| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.15473 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.106047 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0991817 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0983326 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0978246 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0879685 |
| HLA-B | major histocompatibility complex, class I, B | 0.0737365 |
| VEGFA | vascular endothelial growth factor A | 0.0717394 |
| HMGA2 | high mobility group AT-hook 2 | 0.0664844 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0648716 |
| DST | dystonin | 0.062861 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0625341 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0589054 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0538867 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0529326 |
| CDH13 | cadherin 13 | 0.0490538 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0477306 |
| MMP12 | matrix metallopeptidase 12 | 0.0464675 |
| NCKAP5 | NCK-associated protein 5 | 0.0458318 |
| NAV2 | neuron navigator 2 | 0.0447137 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0440092 |
| INHBA | inhibin, beta A | 0.0415988 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0415888 |
| GOLGA4 | golgin A4 | 0.0412679 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0408479 |
| STC2 | stanniocalcin 2 | 0.040552 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0382905 |
| NPTX1 | neuronal pentraxin I | 0.0370151 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0358468 |
| B2M | beta-2-microglobulin | 0.035734 |
| NGLY1 | N-glycanase 1 | 0.0353058 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0342349 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0333443 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0329282 |
| PRELID2 | PRELI domain containing 2 | 0.0320304 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0314526 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0293053 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0288562 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0286725 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0285852 |
| DNER | delta/notch-like EGF repeat containing | 0.0276927 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0274122 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0273407 |
| ZNF292 | zinc finger protein 292 | 0.0272914 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | 0.0271926 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0271894 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0265815 |
| TNS1 | tensin 1 | 0.0265731 |
| RPS12 | ribosomal protein S12 | 0.0260922 |
| FMNL2 | formin-like 2 | 0.0251627 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.025061 |
| TMF1 | TATA element modulatory factor 1 | 0.0245903 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0242664 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0241826 |
| ATXN1 | ataxin 1 | 0.0237787 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0237487 |
| SP100 | SP100 nuclear antigen | 0.0235572 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0234491 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0232849 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0231862 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0231064 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0229893 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0227801 |
| MSN | moesin | 0.0224506 |
| FNIP1 | folliculin interacting protein 1 | 0.0223898 |
| HLA-A | major histocompatibility complex, class I, A | 0.022345 |
| TMEM165 | transmembrane protein 165 | 0.0223285 |
| CUX1 | cut-like homeobox 1 | 0.022175 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0221386 |
| RNF150 | ring finger protein 150 | 0.0221293 |
| ZNF451 | zinc finger protein 451 | 0.0217348 |
| VIM | vimentin | 0.0216801 |
| YEATS2 | YEATS domain containing 2 | 0.0215789 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0215079 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0213108 |
| STC1 | stanniocalcin 1 | 0.0211898 |
| RSF1 | remodeling and spacing factor 1 | 0.0208642 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0207156 |
| ARHGAP10 | Rho GTPase activating protein 10 | 0.020631 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0202178 |
| TUT7 | terminal uridylyl transferase 7 | 0.0200937 |
| RAD51B | RAD51 paralog B | 0.0200638 |
| ITGA11 | integrin, alpha 11 | 0.0199365 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0195073 |
| GPATCH2L | G patch domain containing 2-like | 0.0191863 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0191026 |
| TMSB4X | thymosin beta 4, X-linked | 0.0190752 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0187642 |
| ATP13A3 | ATPase type 13A3 | 0.0186761 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0186661 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0185623 |
| SEPTIN9 | septin 9 | 0.0182648 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0181611 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0181046 |
| PCBP3 | poly(rC) binding protein 3 | 0.0180643 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0180511 |
| BNC2 | basonuclin 2 | 0.0179044 |
| INSIG1 | insulin induced gene 1 | 0.0176946 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0176255 |
| CANX | calnexin | 0.0174464 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.343764 |
