| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Volasertib perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Volasertib_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EZR | ezrin | 0.0819036 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0773617 |
| B2M | beta-2-microglobulin | 0.0709909 |
| TMC5 | transmembrane channel-like 5 | 0.0484539 |
| MYOF | myoferlin | 0.0412559 |
| GDA | guanine deaminase | 0.0388469 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0365377 |
| ASPH | aspartate beta-hydroxylase | 0.0362859 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0353726 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0347446 |
| EFNA5 | ephrin-A5 | 0.0343011 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0336366 |
| AGR3 | anterior gradient 3 | 0.0336125 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0333505 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0304241 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0302094 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0294698 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0289763 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0276628 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0267519 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0260944 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0258645 |
| SEPTIN9 | septin 9 | 0.0245069 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0243321 |
| COBL | cordon-bleu WH2 repeat protein | 0.02427 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0242444 |
| ZNF292 | zinc finger protein 292 | 0.0240451 |
| ANXA1 | annexin A1 | 0.0238594 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0236875 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0236311 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.023273 |
| PCBP2 | poly(rC) binding protein 2 | 0.0230674 |
| LMO7 | LIM domain 7 | 0.0225468 |
| RASEF | RAS and EF-hand domain containing | 0.0224191 |
| RBM47 | RNA binding motif protein 47 | 0.0222055 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0215821 |
| STK24 | serine/threonine kinase 24 | 0.0215731 |
| ANLN | anillin, actin binding protein | 0.0214829 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0212831 |
| PLS1 | plastin 1 | 0.0210228 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0209555 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.020793 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0205322 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0199695 |
| PTK2 | protein tyrosine kinase 2 | 0.0197869 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.019656 |
| SIK3 | SIK family kinase 3 | 0.0194876 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0191758 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0189548 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0189527 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0189063 |
| C12ORF75 | chromosome 12 open reading frame 75 | 0.0188037 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0187928 |
| ANXA11 | annexin A11 | 0.0185233 |
| TSPAN3 | tetraspanin 3 | 0.018431 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0184015 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0182639 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0182165 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0179743 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0178685 |
| MCU | mitochondrial calcium uniporter | 0.0178622 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0178327 |
| ANO6 | anoctamin 6 | 0.0178321 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0177 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0175453 |
| SHROOM3 | shroom family member 3 | 0.017488 |
| DST | dystonin | 0.0174673 |
| RRM2 | ribonucleotide reductase M2 | 0.0174522 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0174398 |
| SGMS2 | sphingomyelin synthase 2 | 0.0174351 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0170882 |
| SMAD3 | SMAD family member 3 | 0.0170633 |
| WWC1 | WW and C2 domain containing 1 | 0.0170623 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0170495 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0169743 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0169198 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0167941 |
| ECT2 | epithelial cell transforming 2 | 0.0167742 |
| PRELID2 | PRELI domain containing 2 | 0.0167083 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0164508 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0164012 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0161187 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0160585 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.015982 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0158957 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0158145 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0154973 |
| ACTN4 | actinin, alpha 4 | 0.0154502 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0153817 |
| RAI1 | retinoic acid induced 1 | 0.0151878 |
| TMSB4X | thymosin beta 4, X-linked | 0.0151845 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0151587 |
| LRRC1 | leucine rich repeat containing 1 | 0.0151454 |
| PLSCR1 | phospholipid scramblase 1 | 0.0149451 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0147934 |
| TPM3 | tropomyosin 3 | 0.0147873 |
