| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Volasertib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Volasertib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.175339 |
| HDAC9 | histone deacetylase 9 | 0.0905525 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0713434 |
| B2M | beta-2-microglobulin | 0.049467 |
| ZNF608 | zinc finger protein 608 | 0.0462333 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0448655 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0441201 |
| EZR | ezrin | 0.0427033 |
| MACROD2 | MACRO domain containing 2 | 0.0425345 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0409313 |
| SMYD3 | SET and MYND domain containing 3 | 0.0405856 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0405362 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0377063 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0373623 |
| PRELID2 | PRELI domain containing 2 | 0.0362653 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0359222 |
| PDGFC | platelet derived growth factor C | 0.0308094 |
| RPL3 | ribosomal protein L3 | 0.0304597 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0297494 |
| TMEM65 | transmembrane protein 65 | 0.0296336 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0293392 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0276246 |
| DUSP4 | dual specificity phosphatase 4 | 0.0272418 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0261009 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0259917 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0259275 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0258076 |
| USP34 | ubiquitin specific peptidase 34 | 0.0256202 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0253056 |
| TXNRD1 | thioredoxin reductase 1 | 0.0251607 |
| RPL14 | ribosomal protein L14 | 0.0249254 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0241854 |
| TRIM24 | tripartite motif containing 24 | 0.0238621 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0233909 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0232789 |
| PYGB | phosphorylase, glycogen; brain | 0.0232557 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0230886 |
| RPS2 | ribosomal protein S2 | 0.0225566 |
| SBF2 | SET binding factor 2 | 0.0218948 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0218468 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0217543 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0215835 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0215522 |
| ZNF148 | zinc finger protein 148 | 0.0215488 |
| MYO5C | myosin VC | 0.0215481 |
| CRY1 | cryptochrome circadian clock 1 | 0.0214641 |
| MEIS2 | Meis homeobox 2 | 0.0212883 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0211357 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0208329 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0208139 |
| DGKH | diacylglycerol kinase, eta | 0.0206802 |
| FOXP1 | forkhead box P1 | 0.0206627 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0205467 |
| MLIP | muscular LMNA-interacting protein | 0.020535 |
| APP | amyloid beta (A4) precursor protein | 0.020527 |
| JMJD1C | jumonji domain containing 1C | 0.0204929 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0203029 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0202994 |
| AMOTL2 | angiomotin like 2 | 0.0201391 |
| ATXN1 | ataxin 1 | 0.0201293 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0198484 |
| ZNF292 | zinc finger protein 292 | 0.0196961 |
| USP47 | ubiquitin specific peptidase 47 | 0.0196506 |
| ITGA6 | integrin, alpha 6 | 0.0195619 |
| CORO1C | coronin, actin binding protein, 1C | 0.0194397 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0193917 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.019355 |
| FNIP1 | folliculin interacting protein 1 | 0.0190979 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0190332 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0189503 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0188983 |
| PTK2 | protein tyrosine kinase 2 | 0.0188724 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0188624 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0187761 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0187159 |
| KIAA1328 | KIAA1328 | 0.0184405 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0182776 |
| METTL15 | methyltransferase like 15 | 0.0182684 |
| FHIT | fragile histidine triad | 0.0181257 |
| YLPM1 | YLP motif containing 1 | 0.0179572 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0178421 |
| PCBP2 | poly(rC) binding protein 2 | 0.0178301 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.017654 |
| ANK2 | ankyrin 2, neuronal | 0.0176442 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0173452 |
| FMN1 | formin 1 | 0.0171388 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0169867 |
| PLK2 | polo-like kinase 2 | 0.0169597 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0165978 |
| ERBIN | erbb2 interacting protein | 0.0165872 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0162649 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0162322 |
| TMEM14B | transmembrane protein 14B | 0.0162176 |
| LRRC7 | leucine rich repeat containing 7 | 0.0158257 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0158244 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0157675 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0156969 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0156102 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0156039 |
