| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Volasertib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Volasertib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.25128 |
| EXT1 | exostosin glycosyltransferase 1 | 0.080978 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0750488 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0659483 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0654754 |
| INTS6 | integrator complex subunit 6 | 0.0641612 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0625406 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0589416 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0584551 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.05423 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0514857 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0497689 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0493981 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0489434 |
| FNIP1 | folliculin interacting protein 1 | 0.0473586 |
| PHF3 | PHD finger protein 3 | 0.0464386 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0433293 |
| SMAD3 | SMAD family member 3 | 0.0427896 |
| HKDC1 | hexokinase domain containing 1 | 0.0412006 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0394415 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0380593 |
| EFNB2 | ephrin-B2 | 0.0378824 |
| PDZD8 | PDZ domain containing 8 | 0.036732 |
| TJP1 | tight junction protein 1 | 0.0356737 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0354607 |
| SPAG9 | sperm associated antigen 9 | 0.0337336 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0337255 |
| MYO5B | myosin VB | 0.0311439 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0310337 |
| DST | dystonin | 0.0308742 |
| DUSP10 | dual specificity phosphatase 10 | 0.0308643 |
| SEC24D | SEC24 family member D | 0.0307462 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0306177 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0298401 |
| ZNF292 | zinc finger protein 292 | 0.0289703 |
| FNIP2 | folliculin interacting protein 2 | 0.0282111 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0277808 |
| AFF4 | AF4/FMR2 family, member 4 | 0.027484 |
| MYO1E | myosin IE | 0.0269569 |
| ASPH | aspartate beta-hydroxylase | 0.0269432 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.0257877 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0255579 |
| KYNU | kynureninase | 0.0254876 |
| PLSCR2 | phospholipid scramblase 2 | 0.0251492 |
| TMEM65 | transmembrane protein 65 | 0.024674 |
| SIK3 | SIK family kinase 3 | 0.0245815 |
| UBL3 | ubiquitin-like 3 | 0.0241263 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0239114 |
| SEC24A | SEC24 family member A | 0.0238891 |
| GOLGB1 | golgin B1 | 0.0236679 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0232538 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0227856 |
| TRIM2 | tripartite motif containing 2 | 0.0225709 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0225293 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0223556 |
| CANX | calnexin | 0.022175 |
| IFNGR1 | interferon gamma receptor 1 | 0.0220992 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0220923 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0218013 |
| PMM2 | phosphomannomutase 2 | 0.0215674 |
| USP53 | ubiquitin specific peptidase 53 | 0.0215607 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0212001 |
| SUCO | SUN domain containing ossification factor | 0.0209899 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0207216 |
| EZR | ezrin | 0.020662 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0203411 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.020216 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0199561 |
| TOP1 | topoisomerase (DNA) I | 0.0199352 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0198015 |
| AHI1 | Abelson helper integration site 1 | 0.0197468 |
| COG6 | component of oligomeric golgi complex 6 | 0.0193843 |
| HOMER1 | homer scaffolding protein 1 | 0.0190906 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0190787 |
| MCU | mitochondrial calcium uniporter | 0.0190662 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0189047 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0188118 |
| CDHR2 | cadherin-related family member 2 | 0.0188082 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0185396 |
| LAMB3 | laminin, beta 3 | 0.0183477 |
| NABP1 | nucleic acid binding protein 1 | 0.0183131 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0182402 |
| PRELID2 | PRELI domain containing 2 | 0.0182107 |
| ATF6 | activating transcription factor 6 | 0.0181166 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.018005 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0179915 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0179502 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0177976 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0176931 |
| SERINC5 | serine incorporator 5 | 0.0175253 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0173737 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0173427 |
| RND3 | Rho family GTPase 3 | 0.0172804 |
| SLK | STE20-like kinase | 0.0171037 |
| NEBL | nebulette | 0.0169831 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0167287 |
| COG3 | component of oligomeric golgi complex 3 | 0.0164768 |
