| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRELID2 | PRELI domain containing 2 | 0.0438995 |
| HMGA2 | high mobility group AT-hook 2 | 0.043425 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0431325 |
| KYNU | kynureninase | 0.0430404 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0425859 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0415117 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0400411 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0379544 |
| PRKCA | protein kinase C, alpha | 0.0376276 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0373564 |
| FN1 | fibronectin 1 | 0.0343007 |
| AHNAK | AHNAK nucleoprotein | 0.0332615 |
| GLIS3 | GLIS family zinc finger 3 | 0.0331876 |
| VEGFA | vascular endothelial growth factor A | 0.0330812 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0330461 |
| GOLGB1 | golgin B1 | 0.0325749 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0322522 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0310205 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0306013 |
| DIAPH3 | diaphanous-related formin 3 | 0.0305886 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0303113 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0300416 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0299245 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0299134 |
| SMYD3 | SET and MYND domain containing 3 | 0.0292005 |
| TANK | TRAF family member-associated NFKB activator | 0.0288996 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0287485 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0281409 |
| CENPF | centromere protein F, 350/400kDa | 0.0280775 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.027263 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0268713 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0267894 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0265172 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0264773 |
| CTSB | cathepsin B | 0.026229 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0261071 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0259462 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0259089 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0254157 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0251566 |
| COL5A1 | collagen, type V, alpha 1 | 0.0251506 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0245191 |
| SFTPA2 | surfactant protein A2 | 0.0244965 |
| GSE1 | Gse1 coiled-coil protein | 0.0242327 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0234649 |
| PCNX1 | pecanex 1 | 0.0231778 |
| EGFR | epidermal growth factor receptor | 0.0229431 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0229185 |
| IL6 | interleukin 6 | 0.0228154 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.022777 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0227532 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0227133 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0226078 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.0225369 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0223831 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0223765 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0221643 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0220625 |
| CDK13 | cyclin-dependent kinase 13 | 0.0220024 |
| CDK19 | cyclin-dependent kinase 19 | 0.0216566 |
| UBAP2 | ubiquitin associated protein 2 | 0.021635 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0215218 |
| SCFD2 | sec1 family domain containing 2 | 0.0215205 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0214369 |
| GPR173 | G protein-coupled receptor 173 | 0.0210122 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.0209808 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0209233 |
| NRXN3 | neurexin 3 | 0.0208718 |
| SSH2 | slingshot protein phosphatase 2 | 0.0206861 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0206515 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0205737 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0205089 |
| ZNF133 | zinc finger protein 133 | 0.0204361 |
| MYO9B | myosin IXB | 0.0202901 |
| RAD51B | RAD51 paralog B | 0.0202593 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0200699 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.020007 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0199249 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.019922 |
| SERINC1 | serine incorporator 1 | 0.0198909 |
| TMF1 | TATA element modulatory factor 1 | 0.019874 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 | 0.0197399 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0195855 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0195368 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0194704 |
| GLG1 | golgi glycoprotein 1 | 0.0192111 |
| CUL4A | cullin 4A | 0.0191615 |
| AAK1 | AP2 associated kinase 1 | 0.0191327 |
| POTEF | POTE ankyrin domain family, member F | 0.0190827 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0188197 |
| ZNF841 | zinc finger protein 841 | 0.0187497 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0187439 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0186192 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0184891 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0184558 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0184425 |
| TRIM44 | tripartite motif containing 44 | 0.0184377 |
| BPTF | bromodomain PHD finger transcription factor | 0.0184064 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.018388 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0183759 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.232714 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.107772 |
| MT2A | metallothionein 2A | -0.0844656 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0761274 |
| B2M | beta-2-microglobulin | -0.0704496 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0681141 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0597646 |
| TMSB10 | thymosin beta 10 | -0.0558981 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0547277 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0547146 |
| RBM39 | RNA binding motif protein 39 | -0.0531179 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0519215 |
| NDRG1 | N-myc downstream regulated 1 | -0.0518395 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0506068 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0493789 |
| VIM | vimentin | -0.0493658 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0470309 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0469954 |
| COL1A2 | collagen, type I, alpha 2 | -0.0468273 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0462873 |
| ZNF292 | zinc finger protein 292 | -0.0458799 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0451665 |
| ENO1 | enolase 1, (alpha) | -0.0444956 |
| UBC | ubiquitin C | -0.0421336 |
| ANXA2 | annexin A2 | -0.0415234 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0411852 |
| ADM | adrenomedullin | -0.0409003 |
| TFG | TRK-fused gene | -0.0407082 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0405592 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0401505 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0398361 |
| PRRC2C | proline-rich coiled-coil 2C | -0.039526 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0387894 |
| FTL | ferritin, light polypeptide | -0.0378523 |
| ZNF395 | zinc finger protein 395 | -0.0367897 |
| RPL11 | ribosomal protein L11 | -0.0367616 |
| HLA-B | major histocompatibility complex, class I, B | -0.0365863 |
| QKI | QKI, KH domain containing, RNA binding | -0.0364972 |
| FAM13A | family with sequence similarity 13, member A | -0.0363169 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.035558 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0355268 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0352748 |
| INHBA | inhibin, beta A | -0.0346685 |
| COL1A1 | collagen, type I, alpha 1 | -0.0346325 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0345619 |
| PKM | pyruvate kinase, muscle | -0.0345308 |
| ARF4 | ADP-ribosylation factor 4 | -0.033609 |
| STC1 | stanniocalcin 1 | -0.0334773 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0332351 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0326363 |
| RLF | rearranged L-myc fusion | -0.0317667 |
| WAC | WW domain containing adaptor with coiled-coil | -0.030946 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0309186 |
| RTN4 | reticulon 4 | -0.0308868 |
| H3-3B | H3.3 histone B | -0.0304661 |
| S100A6 | S100 calcium binding protein A6 | -0.0298654 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0297354 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.029372 |
| RPS6 | ribosomal protein S6 | -0.0292829 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0290992 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0286494 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0284817 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0279758 |
| INSIG2 | insulin induced gene 2 | -0.0279604 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0279092 |
| RPL19 | ribosomal protein L19 | -0.0277589 |
| LOX | lysyl oxidase | -0.0276857 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0275874 |
| NOP58 | NOP58 ribonucleoprotein | -0.0273758 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0271255 |
| EGR1 | early growth response 1 | -0.0270604 |
| S100A10 | S100 calcium binding protein A10 | -0.0270057 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0268355 |
| TPM1 | tropomyosin 1 (alpha) | -0.0268268 |
| CADM1 | cell adhesion molecule 1 | -0.0266872 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0266426 |
| EHD2 | EH-domain containing 2 | -0.0264937 |
| HIP1 | huntingtin interacting protein 1 | -0.0263114 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0260556 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0259841 |
| EMP1 | epithelial membrane protein 1 | -0.025948 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0259371 |
| TPI1 | triosephosphate isomerase 1 | -0.0257394 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0256971 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0255505 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0255306 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0255051 |
| S100A9 | S100 calcium binding protein A9 | -0.0253907 |
| HLA-C | major histocompatibility complex, class I, C | -0.0252022 |
| CD99 | CD99 molecule | -0.0251323 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | -0.0248667 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.024628 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0245118 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0244969 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0243549 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0240211 |
| NABP1 | nucleic acid binding protein 1 | -0.0239931 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0238165 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0237182 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0236709 |
