| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Volasertib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Volasertib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.131068 |
| FMN1 | formin 1 | 0.123505 |
| TLE4 | transducin-like enhancer of split 4 | 0.101507 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0809734 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0670205 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0640817 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0638284 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0629441 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0611547 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0589228 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0573283 |
| B2M | beta-2-microglobulin | 0.0518027 |
| SMYD3 | SET and MYND domain containing 3 | 0.0482749 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0434894 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.040344 |
| PLAT | plasminogen activator, tissue | 0.037143 |
| NRG1 | neuregulin 1 | 0.0369247 |
| BPTF | bromodomain PHD finger transcription factor | 0.0365855 |
| GLCCI1 | glucocorticoid induced 1 | 0.0362135 |
| FAM107B | family with sequence similarity 107, member B | 0.0348291 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.033479 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0334269 |
| DST | dystonin | 0.0326506 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0319391 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0319204 |
| CENPF | centromere protein F, 350/400kDa | 0.0317683 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0317142 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0313416 |
| SYT1 | synaptotagmin I | 0.0303781 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0301803 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0301427 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0296343 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0295971 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0288764 |
| GPATCH8 | G patch domain containing 8 | 0.0288294 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0286937 |
| INTS6 | integrator complex subunit 6 | 0.0286925 |
| RPS27A | ribosomal protein S27a | 0.02836 |
| MYO6 | myosin VI | 0.0281617 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0281413 |
| AFF4 | AF4/FMR2 family, member 4 | 0.028067 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0279851 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0279181 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0278716 |
| ANKRD12 | ankyrin repeat domain 12 | 0.027771 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0273557 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0272622 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0272559 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0271748 |
| PDE10A | phosphodiesterase 10A | 0.0270058 |
| IER3 | immediate early response 3 | 0.0269586 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0268183 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0265801 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0264586 |
| ACTN1 | actinin, alpha 1 | 0.0263733 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0263673 |
| SIK2 | salt-inducible kinase 2 | 0.0260237 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0259935 |
| HAND2 | heart and neural crest derivatives expressed 2 | 0.0257545 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0253902 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0247794 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0247752 |
| MED13 | mediator complex subunit 13 | 0.0245944 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0245375 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0239816 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0239619 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0239172 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0238289 |
| AMOTL1 | angiomotin like 1 | 0.0237801 |
| TPM1 | tropomyosin 1 (alpha) | 0.0237395 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0236983 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0236727 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0235498 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.023455 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0228171 |
| DNM3 | dynamin 3 | 0.0225079 |
| DUSP16 | dual specificity phosphatase 16 | 0.0223953 |
| FRMD4A | FERM domain containing 4A | 0.022342 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0222576 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0221934 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0221875 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0221762 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.022117 |
| ZNF804A | zinc finger protein 804A | 0.0220535 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0218019 |
| TCF12 | transcription factor 12 | 0.0217979 |
| LMNA | lamin A/C | 0.0215913 |
| RIGI | RNA sensor RIG-I | 0.0215651 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0213434 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0211524 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0211173 |
| PCBP3 | poly(rC) binding protein 3 | 0.0210534 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0210073 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0209175 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0208518 |
| PLPP1 | phospholipid phosphatase 1 | 0.0207966 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.020779 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0206453 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0203151 |
| NEO1 | neogenin 1 | 0.0202525 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.571145 |
| IGF2 | insulin-like growth factor 2 | -0.172714 |
| PTMA | prothymosin, alpha | -0.0559173 |
| VIM | vimentin | -0.0426624 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0401258 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0395217 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.035523 |
| CANX | calnexin | -0.034442 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0337231 |
| NDRG1 | N-myc downstream regulated 1 | -0.033273 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0331294 |
| WDR45B | WD repeat domain 45B | -0.032102 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0318328 |
| LPIN1 | lipin 1 | -0.0308231 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0298877 |
| RPS6 | ribosomal protein S6 | -0.0298413 |
| SCG2 | secretogranin II | -0.0282818 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.026782 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0255084 |
| LDHB | lactate dehydrogenase B | -0.0253237 |
| USP3 | ubiquitin specific peptidase 3 | -0.0248803 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0247786 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0247507 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0245694 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0238714 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0236253 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.023573 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0233385 |
| RPLP0 | ribosomal protein, large, P0 | -0.023302 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.022989 |
| RPS24 | ribosomal protein S24 | -0.0229257 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0227015 |
| RO60 | Ro60, Y RNA binding protein | -0.0225525 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0224238 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0222943 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0221454 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0220074 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0213543 |
| SETD5 | SET domain containing 5 | -0.0211782 |
| POTEF | POTE ankyrin domain family, member F | -0.0209098 |
| USP34 | ubiquitin specific peptidase 34 | -0.0209012 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0208806 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0207434 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0206435 |
| RNF150 | ring finger protein 150 | -0.0206382 |
| TPI1 | triosephosphate isomerase 1 | -0.0200985 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0200769 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0197403 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.019492 |
| DSTN | destrin (actin depolymerizing factor) | -0.0193281 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0189109 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0188579 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0187243 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0187103 |
| RPL35A | ribosomal protein L35a | -0.0187004 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0185884 |
| COPA | coatomer protein complex, subunit alpha | -0.0185688 |
| PUM2 | pumilio RNA-binding family member 2 | -0.018474 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0183439 |
| HMGA1 | high mobility group AT-hook 1 | -0.0178869 |
| CDK19 | cyclin-dependent kinase 19 | -0.0176727 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0176168 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0173772 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0172063 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0171327 |
| ANXA2 | annexin A2 | -0.0171157 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0169753 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | -0.016971 |
| CCNY | cyclin Y | -0.0169183 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0169016 |
| THOC1 | THO complex 1 | -0.0168056 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0166516 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.016592 |
| PLCB4 | phospholipase C, beta 4 | -0.0160282 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0159585 |
| SEPTIN2 | septin 2 | -0.0159303 |
| UBE3D | ubiquitin protein ligase E3D | -0.0159216 |
| TENM3 | teneurin transmembrane protein 3 | -0.0159134 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0158181 |
| ZFR | zinc finger RNA binding protein | -0.0156385 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | -0.0154964 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | -0.0154053 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0154027 |
| CUX1 | cut-like homeobox 1 | -0.0153541 |
| FBL | fibrillarin | -0.0153448 |
| PRTG | protogenin | -0.0151268 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0150464 |
| FNBP4 | formin binding protein 4 | -0.0150412 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0150393 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0150368 |
| RBM26 | RNA binding motif protein 26 | -0.0149265 |
| AOPEP | aminopeptidase O (putative) | -0.0148948 |
| PFN1 | profilin 1 | -0.0148905 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0148755 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0148252 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0148097 |
| CEP95 | centrosomal protein 95kDa | -0.0147621 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.0146668 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | -0.0146146 |
| RPS4X | ribosomal protein S4, X-linked | -0.0146112 |
