| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Volasertib perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Volasertib_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.11854 |
| SLTM | SAFB-like, transcription modulator | 0.114902 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.10814 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.104723 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.103491 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0979871 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0936646 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.092872 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0808963 |
| DTNA | dystrobrevin, alpha | 0.0770266 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0764465 |
| INTS6 | integrator complex subunit 6 | 0.0760608 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0735513 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0713677 |
| RUNX1 | runt-related transcription factor 1 | 0.0671018 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0646643 |
| SMAD3 | SMAD family member 3 | 0.0627834 |
| ENO1 | enolase 1, (alpha) | 0.0625891 |
| GPC6 | glypican 6 | 0.0624716 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0607553 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0601123 |
| SPAG9 | sperm associated antigen 9 | 0.0592283 |
| ARRDC3 | arrestin domain containing 3 | 0.058419 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0581637 |
| B2M | beta-2-microglobulin | 0.0577418 |
| SEC61G | Sec61 gamma subunit | 0.0568553 |
| FNIP1 | folliculin interacting protein 1 | 0.056625 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0560703 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0554385 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0549224 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0547561 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0540926 |
| JMJD1C | jumonji domain containing 1C | 0.0539823 |
| MYOF | myoferlin | 0.0535117 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0532595 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.052936 |
| TPD52 | tumor protein D52 | 0.0524371 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0520291 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0513317 |
| GPHN | gephyrin | 0.0512796 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0508537 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0504497 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0496862 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0492969 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0485677 |
| PCBP2 | poly(rC) binding protein 2 | 0.0483359 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0466405 |
| PDE8A | phosphodiesterase 8A | 0.0464949 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0462347 |
| NPTN | neuroplastin | 0.0460941 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0458373 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0456372 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0453845 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0451627 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0450423 |
| MCL1 | myeloid cell leukemia 1 | 0.0449527 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0438497 |
| BRD2 | bromodomain containing 2 | 0.043183 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0421097 |
| UVRAG | UV radiation resistance associated | 0.0419085 |
| ZNF292 | zinc finger protein 292 | 0.0410203 |
| RNF145 | ring finger protein 145 | 0.0410099 |
| HOMER1 | homer scaffolding protein 1 | 0.0406855 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0406358 |
| ANKRD11 | ankyrin repeat domain 11 | 0.040309 |
| RPS3 | ribosomal protein S3 | 0.0398645 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0397464 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0392176 |
| HELZ | helicase with zinc finger | 0.0390647 |
| PTK2 | protein tyrosine kinase 2 | 0.039011 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0387402 |
| USP53 | ubiquitin specific peptidase 53 | 0.0384513 |
| ZNF638 | zinc finger protein 638 | 0.0380153 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0374456 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0364281 |
| ANO6 | anoctamin 6 | 0.0363581 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0359588 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0356452 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0355028 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0351376 |
| USP34 | ubiquitin specific peptidase 34 | 0.0348168 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0347739 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0347094 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0344399 |
| ANXA5 | annexin A5 | 0.0336834 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0335918 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0329779 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0329338 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0328914 |
| MYO5B | myosin VB | 0.0323359 |
| PAPOLA | poly(A) polymerase alpha | 0.0322383 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0321501 |
| GRAMD1B | GRAM domain containing 1B | 0.0321148 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0320147 |
| ATP13A3 | ATPase type 13A3 | 0.0319113 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0318418 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0317432 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0313326 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0312979 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0312733 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.129721 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.109948 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.100518 |
| OSMR | oncostatin M receptor | -0.0924883 |
| TMSB10 | thymosin beta 10 | -0.0766081 |
| LAMA4 | laminin, alpha 4 | -0.0751883 |
| LAMC2 | laminin, gamma 2 | -0.075146 |
| EGR1 | early growth response 1 | -0.0742994 |
| ACTG1 | actin gamma 1 | -0.0719046 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0685963 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0591099 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0558263 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0527476 |
| AHNAK | AHNAK nucleoprotein | -0.0523347 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0481181 |
| MKI67 | marker of proliferation Ki-67 | -0.0471904 |
| LMO7 | LIM domain 7 | -0.043817 |
| KRT18 | keratin 18, type I | -0.0433146 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0427963 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.041265 |
| KRT7 | keratin 7, type II | -0.04067 |
| H1-0 | H1.0 linker histone | -0.0365435 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0359122 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0356363 |
| CST3 | cystatin C | -0.0354078 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0349867 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0328523 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0325273 |
| GM2A | GM2 ganglioside activator | -0.0316911 |
| AGR2 | anterior gradient 2 | -0.0311226 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0305837 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0299009 |
| LDHA | lactate dehydrogenase A | -0.0295758 |
| VCL | vinculin | -0.0290669 |
| SMIM14 | small integral membrane protein 14 | -0.0284082 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0281302 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0279534 |
| CCND1 | cyclin D1 | -0.0278947 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0278822 |
| SDC1 | syndecan 1 | -0.0275567 |
| POTEF | POTE ankyrin domain family, member F | -0.0270787 |
| PERP | PERP, TP53 apoptosis effector | -0.0265453 |
| S100A11 | S100 calcium binding protein A11 | -0.0253841 |
| FRMD4B | FERM domain containing 4B | -0.0251599 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0251572 |
| MGAT4C | MGAT4 family, member C | -0.0251455 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0251145 |
| ANXA2 | annexin A2 | -0.02505 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0249649 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0244202 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0241297 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0238384 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0236579 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0230205 |
| RIN2 | Ras and Rab interactor 2 | -0.0222654 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0221878 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0220178 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0216401 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.020734 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0206638 |
| PKM | pyruvate kinase, muscle | -0.0204636 |
| DSPP | dentin sialophosphoprotein | -0.0202783 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0200404 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0198917 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0197727 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0196416 |
| HMGA1 | high mobility group AT-hook 1 | -0.0195619 |
| SCEL | sciellin | -0.0195502 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0194209 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -0.019405 |
| ABLIM1 | actin binding LIM protein 1 | -0.0189632 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0188066 |
| TKT | transketolase | -0.0184006 |
| KRT19 | keratin 19, type I | -0.0181813 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | -0.0180691 |
| FLNB | filamin B, beta | -0.017827 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0174902 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0174897 |
| PCED1B | PC-esterase domain containing 1B | -0.0172575 |
| CAV2 | caveolin 2 | -0.0172343 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0170948 |
| TPM4 | tropomyosin 4 | -0.0167348 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0164423 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0162944 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0162796 |
| NTN4 | netrin 4 | -0.0161355 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0160081 |
| S100A6 | S100 calcium binding protein A6 | -0.0160076 |
| S100A9 | S100 calcium binding protein A9 | -0.0159969 |
| CPE | carboxypeptidase E | -0.0159149 |
| JUP | junction plakoglobin | -0.015711 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0156668 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.015654 |
| HDLBP | high density lipoprotein binding protein | -0.0155294 |
| S100A10 | S100 calcium binding protein A10 | -0.0154591 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0153901 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0153673 |
| KLHL5 | kelch-like family member 5 | -0.0152171 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0151583 |
| SYAP1 | synapse associated protein 1 | -0.0150418 |
