| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Volasertib perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Volasertib_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.132187 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.116453 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0632113 |
| HDAC9 | histone deacetylase 9 | 0.0579402 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0576463 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0562951 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0557082 |
| NAV2 | neuron navigator 2 | 0.0509235 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0470377 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0464493 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0430496 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0430492 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0399664 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0396421 |
| FNIP1 | folliculin interacting protein 1 | 0.0370558 |
| DST | dystonin | 0.0364005 |
| RUNX1 | runt-related transcription factor 1 | 0.0363063 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0316844 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0302647 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0293084 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0290815 |
| PRELID2 | PRELI domain containing 2 | 0.0270119 |
| TPM3 | tropomyosin 3 | 0.0268479 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0259036 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0254878 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0251107 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0246543 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0245493 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0245469 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0243017 |
| APP | amyloid beta (A4) precursor protein | 0.0237405 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0236163 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0235169 |
| TMSB4X | thymosin beta 4, X-linked | 0.0234007 |
| CD109 | CD109 molecule | 0.0231489 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0230529 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0226605 |
| EGFR | epidermal growth factor receptor | 0.0223248 |
| SQSTM1 | sequestosome 1 | 0.0221648 |
| SBF2 | SET binding factor 2 | 0.0218135 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0218099 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0216952 |
| AUTS2 | autism susceptibility candidate 2 | 0.0216903 |
| RND3 | Rho family GTPase 3 | 0.0215672 |
| HELZ | helicase with zinc finger | 0.0212901 |
| ATP13A3 | ATPase type 13A3 | 0.0209966 |
| SUCO | SUN domain containing ossification factor | 0.0206159 |
| PTK2 | protein tyrosine kinase 2 | 0.0199959 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0199775 |
| USP34 | ubiquitin specific peptidase 34 | 0.0198449 |
| OGA | O-GlcNAcase | 0.0196535 |
| ZNF292 | zinc finger protein 292 | 0.0192798 |
| CDH13 | cadherin 13 | 0.0191233 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0188232 |
| MYOF | myoferlin | 0.0187784 |
| TAOK1 | TAO kinase 1 | 0.0184057 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0183139 |
| ANO6 | anoctamin 6 | 0.018281 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0182222 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0181956 |
| ERBIN | erbb2 interacting protein | 0.0177161 |
| COPA | coatomer protein complex, subunit alpha | 0.0175748 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0174394 |
| ARFGEF3 | ARFGEF family member 3 | 0.017267 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0170916 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0169352 |
| JMJD1C | jumonji domain containing 1C | 0.0166596 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0166377 |
| MSN | moesin | 0.0165632 |
| EFNA5 | ephrin-A5 | 0.0165552 |
| CREB5 | cAMP responsive element binding protein 5 | 0.016442 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0164054 |
| MB21D2 | Mab-21 domain containing 2 | 0.0163366 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0163157 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0163153 |
| SMYD3 | SET and MYND domain containing 3 | 0.0160607 |
| NCKAP1 | NCK-associated protein 1 | 0.015916 |
| GPC6 | glypican 6 | 0.0157991 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0157046 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0156046 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0155317 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0154378 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0152488 |
| FLNB | filamin B, beta | 0.015234 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0151727 |
| DENND1A | DENN/MADD domain containing 1A | 0.015146 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0151241 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0151233 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0150557 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0149966 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0149847 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.01482 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0148124 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0147633 |
| FMNL2 | formin-like 2 | 0.0147399 |
| ATXN1 | ataxin 1 | 0.0147282 |
| TLE4 | transducin-like enhancer of split 4 | 0.0147037 |
