| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Volasertib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Volasertib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.141362 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.126247 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.122906 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.10121 |
| GLIS3 | GLIS family zinc finger 3 | 0.0970872 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.09116 |
| PDE10A | phosphodiesterase 10A | 0.0873084 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0856422 |
| HMGA2 | high mobility group AT-hook 2 | 0.0855613 |
| VCAN | versican | 0.0818642 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0814233 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0800469 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0787009 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.07807 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0775745 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0760319 |
| CDH13 | cadherin 13 | 0.0748697 |
| FNIP1 | folliculin interacting protein 1 | 0.0708685 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0707853 |
| RND3 | Rho family GTPase 3 | 0.0665636 |
| GPC6 | glypican 6 | 0.065811 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0622528 |
| ASPH | aspartate beta-hydroxylase | 0.0570219 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0546318 |
| TMSB4X | thymosin beta 4, X-linked | 0.0540356 |
| INTS6 | integrator complex subunit 6 | 0.0531588 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0527322 |
| ATXN1 | ataxin 1 | 0.0527302 |
| SMAD3 | SMAD family member 3 | 0.0524429 |
| KYNU | kynureninase | 0.0510087 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0500472 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0491384 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0483865 |
| GOLGB1 | golgin B1 | 0.0482265 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0478582 |
| SQSTM1 | sequestosome 1 | 0.0475379 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0469554 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.045851 |
| TMEM132D | transmembrane protein 132D | 0.044256 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0428146 |
| PHF3 | PHD finger protein 3 | 0.0419456 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0419154 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0417895 |
| CANX | calnexin | 0.0416292 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.041356 |
| DST | dystonin | 0.0412895 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0407584 |
| SMYD3 | SET and MYND domain containing 3 | 0.040497 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0403832 |
| EFNA5 | ephrin-A5 | 0.0398773 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.039853 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0398486 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.039295 |
| AHNAK | AHNAK nucleoprotein | 0.0392935 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0387796 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0381953 |
| AFF3 | AF4/FMR2 family, member 3 | 0.038117 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0380903 |
| TNS3 | tensin 3 | 0.0380583 |
| COL5A1 | collagen, type V, alpha 1 | 0.0379393 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0375303 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0370933 |
| EGFR | epidermal growth factor receptor | 0.0366103 |
| APP | amyloid beta (A4) precursor protein | 0.0359223 |
| B2M | beta-2-microglobulin | 0.0356911 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.034482 |
| DUSP10 | dual specificity phosphatase 10 | 0.0344046 |
| RPL14 | ribosomal protein L14 | 0.0339156 |
| VEGFA | vascular endothelial growth factor A | 0.0339111 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0336824 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0328978 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0327052 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0318456 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0317554 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0311508 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0311459 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0306914 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0306874 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0305514 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0302863 |
| MLPH | melanophilin | 0.0296547 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0291729 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0289499 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.028947 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0285724 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0283831 |
| EXOC4 | exocyst complex component 4 | 0.0279616 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0275413 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0274346 |
| RUNX1 | runt-related transcription factor 1 | 0.0266499 |
| PCBP3 | poly(rC) binding protein 3 | 0.0266458 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0261669 |
| EHBP1 | EH domain binding protein 1 | 0.0260543 |
| RAD51B | RAD51 paralog B | 0.0260042 |
