gamma 1 | 0.0727163 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0721764 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0599326 |
| GPC6 | glypican 6 | 0.0528944 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0475118 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0438712 |
| NRG1 | neuregulin 1 | 0.0430259 |
| CNKSR3 | CNKSR family member 3 | 0.0359004 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.033182 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | 0.0283152 |
| SIK3 | SIK family kinase 3 | 0.0267078 |
| SMYD3 | SET and MYND domain containing 3 | 0.0265901 |
| EFNA5 | ephrin-A5 | 0.0257024 |
| HDAC9 | histone deacetylase 9 | 0.0256889 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0253927 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0252522 |
| AGMO | alkylglycerol monooxygenase | 0.0252377 |
| RIT2 | Ras-like without CAAX 2 | 0.0240865 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0235199 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0234252 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.0233606 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.0231208 |
| PCBP3 | poly(rC) binding protein 3 | 0.022977 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0225308 |
| GON4L | gon-4-like (C. elegans) | 0.0218559 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0216526 |
| TSPYL2 | TSPY-like 2 | 0.0216001 |
| AOPEP | aminopeptidase O (putative) | 0.0209773 |
| JAZF1 | JAZF zinc finger 1 | 0.020903 |
| GPC5 | glypican 5 | 0.0206464 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0205714 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0204964 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.0200317 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0199448 |
| DENND5B | DENN/MADD domain containing 5B | 0.0197843 |
| ZFHX3 | zinc finger homeobox 3 | 0.0196999 |
| GPATCH2L | G patch domain containing 2-like | 0.019662 |
| PCDH9 | protocadherin 9 | 0.0195978 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0193977 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0188803 |
| MGA | MGA, MAX dimerization protein | 0.0188284 |
| TMSB4X | thymosin beta 4, X-linked | 0.0186602 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 | 0.0184861 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0180179 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.017924 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0176281 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0174395 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0174014 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0170799 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0170781 |
| JAM3 | junctional adhesion molecule 3 | 0.0170614 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0170228 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0168019 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.016783 |
| BCL2 | B-cell CLL/lymphoma 2 | 0.0166377 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0166017 |
| PALLD | palladin, cytoskeletal associated protein | 0.0164968 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.016438 |
| TASP1 | taspase, threonine aspartase, 1 | 0.0163247 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0163115 |
| RORA | RAR-related orphan receptor A | 0.0163019 |
| DISC1 | disrupted in schizophrenia 1 | 0.0160607 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0158656 |
| ABCA13 | ATP-binding cassette, sub-family A (ABC1), member 13 | 0.0158652 |
| RPL4 | ribosomal protein L4 | 0.0158586 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0158479 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0155516 |
| NF1 | neurofibromin 1 | 0.0155178 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0153948 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0152077 |
| TRAPPC10 | trafficking protein particle complex 10 | 0.0151991 |
| ZNF644 | zinc finger protein 644 | 0.0150762 |
| MEF2A | myocyte enhancer factor 2A | 0.015049 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0149575 |
| CELF4 | CUGBP, Elav-like family member 4 | 0.0146334 |
| HMBOX1 | homeobox containing 1 | 0.0145713 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0145015 |
| CDK13 | cyclin-dependent kinase 13 | 0.0145003 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0144502 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0144373 |
| RNF169 | ring finger protein 169 | 0.0143657 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0143438 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0142644 |
| TPP2 | tripeptidyl peptidase II | 0.0142362 |
| SPPL3 | signal peptide peptidase like 3 | 0.0141703 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.014149 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | 0.0141237 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0139941 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.0138465 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0138137 |
| YY1AP1 | YY1 associated protein 1 | 0.0137097 |
| NBEA | neurobeachin | 0.0137044 |
| DACH1 | dachshund family transcription factor 1 | 0.0137023 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase | 0.0136448 |
| MMP26 | matrix metallopeptidase 26 | 0.0136394 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.0136298 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0136294 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.013541 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | 0.0134978 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.19198 |