| ANK2 | ankyrin 2, neuronal | 0.0146875 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0146773 |
| FSTL1 | follistatin-like 1 | 0.0146755 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.270962 |
| TMSB10 | thymosin beta 10 | -0.199141 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.176293 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.168221 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109531 |
| MT2A | metallothionein 2A | -0.0962518 |
| PLAT | plasminogen activator, tissue | -0.0895066 |
| PODXL | podocalyxin-like | -0.0841445 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0809445 |
| FN1 | fibronectin 1 | -0.0761485 |
| HLA-B | major histocompatibility complex, class I, B | -0.0746564 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0693343 |
| PTMA | prothymosin, alpha | -0.0693083 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0674258 |
| S100A6 | S100 calcium binding protein A6 | -0.0642267 |
| S100A10 | S100 calcium binding protein A10 | -0.0609991 |
| LOX | lysyl oxidase | -0.055609 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0545102 |
| PRSS23 | protease, serine, 23 | -0.0542454 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0520357 |
| LMNA | lamin A/C | -0.0505676 |
| COL5A1 | collagen, type V, alpha 1 | -0.0500786 |
| SUCNR1 | succinate receptor 1 | -0.0484418 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0476947 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0463704 |
| CSTB | cystatin B (stefin B) | -0.0462889 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0460686 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0440968 |
| NDRG1 | N-myc downstream regulated 1 | -0.0425449 |
| HLA-C | major histocompatibility complex, class I, C | -0.0395297 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0388132 |
| TAGLN2 | transgelin 2 | -0.0386285 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0382433 |
| MX2 | MX dynamin-like GTPase 2 | -0.0381867 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0360691 |
| CAVIN1 | caveolae associated protein 1 | -0.0347606 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0338936 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0336004 |
| COL1A2 | collagen, type I, alpha 2 | -0.0331505 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0330766 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0326595 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0317317 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0306837 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0302681 |
| RPL35A | ribosomal protein L35a | -0.0295139 |
| MYADM | myeloid-associated differentiation marker | -0.0285193 |
| FTL | ferritin, light polypeptide | -0.0284911 |
| LOXL2 | lysyl oxidase-like 2 | -0.0265827 |
| S100A11 | S100 calcium binding protein A11 | -0.0264422 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0251539 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0250496 |
| POTEF | POTE ankyrin domain family, member F | -0.0248786 |
| S100A4 | S100 calcium binding protein A4 | -0.0246697 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0239146 |
| CD99 | CD99 molecule | -0.0236413 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.023498 |
| HLA-A | major histocompatibility complex, class I, A | -0.0234324 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0232257 |
| TPM1 | tropomyosin 1 (alpha) | -0.0230193 |
| COL5A2 | collagen, type V, alpha 2 | -0.0228116 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0226863 |
| LRRC17 | leucine rich repeat containing 17 | -0.0215275 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0212998 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.020803 |
| PKM | pyruvate kinase, muscle | -0.0207613 |
| RIGI | RNA sensor RIG-I | -0.0206332 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0205326 |
| FBN1 | fibrillin 1 | -0.0202132 |
| KRT81 | keratin 81, type II | -0.0200056 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0199004 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0197996 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0197604 |
| GNAS | GNAS complex locus | -0.0195775 |
| RPLP1 | ribosomal protein, large, P1 | -0.0193798 |
| NAV1 | neuron navigator 1 | -0.0189513 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0188913 |
| S100A9 | S100 calcium binding protein A9 | -0.0187962 |
| IL7R | interleukin 7 receptor | -0.0187721 |
| UBC | ubiquitin C | -0.0185504 |
| CALR | calreticulin | -0.0185058 |
| COL1A1 | collagen, type I, alpha 1 | -0.0183376 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0182956 |
| MAP1B | microtubule-associated protein 1B | -0.0182767 |
| CUX1 | cut-like homeobox 1 | -0.0179679 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0178531 |
| RPL28 | ribosomal protein L28 | -0.0177773 |
| CTSB | cathepsin B | -0.0176516 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0176006 |
| PXDN | peroxidasin | -0.0174943 |
| B2M | beta-2-microglobulin | -0.0168317 |
| SEC61G | Sec61 gamma subunit | -0.0167979 |
| H3-3B | H3.3 histone B | -0.0167892 |
| TPI1 | triosephosphate isomerase 1 | -0.0167387 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0166941 |
| MT1X | metallothionein 1X | -0.0166678 |
| RPS8 | ribosomal protein S8 | -0.0166501 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0166408 |
| TNS3 | tensin 3 | -0.0166176 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0165546 |
| PFN1 | profilin 1 | -0.0165404 |
