| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Volasertib perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Volasertib_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.124059 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0941997 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0874721 |
| LMO7 | LIM domain 7 | 0.0626561 |
| MYO1E | myosin IE | 0.062366 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0604666 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0597154 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.054607 |
| B2M | beta-2-microglobulin | 0.0515219 |
| RPS12 | ribosomal protein S12 | 0.0514938 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0510416 |
| ASPH | aspartate beta-hydroxylase | 0.0479476 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0470146 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0455477 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.04433 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0419432 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0410537 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0391825 |
| SIK3 | SIK family kinase 3 | 0.037979 |
| PDLIM5 | PDZ and LIM domain 5 | 0.036925 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0358404 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0341383 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0337153 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0327698 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.032578 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.032416 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.032067 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.031484 |
| EGFR | epidermal growth factor receptor | 0.0314315 |
| RPL14 | ribosomal protein L14 | 0.0308476 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0306272 |
| VEGFA | vascular endothelial growth factor A | 0.0304202 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0298029 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0294577 |
| INTS6 | integrator complex subunit 6 | 0.0291328 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0290543 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.028918 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0288833 |
| SQSTM1 | sequestosome 1 | 0.0286458 |
| CRY1 | cryptochrome circadian clock 1 | 0.0284965 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0278833 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0276762 |
| USP53 | ubiquitin specific peptidase 53 | 0.0273956 |
| BRD2 | bromodomain containing 2 | 0.0272971 |
| TJP1 | tight junction protein 1 | 0.0272057 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0270448 |
| FTL | ferritin, light polypeptide | 0.0269731 |
| MYO5B | myosin VB | 0.0267818 |
| PDZD8 | PDZ domain containing 8 | 0.0265807 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0261109 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0253124 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0251341 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.025089 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0250119 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0249204 |
| GOLGB1 | golgin B1 | 0.0249187 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0248275 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0247309 |
| SVIL | supervillin | 0.0243461 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0242874 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0241854 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0238515 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0236742 |
| TMSB4X | thymosin beta 4, X-linked | 0.0234148 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0233953 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0229352 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0228963 |
| WHRN | whirlin | 0.0227313 |
| AEBP2 | AE binding protein 2 | 0.0227013 |
| RPS17 | ribosomal protein S17 | 0.0226561 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0226316 |
| DIAPH1 | diaphanous-related formin 1 | 0.0224512 |
| FBXO11 | F-box protein 11 | 0.0222735 |
| SMAD2 | SMAD family member 2 | 0.0221912 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0218054 |
| MUC13 | mucin 13, cell surface associated | 0.0217172 |
| FHIT | fragile histidine triad | 0.0215944 |
| SMYD3 | SET and MYND domain containing 3 | 0.0215605 |
| RAD51B | RAD51 paralog B | 0.0213577 |
| RPS25 | ribosomal protein S25 | 0.0212559 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0212287 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0211138 |
| VCL | vinculin | 0.0210884 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.020921 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0204775 |
| SGMS2 | sphingomyelin synthase 2 | 0.0202089 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0198582 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0198197 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0197889 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0197043 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0196429 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.01964 |
| RPL31 | ribosomal protein L31 | 0.0195797 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.01918 |
| RPS8 | ribosomal protein S8 | 0.0191449 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0191237 |
| RPL37A | ribosomal protein L37a | 0.0189959 |
| MCL1 | myeloid cell leukemia 1 | 0.0187925 |
| RND3 | Rho family GTPase 3 | 0.0186897 |
| FNIP1 | folliculin interacting protein 1 | 0.0185951 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.286045 |
| PTMA | prothymosin, alpha | -0.265487 |
| NPSR1 | neuropeptide S receptor 1 | -0.162847 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119024 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.118546 |
| ANXA2 | annexin A2 | -0.110304 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.107095 |
| TNS4 | tensin 4 | -0.106016 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0982897 |
| TMSB10 | thymosin beta 10 | -0.0981525 |
| NDRG1 | N-myc downstream regulated 1 | -0.0938604 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0858505 |
| RNF43 | ring finger protein 43 | -0.0846644 |
| AHNAK | AHNAK nucleoprotein | -0.0821825 |
| FLNB | filamin B, beta | -0.0772197 |
| H1-0 | H1.0 linker histone | -0.0754188 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0748304 |
| FAM13A | family with sequence similarity 13, member A | -0.0691606 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0648709 |
| EREG | epiregulin | -0.0622407 |
| KRT18 | keratin 18, type I | -0.0617018 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.060525 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0598097 |
| GPHN | gephyrin | -0.0592671 |
| ACTN4 | actinin, alpha 4 | -0.0589081 |
| PRSS3 | protease, serine, 3 | -0.0570731 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.056723 |
| EPCAM | epithelial cell adhesion molecule | -0.0558103 |
| RPLP1 | ribosomal protein, large, P1 | -0.0531132 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0526457 |
| FERMT1 | fermitin family member 1 | -0.0515738 |
| OGA | O-GlcNAcase | -0.0508733 |
| RBM39 | RNA binding motif protein 39 | -0.0497436 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0491723 |
| ITGB4 | integrin, beta 4 | -0.0485446 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0482051 |
| GOLGA4 | golgin A4 | -0.0480784 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0479148 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0459581 |
| GDF15 | growth differentiation factor 15 | -0.0455983 |
| PIGR | polymeric immunoglobulin receptor | -0.0450599 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0448161 |
| TXNIP | thioredoxin interacting protein | -0.0430482 |
| S100A6 | S100 calcium binding protein A6 | -0.0425055 |
| ONECUT3 | one cut homeobox 3 | -0.0420972 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0420146 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.041785 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0417503 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0417477 |
| INSIG1 | insulin induced gene 1 | -0.0414102 |
| KIF5B | kinesin family member 5B | -0.0408606 |
| PCDHB16 | protocadherin beta 16 | -0.0406404 |
| RPLP0 | ribosomal protein, large, P0 | -0.0395137 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0394645 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0391044 |
| FNBP1L | formin binding protein 1-like | -0.0380729 |
| MED13L | mediator complex subunit 13-like | -0.0378001 |
| SERINC5 | serine incorporator 5 | -0.0375616 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0370157 |
| WDR45B | WD repeat domain 45B | -0.0368163 |
| AGR2 | anterior gradient 2 | -0.0367894 |
| EXOC1 | exocyst complex component 1 | -0.0365932 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0361536 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0357205 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0356126 |
| RRBP1 | ribosome binding protein 1 | -0.0355967 |
| NFIA | nuclear factor I/A | -0.0352885 |
| LDHA | lactate dehydrogenase A | -0.0344932 |
| USP3 | ubiquitin specific peptidase 3 | -0.0343363 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0341647 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0340292 |
| HMGA1 | high mobility group AT-hook 1 | -0.0338106 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0335095 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0334591 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0334116 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0332217 |
| RPS24 | ribosomal protein S24 | -0.0330132 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0328595 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0328222 |
| TFRC | transferrin receptor | -0.0327023 |
| CANX | calnexin | -0.0324882 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0322864 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0319643 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0318332 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0316407 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0315912 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0306959 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0305079 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0304944 |
| ABHD17C | abhydrolase domain containing 17C | -0.0304656 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0300564 |
| DSG2 | desmoglein 2 | -0.0299314 |
| NF1 | neurofibromin 1 | -0.029677 |
| NRN1 | neuritin 1 | -0.029217 |
| ARF1 | ADP-ribosylation factor 1 | -0.0288567 |
| BCL2L1 | BCL2-like 1 | -0.0287507 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0287428 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0286614 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.028559 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.028397 |