| VGF | VGF nerve growth factor inducible | -0.189049 |
| PDE10A | phosphodiesterase 10A | -0.181373 |
| PTMA | prothymosin, alpha | -0.143881 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.137999 |
| ENO1 | enolase 1, (alpha) | -0.132847 |
| TENM1 | teneurin transmembrane protein 1 | -0.108457 |
| MT2A | metallothionein 2A | -0.107183 |
| CALCA | calcitonin-related polypeptide alpha | -0.100991 |
| FTL | ferritin, light polypeptide | -0.0996675 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0750456 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0696299 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0664316 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0586698 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0571124 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0538162 |
| TMSB10 | thymosin beta 10 | -0.0479645 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.047609 |
| RPS3 | ribosomal protein S3 | -0.0460901 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0457183 |
| RPS8 | ribosomal protein S8 | -0.0455825 |
| CPE | carboxypeptidase E | -0.044448 |
| PKM | pyruvate kinase, muscle | -0.0442355 |
| PGK1 | phosphoglycerate kinase 1 | -0.0439779 |
| RPS6 | ribosomal protein S6 | -0.0439627 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0439416 |
| STC1 | stanniocalcin 1 | -0.0436605 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0433229 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0430064 |
| S100A9 | S100 calcium binding protein A9 | -0.0426271 |
| RPS21 | ribosomal protein S21 | -0.0407286 |
| NDRG1 | N-myc downstream regulated 1 | -0.0403092 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0399483 |
| RPL8 | ribosomal protein L8 | -0.0397324 |
| RPLP1 | ribosomal protein, large, P1 | -0.0393748 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.039017 |
| MCL1 | myeloid cell leukemia 1 | -0.0389134 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0388824 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0385748 |
| ZNF292 | zinc finger protein 292 | -0.0378536 |
| PEG10 | paternally expressed 10 | -0.0375298 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0373596 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.037171 |
| CENPF | centromere protein F, 350/400kDa | -0.0370798 |
| RNF213 | ring finger protein 213 | -0.0370158 |
| B2M | beta-2-microglobulin | -0.0364019 |
| RPL19 | ribosomal protein L19 | -0.0361581 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.035445 |
| POTEF | POTE ankyrin domain family, member F | -0.0350513 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0348835 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0346964 |
| RPL35 | ribosomal protein L35 | -0.0345627 |
| RPL11 | ribosomal protein L11 | -0.034445 |
| RPS19 | ribosomal protein S19 | -0.0341323 |
| MT1X | metallothionein 1X | -0.03305 |
| RPL23 | ribosomal protein L23 | -0.0320879 |
| RPS16 | ribosomal protein S16 | -0.031908 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0316815 |
| IRS2 | insulin receptor substrate 2 | -0.0316603 |
| CNTNAP2 | contactin associated protein-like 2 | -0.0316594 |
| RTN4 | reticulon 4 | -0.0314996 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0311843 |
| RPL37A | ribosomal protein L37a | -0.0309262 |
| SIK2 | salt-inducible kinase 2 | -0.0308281 |
| NCKAP5 | NCK-associated protein 5 | -0.0307797 |
| WDR45B | WD repeat domain 45B | -0.0299212 |
| RPL12 | ribosomal protein L12 | -0.029902 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0295697 |
| RPL31 | ribosomal protein L31 | -0.0293709 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0289535 |
| EGR1 | early growth response 1 | -0.0289374 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0288675 |
| RPL7A | ribosomal protein L7a | -0.0284032 |
| SEPTIN7 | septin 7 | -0.0283674 |
| FGF14 | fibroblast growth factor 14 | -0.0283113 |
| DSTN | destrin (actin depolymerizing factor) | -0.0282795 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0280896 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0274812 |
| UBB | ubiquitin B | -0.0271766 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0269711 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0267994 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0265045 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0264379 |
| RACK1 | receptor for activated C kinase 1 | -0.026299 |
| RPS5 | ribosomal protein S5 | -0.0258687 |
| RPL37 | ribosomal protein L37 | -0.025815 |
| RPL32 | ribosomal protein L32 | -0.0258137 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0256297 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.025493 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0250349 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0249354 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.0248878 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0248766 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0248523 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0247623 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0246597 |
| RPLP0 | ribosomal protein, large, P0 | -0.0244728 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0244275 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0242847 |
| LDHA | lactate dehydrogenase A | -0.0242554 |
