| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vitamin K4_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.170915 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.12309 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0853728 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.074207 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0640186 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0636802 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0613003 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0595797 |
| VMP1 | vacuole membrane protein 1 | 0.0497755 |
| MSN | moesin | 0.0479914 |
| MKI67 | marker of proliferation Ki-67 | 0.0475613 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.045319 |
| B2M | beta-2-microglobulin | 0.0451785 |
| ARRDC3 | arrestin domain containing 3 | 0.0444685 |
| VCL | vinculin | 0.0432526 |
| CENPF | centromere protein F, 350/400kDa | 0.0431876 |
| CCNL1 | cyclin L1 | 0.0413989 |
| FN1 | fibronectin 1 | 0.0390111 |
| KYNU | kynureninase | 0.0362883 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0320422 |
| FLOT1 | flotillin 1 | 0.0307159 |
| TPM3 | tropomyosin 3 | 0.0292196 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0291181 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0288534 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0280654 |
| TXNIP | thioredoxin interacting protein | 0.0268062 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.026783 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0264891 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0255908 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0255111 |
| SDC4 | syndecan 4 | 0.024807 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0247849 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0245966 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0245759 |
| MCL1 | myeloid cell leukemia 1 | 0.0241627 |
| TGM2 | transglutaminase 2 | 0.0238491 |
| TXNRD1 | thioredoxin reductase 1 | 0.0230147 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0224074 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0222949 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0210246 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0198203 |
| DIAPH3 | diaphanous-related formin 3 | 0.0197991 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0194236 |
| TPX2 | TPX2, microtubule-associated | 0.0193373 |
| MX1 | MX dynamin-like GTPase 1 | 0.0192949 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0192819 |
| POTEF | POTE ankyrin domain family, member F | 0.0191925 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0189217 |
| PCBP2 | poly(rC) binding protein 2 | 0.017802 |
| ADAR | adenosine deaminase, RNA-specific | 0.0175153 |
| LDHA | lactate dehydrogenase A | 0.0172278 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0168966 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0167304 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.01667 |
| COL1A2 | collagen, type I, alpha 2 | 0.0163903 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0162731 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0159473 |
| DSPP | dentin sialophosphoprotein | 0.0156908 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0156598 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0154361 |
| NONO | non-POU domain containing, octamer-binding | 0.0152566 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0151614 |
| KIF11 | kinesin family member 11 | 0.0151071 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0150677 |
| XPO1 | exportin 1 | 0.0149415 |
| DUSP5 | dual specificity phosphatase 5 | 0.0148628 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0147789 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0147587 |
| IER2 | immediate early response 2 | 0.0147479 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0146662 |
| SET | SET nuclear proto-oncogene | 0.0146248 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0145755 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0144053 |
| RPL3 | ribosomal protein L3 | 0.0143874 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0142031 |
| DSTN | destrin (actin depolymerizing factor) | 0.0141001 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0140543 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0140182 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0139957 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0139162 |
| TCP1 | t-complex 1 | 0.0138558 |
| AHR | aryl hydrocarbon receptor | 0.0138389 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0137109 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0135772 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0135204 |
| FOSL2 | FOS-like antigen 2 | 0.0134514 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0132669 |
| METTL15 | methyltransferase like 15 | 0.0130308 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0128469 |
| RLIM | ring finger protein, LIM domain interacting | 0.0128173 |
| SMC1A | structural maintenance of chromosomes 1A | 0.012801 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0127556 |
| FAM3C | family with sequence similarity 3, member C | 0.0127503 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0124957 |
| PLAU | plasminogen activator, urokinase | 0.0124764 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0124749 |
| SFTPA2 | surfactant protein A2 | 0.0124381 |
| KIF4A | kinesin family member 4A | 0.0124102 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0122127 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | 0.012195 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.183768 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.140067 |
| IER3 | immediate early response 3 | -0.138732 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.118704 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.110716 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.106953 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.105967 |
| GLIS3 | GLIS family zinc finger 3 | -0.104611 |
| FRMD4A | FERM domain containing 4A | -0.0985529 |
| CADM1 | cell adhesion molecule 1 | -0.0977469 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0858801 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0846226 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0809449 |
| PDE10A | phosphodiesterase 10A | -0.0773626 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0735339 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0695927 |
| PGK1 | phosphoglycerate kinase 1 | -0.0656058 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0635493 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0634343 |
| CDH13 | cadherin 13 | -0.0613397 |
| HLA-B | major histocompatibility complex, class I, B | -0.0600723 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0581105 |
| RAI14 | retinoic acid induced 14 | -0.0574886 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0559028 |
| TMSB10 | thymosin beta 10 | -0.055637 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0534816 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0534573 |
| GNAS | GNAS complex locus | -0.0527384 |
| HMGA2 | high mobility group AT-hook 2 | -0.0525144 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0521663 |
| MYOF | myoferlin | -0.0505776 |
| MORF4L2 | mortality factor 4 like 2 | -0.0495919 |
| FMNL2 | formin-like 2 | -0.0481202 |
| EGFR | epidermal growth factor receptor | -0.0480003 |
| ADM | adrenomedullin | -0.0472973 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0470605 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0462013 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0461788 |
| TMEM132D | transmembrane protein 132D | -0.0455335 |
| DIAPH2 | diaphanous-related formin 2 | -0.0452062 |
| RRBP1 | ribosome binding protein 1 | -0.044955 |
| AFF3 | AF4/FMR2 family, member 3 | -0.043953 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0438876 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0435919 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0434368 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0429541 |
| RPS24 | ribosomal protein S24 | -0.042194 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0418722 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0410551 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0409804 |
| ANXA2 | annexin A2 | -0.040803 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0405341 |
| HLA-A | major histocompatibility complex, class I, A | -0.0405303 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0404886 |
| AHNAK | AHNAK nucleoprotein | -0.0401361 |
| RBM39 | RNA binding motif protein 39 | -0.0395079 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0388796 |
| ERBIN | erbb2 interacting protein | -0.0388319 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0387895 |
| NDRG1 | N-myc downstream regulated 1 | -0.0385132 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0383842 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0379905 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0379389 |
| DST | dystonin | -0.0379284 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0371236 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0371073 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0369397 |
| ACTG1 | actin gamma 1 | -0.0355865 |
| ZNF292 | zinc finger protein 292 | -0.034953 |
| SQSTM1 | sequestosome 1 | -0.034706 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0345441 |
| TMSB4X | thymosin beta 4, X-linked | -0.0343712 |
| CAVIN1 | caveolae associated protein 1 | -0.0341535 |
| NAV1 | neuron navigator 1 | -0.0340619 |
| CANX | calnexin | -0.0337879 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0336748 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0336684 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0335171 |
| LOX | lysyl oxidase | -0.0332399 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0330688 |
| RPS6 | ribosomal protein S6 | -0.0329044 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0325872 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0322521 |
| FUS | FUS RNA binding protein | -0.032208 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0321104 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0318459 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0317915 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0315736 |
| QKI | QKI, KH domain containing, RNA binding | -0.0312686 |
| CD44 | CD44 molecule (Indian blood group) | -0.030733 |
| FBXO11 | F-box protein 11 | -0.0306132 |
| SMYD3 | SET and MYND domain containing 3 | -0.0305845 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0303226 |
| FTL | ferritin, light polypeptide | -0.0299792 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0293289 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0293042 |
| CLMP | CXADR-like membrane protein | -0.028824 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0282399 |
| MED13 | mediator complex subunit 13 | -0.0282283 |
| MMP12 | matrix metallopeptidase 12 | -0.0281412 |
