| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Volasertib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Volasertib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.137672 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.137552 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0991373 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0774432 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0752456 |
| TP63 | tumor protein p63 | 0.0748386 |
| CAPRIN2 | caprin family member 2 | 0.0684089 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0654122 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0607994 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0607975 |
| HOMER1 | homer scaffolding protein 1 | 0.0604531 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0601169 |
| HDAC9 | histone deacetylase 9 | 0.0594222 |
| INTS6 | integrator complex subunit 6 | 0.0514148 |
| RPS12 | ribosomal protein S12 | 0.0509826 |
| FMNL2 | formin-like 2 | 0.0509428 |
| PRELID2 | PRELI domain containing 2 | 0.0470386 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0467236 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.046179 |
| ANK2 | ankyrin 2, neuronal | 0.0460866 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0459243 |
| FNIP1 | folliculin interacting protein 1 | 0.0439779 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0437216 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0435102 |
| MYOF | myoferlin | 0.0429193 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0424982 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0421141 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0419688 |
| CMIP | c-Maf inducing protein | 0.0418073 |
| CADM2 | cell adhesion molecule 2 | 0.0414758 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.040042 |
| RAD51B | RAD51 paralog B | 0.0398944 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.039438 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0393425 |
| FTL | ferritin, light polypeptide | 0.0386329 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0383436 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0369513 |
| PRKCE | protein kinase C, epsilon | 0.0355721 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.035175 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0348758 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0346783 |
| EFNA5 | ephrin-A5 | 0.0337859 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0332021 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.033074 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0329377 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0326768 |
| AEBP2 | AE binding protein 2 | 0.0325822 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0323245 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0320324 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0317915 |
| TNS3 | tensin 3 | 0.0315421 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0312475 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0307098 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0303897 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0300454 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.029996 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0298527 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0295586 |
| RPL37A | ribosomal protein L37a | 0.0294535 |
| RPL31 | ribosomal protein L31 | 0.0293965 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0290343 |
| GPHN | gephyrin | 0.0285661 |
| RPS3 | ribosomal protein S3 | 0.0284586 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0281405 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0279846 |
| DENND1A | DENN/MADD domain containing 1A | 0.0279544 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0274967 |
| NEK10 | NIMA-related kinase 10 | 0.0273643 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0269673 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.0268523 |
| BRD2 | bromodomain containing 2 | 0.0256345 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0254299 |
| MB21D2 | Mab-21 domain containing 2 | 0.0250689 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0249896 |
| JMJD1C | jumonji domain containing 1C | 0.024841 |
| LYST | lysosomal trafficking regulator | 0.02471 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0246944 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0244917 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.024473 |
| RUNX1 | runt-related transcription factor 1 | 0.0243934 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0241706 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0241281 |
| UBAP2 | ubiquitin associated protein 2 | 0.0241203 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0240541 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0240495 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0239829 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0237291 |
| B2M | beta-2-microglobulin | 0.0234139 |
| ZNF638 | zinc finger protein 638 | 0.0233514 |
| EHBP1 | EH domain binding protein 1 | 0.0233349 |
| WDR27 | WD repeat domain 27 | 0.0232543 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.023207 |
| EGFR | epidermal growth factor receptor | 0.0228827 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0228624 |
| RPS6 | ribosomal protein S6 | 0.0225532 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0223993 |
| RPS29 | ribosomal protein S29 | 0.0223951 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0221572 |
| RPS23 | ribosomal protein S23 | 0.0221113 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.022041 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.190932 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.132794 |
| TXNRD1 | thioredoxin reductase 1 | -0.108459 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.106501 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.103739 |
| MT2A | metallothionein 2A | -0.0979249 |
| PTMA | prothymosin, alpha | -0.0843425 |
| RAI1 | retinoic acid induced 1 | -0.082936 |
| CENPF | centromere protein F, 350/400kDa | -0.0723394 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0707235 |
| AHNAK | AHNAK nucleoprotein | -0.0695432 |
| TMSB10 | thymosin beta 10 | -0.0619819 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0591462 |
| ACTG1 | actin gamma 1 | -0.0565844 |
| SRGN | serglycin | -0.0543414 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.052982 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0494428 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0475355 |
| MKI67 | marker of proliferation Ki-67 | -0.0465842 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0458262 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0380861 |
| KLF6 | Kruppel-like factor 6 | -0.0369118 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0363973 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0349907 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0338844 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0335701 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0330284 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0328907 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0325725 |
| ZNF217 | zinc finger protein 217 | -0.0322547 |
| EZR | ezrin | -0.0311918 |
| RIGI | RNA sensor RIG-I | -0.0311231 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.031115 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0306469 |
| RTN4 | reticulon 4 | -0.0297239 |
| EMP1 | epithelial membrane protein 1 | -0.0292585 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0289008 |
| HMGA1 | high mobility group AT-hook 1 | -0.0288562 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0287575 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0287039 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0281109 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0277962 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0277081 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0276032 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0274844 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0274404 |
| TMSB4X | thymosin beta 4, X-linked | -0.0273366 |
| MT1E | metallothionein 1E | -0.0272787 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0269142 |
| LDHA | lactate dehydrogenase A | -0.0267875 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0266797 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0265918 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0262384 |
| ANLN | anillin, actin binding protein | -0.0260155 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0260134 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.025942 |
| ZFR | zinc finger RNA binding protein | -0.0255615 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0254477 |
| TOP1 | topoisomerase (DNA) I | -0.0251986 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.025162 |
| KIF14 | kinesin family member 14 | -0.0249723 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0248521 |
| HJURP | Holliday junction recognition protein | -0.0244233 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | -0.0244125 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0243202 |
| TPX2 | TPX2, microtubule-associated | -0.0241948 |
| CANX | calnexin | -0.024119 |
| TMEM123 | transmembrane protein 123 | -0.0240841 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0240723 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0240461 |
| HMGB2 | high mobility group box 2 | -0.023993 |
| RGS4 | regulator of G-protein signaling 4 | -0.0239537 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0238747 |
| ANXA1 | annexin A1 | -0.0238009 |
| RPL23 | ribosomal protein L23 | -0.0235772 |
| TPM4 | tropomyosin 4 | -0.0235104 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.023486 |
| CENPE | centromere protein E, 312kDa | -0.0234831 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.023279 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0230637 |
| TMEM41B | transmembrane protein 41B | -0.0230542 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0228424 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0228032 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0227902 |
| XPO1 | exportin 1 | -0.0226009 |
| EP300 | E1A binding protein p300 | -0.0225966 |
| SOCS6 | suppressor of cytokine signaling 6 | -0.02212 |
| FERMT1 | fermitin family member 1 | -0.0219909 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0217869 |
| DIAPH3 | diaphanous-related formin 3 | -0.0216891 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.021622 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0215486 |
| ECT2 | epithelial cell transforming 2 | -0.0215213 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0215093 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0213878 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0212001 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0211585 |
| SMAD3 | SMAD family member 3 | -0.0209885 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0208552 |
| YBX3 | Y box binding protein 3 | -0.0208509 |