| FRMD5 | FERM domain containing 5 | 0.0164347 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0164304 |
| FHIT | fragile histidine triad | 0.0163791 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.151446 |
| LYZ | lysozyme | -0.135218 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.126704 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.120126 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.102351 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.101247 |
| LCN2 | lipocalin 2 | -0.0996237 |
| HLA-B | major histocompatibility complex, class I, B | -0.0984045 |
| B2M | beta-2-microglobulin | -0.0891659 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0818906 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0797728 |
| RPS6 | ribosomal protein S6 | -0.0786661 |
| TMSB10 | thymosin beta 10 | -0.075323 |
| RPL35A | ribosomal protein L35a | -0.0743883 |
| FTL | ferritin, light polypeptide | -0.0682831 |
| PKM | pyruvate kinase, muscle | -0.0644003 |
| TXNIP | thioredoxin interacting protein | -0.0640014 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0633233 |
| EGR1 | early growth response 1 | -0.06147 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0608238 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0606665 |
| MX1 | MX dynamin-like GTPase 1 | -0.0584737 |
| MX2 | MX dynamin-like GTPase 2 | -0.0547522 |
| RPL23 | ribosomal protein L23 | -0.0539881 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0513738 |
| NDRG1 | N-myc downstream regulated 1 | -0.0507886 |
| NPSR1 | neuropeptide S receptor 1 | -0.0500516 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0486174 |
| TNS4 | tensin 4 | -0.0463486 |
| RPLP1 | ribosomal protein, large, P1 | -0.0456767 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0455713 |
| MT2A | metallothionein 2A | -0.0449769 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0436367 |
| SP100 | SP100 nuclear antigen | -0.0432017 |
| XAF1 | XIAP associated factor 1 | -0.0427068 |
| ACTG1 | actin gamma 1 | -0.0424236 |
| RPS8 | ribosomal protein S8 | -0.0421992 |
| HLA-A | major histocompatibility complex, class I, A | -0.040859 |
| PMP22 | peripheral myelin protein 22 | -0.0406053 |
| RPL34 | ribosomal protein L34 | -0.040573 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0399907 |
| HLA-C | major histocompatibility complex, class I, C | -0.0399743 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0398302 |
| S100A6 | S100 calcium binding protein A6 | -0.0397292 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0396295 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0381893 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0379038 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0374594 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0373126 |
| SSH2 | slingshot protein phosphatase 2 | -0.0372166 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0371703 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.037128 |
| ITGA6 | integrin, alpha 6 | -0.0362688 |
| RNF213 | ring finger protein 213 | -0.0362302 |
| RPS29 | ribosomal protein S29 | -0.0362292 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0361722 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0354863 |
| RPS27 | ribosomal protein S27 | -0.0352944 |
| KRT19 | keratin 19, type I | -0.0351034 |
| RPS19 | ribosomal protein S19 | -0.0349755 |
| TPI1 | triosephosphate isomerase 1 | -0.0348137 |
| RIGI | RNA sensor RIG-I | -0.0347166 |
| HLA-E | major histocompatibility complex, class I, E | -0.034306 |
| RPL31 | ribosomal protein L31 | -0.0335507 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0328263 |
| TPM4 | tropomyosin 4 | -0.0327591 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0319876 |
| POTEF | POTE ankyrin domain family, member F | -0.0319529 |
| EPHB2 | EPH receptor B2 | -0.0317732 |
| PERP | PERP, TP53 apoptosis effector | -0.0317324 |
| RPL19 | ribosomal protein L19 | -0.0316749 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0316689 |
| RPL9 | ribosomal protein L9 | -0.0311748 |
| AREG | amphiregulin | -0.0311075 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0310756 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0310373 |
| CST3 | cystatin C | -0.0309343 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0307504 |
| RPS13 | ribosomal protein S13 | -0.03075 |
| CTSD | cathepsin D | -0.0307412 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0305567 |
| S100A9 | S100 calcium binding protein A9 | -0.0304674 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0303302 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0299431 |
| VIM | vimentin | -0.0297052 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0293763 |
| RPL11 | ribosomal protein L11 | -0.0293658 |
| TAOK3 | TAO kinase 3 | -0.0282593 |
| RPL12 | ribosomal protein L12 | -0.0281489 |
| RPS24 | ribosomal protein S24 | -0.0278976 |
| RPLP0 | ribosomal protein, large, P0 | -0.0278254 |
| UBC | ubiquitin C | -0.0277929 |
| RPS3 | ribosomal protein S3 | -0.0277331 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0274605 |
| S100P | S100 calcium binding protein P | -0.0271826 |
| DSTN | destrin (actin depolymerizing factor) | -0.0270973 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0269542 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0264773 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0264537 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0261625 |