| NRDC | nardilysin convertase | 0.0155274 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.397583 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.298006 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.139665 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.136178 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.116073 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.111353 |
| AHNAK | AHNAK nucleoprotein | -0.094165 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0792673 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0778211 |
| RPS6 | ribosomal protein S6 | -0.0773936 |
| RPL35A | ribosomal protein L35a | -0.0736898 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0728245 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0676656 |
| BMP10 | bone morphogenetic protein 10 | -0.0655743 |
| ACTG1 | actin gamma 1 | -0.0646919 |
| RPS8 | ribosomal protein S8 | -0.0607908 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0593376 |
| RPLP1 | ribosomal protein, large, P1 | -0.0590907 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0573444 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0518844 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0501009 |
| CCND1 | cyclin D1 | -0.0471041 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0459739 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0457341 |
| RPL34 | ribosomal protein L34 | -0.043986 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0430277 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0429397 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0423504 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0418902 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0382853 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0379681 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.037267 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.036541 |
| GNAS | GNAS complex locus | -0.0365098 |
| LDHA | lactate dehydrogenase A | -0.0362131 |
| S100A4 | S100 calcium binding protein A4 | -0.0350991 |
| PFN1 | profilin 1 | -0.0339061 |
| DIAPH3 | diaphanous-related formin 3 | -0.0336419 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0334093 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0328598 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.032789 |
| S100A6 | S100 calcium binding protein A6 | -0.0327473 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0322459 |
| RPS19 | ribosomal protein S19 | -0.031754 |
| RPS25 | ribosomal protein S25 | -0.0315584 |
| RPL19 | ribosomal protein L19 | -0.0314055 |
| GLI2 | GLI family zinc finger 2 | -0.0312223 |
| S100A10 | S100 calcium binding protein A10 | -0.0305498 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.029912 |
| TPI1 | triosephosphate isomerase 1 | -0.029869 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0296327 |
| POTEF | POTE ankyrin domain family, member F | -0.029505 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0294416 |
| RPLP2 | ribosomal protein, large, P2 | -0.0293093 |
| MKI67 | marker of proliferation Ki-67 | -0.0288404 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0286409 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0283017 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.028154 |
| MAP4 | microtubule-associated protein 4 | -0.0274852 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0273349 |
| S100A9 | S100 calcium binding protein A9 | -0.0271757 |
| RPS24 | ribosomal protein S24 | -0.0270368 |
| RPL31 | ribosomal protein L31 | -0.0269277 |
| RPL35 | ribosomal protein L35 | -0.0267543 |
| ZNF217 | zinc finger protein 217 | -0.0267504 |
| HMGB1 | high mobility group box 1 | -0.0262163 |
| RPL7A | ribosomal protein L7a | -0.0261456 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0259572 |
| RPL26 | ribosomal protein L26 | -0.0257671 |
| RPL12 | ribosomal protein L12 | -0.0255741 |
| PGK1 | phosphoglycerate kinase 1 | -0.025285 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0251159 |
| TPM4 | tropomyosin 4 | -0.0249508 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0249005 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0246745 |
| RPLP0 | ribosomal protein, large, P0 | -0.0246064 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0241675 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0241608 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0238476 |
| CCNI | cyclin I | -0.0236174 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0235424 |
| RPS14 | ribosomal protein S14 | -0.0234904 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0230034 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0229942 |
| NFIA | nuclear factor I/A | -0.0225816 |
| HMGA1 | high mobility group AT-hook 1 | -0.0223854 |
| NEBL | nebulette | -0.0222744 |
| RPL10A | ribosomal protein L10a | -0.0221753 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.021625 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0216092 |
| TUBA1B | tubulin, alpha 1b | -0.0212243 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0210921 |
| RPS16 | ribosomal protein S16 | -0.0209519 |
| DEK | DEK proto-oncogene | -0.0207931 |
| HJURP | Holliday junction recognition protein | -0.0206843 |
| ONECUT2 | one cut homeobox 2 | -0.0206431 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0204807 |
| RPL18 | ribosomal protein L18 | -0.0203945 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0202639 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0202579 |
