| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0574111 |
| TMSB4X | thymosin beta 4, X-linked | 0.0502812 |
| TXNRD1 | thioredoxin reductase 1 | 0.0481039 |
| POTEF | POTE ankyrin domain family, member F | 0.0475787 |
| CCNL1 | cyclin L1 | 0.0468797 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0453651 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0453037 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.041865 |
| RPL3 | ribosomal protein L3 | 0.0418426 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0410402 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0381806 |
| CD47 | CD47 molecule | 0.0349228 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0311177 |
| B2M | beta-2-microglobulin | 0.030365 |
| PRELID2 | PRELI domain containing 2 | 0.0297807 |
| NUP58 | nucleoporin 58 | 0.0297272 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0294438 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0288359 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0276008 |
| VEGFA | vascular endothelial growth factor A | 0.0270506 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0269057 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0268801 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0263078 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0256744 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0246304 |
| BRD2 | bromodomain containing 2 | 0.0245044 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0238933 |
| TMEM65 | transmembrane protein 65 | 0.0233977 |
| ENO1 | enolase 1, (alpha) | 0.0232252 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0218733 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0218241 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0212179 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0212081 |
| LOXL3 | lysyl oxidase-like 3 | 0.0211896 |
| CLU | clusterin | 0.021157 |
| EXOC6B | exocyst complex component 6B | 0.0206065 |
| MATR3 | matrin 3 | 0.0206036 |
| YTHDC1 | YTH domain containing 1 | 0.0204209 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0202115 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0200578 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.019978 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0199471 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0198145 |
| MSN | moesin | 0.0197551 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0194313 |
| MACROD2 | MACRO domain containing 2 | 0.0193025 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0191893 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0191812 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.0186784 |
| APP | amyloid beta (A4) precursor protein | 0.0182515 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.018131 |
| YAP1 | Yes-associated protein 1 | 0.0180938 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.017767 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0176687 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0175639 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0175019 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0174929 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0174406 |
| ZNF608 | zinc finger protein 608 | 0.0173626 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0173119 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0172745 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0172178 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0171978 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0170972 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0170064 |
| PCM1 | pericentriolar material 1 | 0.0169142 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0169098 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0168924 |
| CEP250 | centrosomal protein 250kDa | 0.0167441 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0167036 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0165647 |
| PCBP2 | poly(rC) binding protein 2 | 0.0165341 |
| PTK2 | protein tyrosine kinase 2 | 0.0165195 |
| PTEN | phosphatase and tensin homolog | 0.0164716 |
| SFTPA2 | surfactant protein A2 | 0.0164319 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0163662 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0163427 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0162436 |
| ZNF292 | zinc finger protein 292 | 0.016222 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0160723 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0159647 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0157974 |
| TPM3 | tropomyosin 3 | 0.0157953 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0157344 |
| CEP192 | centrosomal protein 192kDa | 0.0157049 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0156396 |
| EFNA5 | ephrin-A5 | 0.0155728 |
| ZNF160 | zinc finger protein 160 | 0.0152176 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0151979 |
| PYGB | phosphorylase, glycogen; brain | 0.0150703 |
| ARRDC3 | arrestin domain containing 3 | 0.0150327 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0149884 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0149135 |
| ZNF638 | zinc finger protein 638 | 0.0148097 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0146852 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0146226 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0145891 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 | 0.0145565 |
| INSIG2 | insulin induced gene 2 | 0.0144009 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0143676 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.247042 |
| PTMA | prothymosin, alpha | -0.236347 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.117783 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.107406 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0976942 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0908463 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0893815 |
| FOXP1 | forkhead box P1 | -0.0866374 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0714395 |
| ACTG1 | actin gamma 1 | -0.0647456 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0638515 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0580992 |
| BMP10 | bone morphogenetic protein 10 | -0.0563123 |
| RPS8 | ribosomal protein S8 | -0.054515 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0527367 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0491024 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0480613 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0475911 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0459899 |
| CCND1 | cyclin D1 | -0.0441498 |
| MKI67 | marker of proliferation Ki-67 | -0.0426093 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0422333 |
| AHNAK | AHNAK nucleoprotein | -0.0411922 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0390971 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0384148 |
| RPL35A | ribosomal protein L35a | -0.0382609 |
| EGFR | epidermal growth factor receptor | -0.0375312 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0371239 |
| RPS24 | ribosomal protein S24 | -0.0369992 |
| RPS6 | ribosomal protein S6 | -0.0369516 |
| TJP1 | tight junction protein 1 | -0.0364533 |
| FUS | FUS RNA binding protein | -0.0359548 |
| VCL | vinculin | -0.0354411 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0351849 |
| MYOF | myoferlin | -0.0349734 |
| RRBP1 | ribosome binding protein 1 | -0.0340173 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0339154 |
| GLI3 | GLI family zinc finger 3 | -0.0338293 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.032371 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0321813 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0320038 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0309674 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.030841 |
| HDAC9 | histone deacetylase 9 | -0.0305772 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0303037 |
| CENPF | centromere protein F, 350/400kDa | -0.030244 |
| CUX1 | cut-like homeobox 1 | -0.0294292 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0292789 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0288152 |
| RPL12 | ribosomal protein L12 | -0.0282595 |
| DIAPH3 | diaphanous-related formin 3 | -0.0278708 |
| HMGB1 | high mobility group box 1 | -0.0278268 |
| PDE7B | phosphodiesterase 7B | -0.0276581 |
| RPL34 | ribosomal protein L34 | -0.0275579 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0272691 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0271391 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0271065 |
| NF1 | neurofibromin 1 | -0.0269017 |
| TBCA | tubulin folding cofactor A | -0.0264029 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0262758 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0260208 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.025746 |
| RPL9 | ribosomal protein L9 | -0.025614 |
| RPLP1 | ribosomal protein, large, P1 | -0.0253281 |
| SEC24D | SEC24 family member D | -0.025205 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0248615 |
| S100A4 | S100 calcium binding protein A4 | -0.024623 |
| GLI2 | GLI family zinc finger 2 | -0.0244731 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0243199 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0240343 |
| DEK | DEK proto-oncogene | -0.0239345 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0238967 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0237782 |
| GPATCH8 | G patch domain containing 8 | -0.0236567 |
| RPS25 | ribosomal protein S25 | -0.0234545 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0232612 |
| RPLP2 | ribosomal protein, large, P2 | -0.0232462 |
| TPX2 | TPX2, microtubule-associated | -0.0232393 |
| RPL32 | ribosomal protein L32 | -0.0230151 |
| RPL7A | ribosomal protein L7a | -0.0228991 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0228101 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0227645 |
| PKP4 | plakophilin 4 | -0.0223504 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0223479 |
| NBEA | neurobeachin | -0.0221538 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | -0.0218655 |
| S100A10 | S100 calcium binding protein A10 | -0.0216798 |
| RIGI | RNA sensor RIG-I | -0.0214816 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0214667 |
| AHI1 | Abelson helper integration site 1 | -0.0213913 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0213076 |
| CDK13 | cyclin-dependent kinase 13 | -0.0212134 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0211609 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.0210175 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0210041 |
| RPS23 | ribosomal protein S23 | -0.0209795 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0209229 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0208573 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0208031 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0207322 |