| FN1 | fibronectin 1 | -0.260251 |
| COL6A3 | collagen, type VI, alpha 3 | -0.16584 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.158012 |
| CD44 | CD44 molecule (Indian blood group) | -0.122628 |
| EMP1 | epithelial membrane protein 1 | -0.111924 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0852985 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0760189 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0705684 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0621959 |
| ASPH | aspartate beta-hydroxylase | -0.061616 |
| VCL | vinculin | -0.0609226 |
| SMAD3 | SMAD family member 3 | -0.0594846 |
| ANXA2 | annexin A2 | -0.0591007 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0567289 |
| EGFR | epidermal growth factor receptor | -0.0560585 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0541639 |
| CALD1 | caldesmon 1 | -0.0536711 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0532695 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0521892 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0507532 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.049805 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0488887 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.043956 |
| RAI14 | retinoic acid induced 14 | -0.0432748 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0428917 |
| FTL | ferritin, light polypeptide | -0.0425752 |
| HDLBP | high density lipoprotein binding protein | -0.0401884 |
| COL1A2 | collagen, type I, alpha 2 | -0.0401365 |
| FRMD4A | FERM domain containing 4A | -0.0393509 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0386197 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.037751 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0371439 |
| NDRG1 | N-myc downstream regulated 1 | -0.0366407 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.035082 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0349496 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0344416 |
| CCDC102B | coiled-coil domain containing 102B | -0.0342975 |
| CAVIN1 | caveolae associated protein 1 | -0.0321527 |
| TMSB10 | thymosin beta 10 | -0.0319076 |
| COL4A2 | collagen, type IV, alpha 2 | -0.031814 |
| LDHA | lactate dehydrogenase A | -0.0315721 |
| DIAPH2 | diaphanous-related formin 2 | -0.0302692 |
| SEPTIN11 | septin 11 | -0.0292467 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0291528 |
| CLTC | clathrin, heavy chain (Hc) | -0.0290532 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0289534 |
| AHNAK | AHNAK nucleoprotein | -0.0286601 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0285035 |
| LOX | lysyl oxidase | -0.0284522 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.0275777 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0268605 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0268404 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0265836 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0263765 |
| PALLD | palladin, cytoskeletal associated protein | -0.0255773 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0251435 |
| RRBP1 | ribosome binding protein 1 | -0.0248616 |
| MYO10 | myosin X | -0.0248512 |
| COL4A1 | collagen, type IV, alpha 1 | -0.0246554 |
| KLF6 | Kruppel-like factor 6 | -0.0242403 |
| PGK1 | phosphoglycerate kinase 1 | -0.0242145 |
| PDE8A | phosphodiesterase 8A | -0.0239017 |
| THBS2 | thrombospondin 2 | -0.0237599 |
| RPLP1 | ribosomal protein, large, P1 | -0.0236845 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0235719 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0233388 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0231673 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0230837 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0229985 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0228256 |
| PKM | pyruvate kinase, muscle | -0.022757 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0227284 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0226841 |
| KLF10 | Kruppel-like factor 10 | -0.0226181 |
| SEC24D | SEC24 family member D | -0.0221076 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0216427 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.021436 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0213984 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0213747 |
| EGR1 | early growth response 1 | -0.0212654 |
| LOXL2 | lysyl oxidase-like 2 | -0.0212019 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0210348 |
| CPA6 | carboxypeptidase A6 | -0.0210051 |
| JAG1 | jagged 1 | -0.020855 |
| SRPK2 | SRSF protein kinase 2 | -0.0208263 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0207139 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0206872 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0204915 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0203181 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0201209 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0200651 |
| GLG1 | golgi glycoprotein 1 | -0.0199576 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0199071 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0197785 |
| RHOQ | ras homolog family member Q | -0.0195838 |
| RAB31 | RAB31, member RAS oncogene family | -0.0195814 |
| ARHGAP31 | Rho GTPase activating protein 31 | -0.0193774 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0192812 |
| FAT1 | FAT atypical cadherin 1 | -0.0192521 |