| FHL2 | four and a half LIM domains 2 | 0.0147541 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0146365 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0145707 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0145362 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.312653 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.175755 |
| NPSR1 | neuropeptide S receptor 1 | -0.17179 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.131788 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.126559 |
| PTMA | prothymosin, alpha | -0.125205 |
| AGR2 | anterior gradient 2 | -0.120177 |
| FTL | ferritin, light polypeptide | -0.11601 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105339 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.10357 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0798765 |
| TMSB10 | thymosin beta 10 | -0.0700713 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0669196 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0665372 |
| NDRG1 | N-myc downstream regulated 1 | -0.0625444 |
| RPL35A | ribosomal protein L35a | -0.0614831 |
| RPS25 | ribosomal protein S25 | -0.061228 |
| KRT18 | keratin 18, type I | -0.0575399 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0561103 |
| RPS6 | ribosomal protein S6 | -0.0560884 |
| S100P | S100 calcium binding protein P | -0.0559222 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0535441 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0530023 |
| ANXA2 | annexin A2 | -0.0515583 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0497376 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0493744 |
| RPS3 | ribosomal protein S3 | -0.0490287 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0486045 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0485564 |
| AREG | amphiregulin | -0.047958 |
| RPS8 | ribosomal protein S8 | -0.0459981 |
| HM13 | histocompatibility (minor) 13 | -0.0451481 |
| KLHL29 | kelch-like family member 29 | -0.0451093 |
| RPL23 | ribosomal protein L23 | -0.0436832 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0431541 |
| INTS6 | integrator complex subunit 6 | -0.0431526 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.042688 |
| RPS16 | ribosomal protein S16 | -0.0423539 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0422174 |
| RPL37A | ribosomal protein L37a | -0.0420731 |
| H1-0 | H1.0 linker histone | -0.0416615 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0410496 |
| RPS27A | ribosomal protein S27a | -0.0410037 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0409514 |
| CANX | calnexin | -0.0387948 |
| TMEM123 | transmembrane protein 123 | -0.0379725 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0379469 |
| POF1B | premature ovarian failure, 1B | -0.0377162 |
| CUX1 | cut-like homeobox 1 | -0.0368669 |
| FLNB | filamin B, beta | -0.0368013 |
| RPL19 | ribosomal protein L19 | -0.0365542 |
| TES | testin LIM domain protein | -0.0358972 |
| LAMB3 | laminin, beta 3 | -0.0353422 |
| KRT7 | keratin 7, type II | -0.034789 |
| RPL38 | ribosomal protein L38 | -0.0346699 |
| EHBP1 | EH domain binding protein 1 | -0.0343782 |
| AHNAK | AHNAK nucleoprotein | -0.0337301 |
| CCND1 | cyclin D1 | -0.0334565 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0331058 |
| CDK6 | cyclin-dependent kinase 6 | -0.0329886 |
| TFRC | transferrin receptor | -0.0326636 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0325531 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0322963 |
| HDLBP | high density lipoprotein binding protein | -0.0321226 |
| TPM4 | tropomyosin 4 | -0.0318917 |
| UBB | ubiquitin B | -0.0316346 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0316013 |
| ATXN1 | ataxin 1 | -0.031593 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0313511 |
| RPLP1 | ribosomal protein, large, P1 | -0.0309869 |
| RPS24 | ribosomal protein S24 | -0.0309603 |
| ACTG1 | actin gamma 1 | -0.0309252 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0307812 |
| FBXO11 | F-box protein 11 | -0.0307582 |
| HLA-A | major histocompatibility complex, class I, A | -0.0304414 |
| S100A6 | S100 calcium binding protein A6 | -0.0303747 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0301487 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0300813 |
| GNAS | GNAS complex locus | -0.0300706 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0299898 |
| RPL34 | ribosomal protein L34 | -0.0298532 |
| RPS29 | ribosomal protein S29 | -0.0298471 |
| MORF4L2 | mortality factor 4 like 2 | -0.0296239 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0294008 |
| RPL26 | ribosomal protein L26 | -0.0293439 |
| HLA-E | major histocompatibility complex, class I, E | -0.0292326 |
| MTDH | metadherin | -0.0291336 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.02893 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0288106 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0287962 |
| RPL8 | ribosomal protein L8 | -0.0287079 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0285033 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0284929 |
| WDR45B | WD repeat domain 45B | -0.0280901 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0277717 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0277657 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0277502 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0275956 |
| GOLGA4 | golgin A4 | -0.0275797 |
| RPL28 | ribosomal protein L28 | -0.0273124 |
