| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Volasertib perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
114 genes differentially expressed following the Volasertib_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | 0.181626 |
| FN1 | fibronectin 1 | 0.175784 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.157352 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.130163 |
| DIAPH2 | diaphanous-related formin 2 | 0.1072 |
| SBF2 | SET binding factor 2 | 0.10426 |
| EFNA5 | ephrin-A5 | 0.10266 |
| DST | dystonin | 0.102097 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.09947 |
| LMO7 | LIM domain 7 | 0.0952104 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0949185 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0934891 |
| SMYD3 | SET and MYND domain containing 3 | 0.092321 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0891361 |
| ASPH | aspartate beta-hydroxylase | 0.088539 |
| PTK2 | protein tyrosine kinase 2 | 0.0869612 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0854635 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0744745 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0714217 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0678442 |
| ACTN4 | actinin, alpha 4 | 0.0640993 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0637852 |
| PRELID2 | PRELI domain containing 2 | 0.0608736 |
| TNS3 | tensin 3 | 0.0598099 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0578149 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0573947 |
| PRKCE | protein kinase C, epsilon | 0.051875 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0510445 |
| PKM | pyruvate kinase, muscle | 0.0492738 |
| UBC | ubiquitin C | 0.0467871 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0460798 |
| RUNX1 | runt-related transcription factor 1 | 0.043801 |
| JMJD1C | jumonji domain containing 1C | 0.0297244 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0293144 |
| ZNF292 | zinc finger protein 292 | 0.028685 |
| RPL12 | ribosomal protein L12 | 0.0284991 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0277546 |
| RPL23 | ribosomal protein L23 | 0.0267808 |
| CD2AP | CD2-associated protein | 0.0243922 |
| DTNA | dystrobrevin, alpha | 0.0209041 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0205364 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.019339 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0190168 |
| KIAA1217 | KIAA1217 | 0.0180557 |
| CORO1C | coronin, actin binding protein, 1C | 0.0162266 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0152965 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0106841 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00932746 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.00854821 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.00831063 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.00784283 |
| FMNL2 | formin-like 2 | 0.00688073 |
| NUP58 | nucleoporin 58 | 0.0061899 |
| CCNI | cyclin I | 0.00616754 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0055703 |
| GPC6 | glypican 6 | 0.00351052 |
| RPL37 | ribosomal protein L37 | 0.00302373 |
| CFAP251 | cilia and flagella associated protein 251 | 8.90692E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.287286 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.183924 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.177587 |
| PTMA | prothymosin, alpha | -0.172296 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.147896 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.146884 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.143084 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.130418 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.125826 |
| RORA | RAR-related orphan receptor A | -0.118874 |
| FNDC3B | fibronectin type III domain containing 3B | -0.113846 |
| NDRG1 | N-myc downstream regulated 1 | -0.110691 |
| IGF2 | insulin-like growth factor 2 | -0.100281 |
| RPS6 | ribosomal protein S6 | -0.0964114 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0949282 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0900537 |
| VIM | vimentin | -0.0807239 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0779352 |
| ANXA2 | annexin A2 | -0.0742154 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0676934 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.066898 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0624336 |
| RPS27A | ribosomal protein S27a | -0.0567131 |
| LDHA | lactate dehydrogenase A | -0.056427 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.054752 |
| PRRC2C | proline-rich coiled-coil 2C | -0.052832 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0516245 |
| FTL | ferritin, light polypeptide | -0.0474021 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0462316 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0460518 |
| ZNF638 | zinc finger protein 638 | -0.0451611 |
| USP32 | ubiquitin specific peptidase 32 | -0.0399227 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.035842 |
| FNIP1 | folliculin interacting protein 1 | -0.0346255 |
| FLNB | filamin B, beta | -0.0331096 |
| TMSB10 | thymosin beta 10 | -0.0324202 |
| WAC | WW domain containing adaptor with coiled-coil | -0.030896 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0258174 |
| RLF | rearranged L-myc fusion | -0.022654 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0224524 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0211546 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.019969 |
| ACTG1 | actin gamma 1 | -0.0193916 |
| ERBIN | erbb2 interacting protein | -0.0184224 |
| RTN4 | reticulon 4 | -0.0177061 |
| RPS3 | ribosomal protein S3 | -0.0139919 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0132509 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0132296 |
| PGK1 | phosphoglycerate kinase 1 | -0.0115081 |
| PARD3 | par-3 family cell polarity regulator | -0.00783377 |
| KCMF1 | potassium channel modulatory factor 1 | -0.00769557 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.00536482 |
| HDAC9 | histone deacetylase 9 | -0.00510042 |
| NF1 | neurofibromin 1 | -0.00338514 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.00189825 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -5.01732E-4 |
