| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0800149 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0487535 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0465339 |
| VMP1 | vacuole membrane protein 1 | 0.045999 |
| BRD2 | bromodomain containing 2 | 0.0450182 |
| XPO1 | exportin 1 | 0.0432222 |
| YAP1 | Yes-associated protein 1 | 0.041353 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0411941 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0391942 |
| ANXA11 | annexin A11 | 0.0386636 |
| POTEF | POTE ankyrin domain family, member F | 0.0384004 |
| CCNL1 | cyclin L1 | 0.0366417 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.036517 |
| GPHN | gephyrin | 0.0357982 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0355144 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0340936 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0332707 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0327682 |
| FAT1 | FAT atypical cadherin 1 | 0.032649 |
| BCL2L1 | BCL2-like 1 | 0.0326048 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0322518 |
| VEGFA | vascular endothelial growth factor A | 0.0320371 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0309543 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0307968 |
| FAM3C | family with sequence similarity 3, member C | 0.0307304 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0305541 |
| SMYD3 | SET and MYND domain containing 3 | 0.030238 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0292121 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0289899 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0286398 |
| RTN4 | reticulon 4 | 0.028352 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0283056 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0280002 |
| PLEC | plectin | 0.0276199 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0275485 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0271964 |
| PRELID2 | PRELI domain containing 2 | 0.0269213 |
| CLDN4 | claudin 4 | 0.0263828 |
| ZNF148 | zinc finger protein 148 | 0.0262271 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0261617 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0261481 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0260038 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0255812 |
| EXOC6B | exocyst complex component 6B | 0.025394 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0251957 |
| ZNF638 | zinc finger protein 638 | 0.0248905 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0248635 |
| VCL | vinculin | 0.024129 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.023516 |
| FHL2 | four and a half LIM domains 2 | 0.0232885 |
| TGFA | transforming growth factor, alpha | 0.0230279 |
| ARRDC3 | arrestin domain containing 3 | 0.0229587 |
| ITGAV | integrin, alpha V | 0.0227681 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0216578 |
| DST | dystonin | 0.0212656 |
| MYO1E | myosin IE | 0.0207671 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0205957 |
| MEF2A | myocyte enhancer factor 2A | 0.020407 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0202215 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0201291 |
| SMAD3 | SMAD family member 3 | 0.0200267 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0197738 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0197527 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0196015 |
| PTEN | phosphatase and tensin homolog | 0.0192514 |
| IL18 | interleukin 18 | 0.0190684 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0190628 |
| STK24 | serine/threonine kinase 24 | 0.0189799 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0189048 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.0186537 |
| NHSL1 | NHS-like 1 | 0.0186201 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0183481 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0183179 |
| FOSL2 | FOS-like antigen 2 | 0.0181478 |
| CDCP1 | CUB domain containing protein 1 | 0.0181364 |
| TXNRD1 | thioredoxin reductase 1 | 0.0180454 |
| CAPN5 | calpain 5 | 0.0178856 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0178127 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0177298 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0175756 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0174837 |
| KIAA0040 | KIAA0040 | 0.0174391 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0173304 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0173087 |
| KIAA1217 | KIAA1217 | 0.0172664 |
| KRT80 | keratin 80, type II | 0.0172229 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0171247 |
| EFNA5 | ephrin-A5 | 0.0169999 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0169626 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0169329 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0168974 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0168484 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0167632 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0167281 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0167173 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0166732 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0166114 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0166006 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0165776 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0164094 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.29608 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0964011 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0844291 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0800197 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0789958 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.077775 |
| TMEM123 | transmembrane protein 123 | -0.0775648 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0757776 |
| TMSB10 | thymosin beta 10 | -0.0725613 |
| GNAS | GNAS complex locus | -0.0677539 |
| FRMD5 | FERM domain containing 5 | -0.0663175 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0638209 |
| KRT18 | keratin 18, type I | -0.0634279 |
| FTL | ferritin, light polypeptide | -0.0630653 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0612525 |
| EHBP1 | EH domain binding protein 1 | -0.058058 |
| H1-0 | H1.0 linker histone | -0.0528834 |
| NFIA | nuclear factor I/A | -0.0525256 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0521444 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0518209 |
| PGK1 | phosphoglycerate kinase 1 | -0.0516228 |
| TOP1 | topoisomerase (DNA) I | -0.0481359 |
| S100A6 | S100 calcium binding protein A6 | -0.047598 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0469175 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0464401 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0461769 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.045634 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0454619 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0453532 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0439265 |
| AHNAK | AHNAK nucleoprotein | -0.0436674 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0436629 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0435874 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0418848 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0414425 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0411298 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0409194 |
| ANXA2 | annexin A2 | -0.0407466 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0403037 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0402646 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0398151 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0395875 |
| S100A10 | S100 calcium binding protein A10 | -0.0395438 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0395314 |
| CD2AP | CD2-associated protein | -0.0392839 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0389418 |
| RPL19 | ribosomal protein L19 | -0.0381393 |
| IER3 | immediate early response 3 | -0.0377356 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0375602 |
| SQSTM1 | sequestosome 1 | -0.0368828 |
| TPX2 | TPX2, microtubule-associated | -0.0364131 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0362527 |
| RPS24 | ribosomal protein S24 | -0.035622 |
| BBX | bobby sox homolog (Drosophila) | -0.0352771 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.0351564 |
| CENPF | centromere protein F, 350/400kDa | -0.0351517 |
| RBM39 | RNA binding motif protein 39 | -0.0350519 |
| PERP | PERP, TP53 apoptosis effector | -0.0347883 |
| USP3 | ubiquitin specific peptidase 3 | -0.0347809 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0346173 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0338626 |
| CCND1 | cyclin D1 | -0.0336631 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0335496 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0335437 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0334894 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0329899 |
| ECT2 | epithelial cell transforming 2 | -0.0327565 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0327036 |
| FUS | FUS RNA binding protein | -0.0326733 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0321542 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0321069 |
| TFRC | transferrin receptor | -0.0320457 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0318167 |
| UBC | ubiquitin C | -0.031669 |
| NDRG1 | N-myc downstream regulated 1 | -0.0316145 |
| NOP58 | NOP58 ribonucleoprotein | -0.031305 |
| MSI2 | musashi RNA-binding protein 2 | -0.0312324 |
| RPL8 | ribosomal protein L8 | -0.0310111 |
| RPL32 | ribosomal protein L32 | -0.0309443 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0304737 |
| RPL18 | ribosomal protein L18 | -0.03025 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0301403 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | -0.0300468 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0299834 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0299536 |
| EZR | ezrin | -0.029702 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0295357 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.029128 |
| RPL35A | ribosomal protein L35a | -0.02912 |
| LMNA | lamin A/C | -0.0289055 |
| RPS5 | ribosomal protein S5 | -0.0286996 |
| RPS13 | ribosomal protein S13 | -0.0283232 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0282012 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0281929 |
| RPS21 | ribosomal protein S21 | -0.0280301 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.027847 |
| RPL37A | ribosomal protein L37a | -0.0275004 |
| FNBP1L | formin binding protein 1-like | -0.0274729 |
| CDK13 | cyclin-dependent kinase 13 | -0.0274582 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0272864 |