| FAM20C | family with sequence similarity 20, member C | 0.0259722 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0258977 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0257405 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0255937 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0255475 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0252866 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.186199 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.173089 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.112791 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.109195 |
| TMSB10 | thymosin beta 10 | -0.102655 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0962144 |
| MT2A | metallothionein 2A | -0.0899757 |
| FTL | ferritin, light polypeptide | -0.0898902 |
| FN1 | fibronectin 1 | -0.0843702 |
| PTMA | prothymosin, alpha | -0.0707397 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0675116 |
| RPS6 | ribosomal protein S6 | -0.063881 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0597445 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0560012 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0550714 |
| RTN4 | reticulon 4 | -0.0513107 |
| HLA-B | major histocompatibility complex, class I, B | -0.049533 |
| RPL35A | ribosomal protein L35a | -0.0489278 |
| EGR1 | early growth response 1 | -0.0471418 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.046418 |
| ADM | adrenomedullin | -0.0448783 |
| COL1A1 | collagen, type I, alpha 1 | -0.0426131 |
| CCNL1 | cyclin L1 | -0.0425087 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0424845 |
| HMGA1 | high mobility group AT-hook 1 | -0.0412686 |
| CENPF | centromere protein F, 350/400kDa | -0.0406201 |
| TXNIP | thioredoxin interacting protein | -0.0384087 |
| NDRG1 | N-myc downstream regulated 1 | -0.0370745 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0368298 |
| RPS23 | ribosomal protein S23 | -0.0361596 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0361406 |
| RPS19 | ribosomal protein S19 | -0.0361289 |
| GNAS | GNAS complex locus | -0.0358988 |
| RPLP1 | ribosomal protein, large, P1 | -0.035608 |
| RPL23 | ribosomal protein L23 | -0.0353986 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0347414 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0345591 |
| PFN1 | profilin 1 | -0.0344949 |
| KLF6 | Kruppel-like factor 6 | -0.0339656 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0334132 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0326104 |
| TAPBP | TAP binding protein (tapasin) | -0.0325824 |
| TMEM41B | transmembrane protein 41B | -0.0324316 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0322862 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0317013 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0315225 |
| S100A9 | S100 calcium binding protein A9 | -0.0313574 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0312774 |
| RPL35 | ribosomal protein L35 | -0.0302917 |
| POTEF | POTE ankyrin domain family, member F | -0.0295295 |
| PCBP2 | poly(rC) binding protein 2 | -0.029301 |
| CTSD | cathepsin D | -0.0291281 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0288725 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0288665 |
| RPS24 | ribosomal protein S24 | -0.0274865 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0273922 |
| DEK | DEK proto-oncogene | -0.0273446 |
| RPL36 | ribosomal protein L36 | -0.0271601 |
| RPL32 | ribosomal protein L32 | -0.0271053 |
| PHIP | pleckstrin homology domain interacting protein | -0.0270568 |
| RPS4X | ribosomal protein S4, X-linked | -0.0270491 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0269753 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0269628 |
| RPL9 | ribosomal protein L9 | -0.0268562 |
| ZNF292 | zinc finger protein 292 | -0.0267854 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0265108 |
| RPLP0 | ribosomal protein, large, P0 | -0.0262935 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0258536 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0256684 |
| RPLP2 | ribosomal protein, large, P2 | -0.0255163 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0255054 |
| UBC | ubiquitin C | -0.0254559 |
| FOSL1 | FOS-like antigen 1 | -0.0251257 |
| ARF4 | ADP-ribosylation factor 4 | -0.025084 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0247803 |
| RPL19 | ribosomal protein L19 | -0.0243412 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0243055 |
| RPS14 | ribosomal protein S14 | -0.0241186 |
| MKI67 | marker of proliferation Ki-67 | -0.0239219 |
| RPL11 | ribosomal protein L11 | -0.0238621 |
| TPX2 | TPX2, microtubule-associated | -0.0236011 |
| H3-3B | H3.3 histone B | -0.0235571 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.023474 |
| WASF2 | WAS protein family, member 2 | -0.0232601 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0232461 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0230355 |
| ATP13A3 | ATPase type 13A3 | -0.0229989 |
| DSTN | destrin (actin depolymerizing factor) | -0.0229778 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0229533 |
| COL1A2 | collagen, type I, alpha 2 | -0.022849 |
| WDR45B | WD repeat domain 45B | -0.0226721 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0226383 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0226316 |
| RPS11 | ribosomal protein S11 | -0.0226218 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0225687 |
| FAM13A | family with sequence similarity 13, member A | -0.0224289 |
| NKTR | natural killer cell triggering receptor | -0.0219403 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0218191 |
| FRMD4A | FERM domain containing 4A | -0.0217913 |
| RPS15 | ribosomal protein S15 | -0.0217702 |
