| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Volasertib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Volasertib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.171896 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.137728 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.133012 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.110633 |
| FNDC3B | fibronectin type III domain containing 3B | 0.103892 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0985692 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0967303 |
| INTS6 | integrator complex subunit 6 | 0.0938589 |
| FNIP1 | folliculin interacting protein 1 | 0.0823927 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0765892 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0761027 |
| SMYD3 | SET and MYND domain containing 3 | 0.0756454 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0731605 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0689081 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0689028 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.068303 |
| PRKCA | protein kinase C, alpha | 0.0681219 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0645375 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0639169 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0631724 |
| FMNL2 | formin-like 2 | 0.0618595 |
| DTNA | dystrobrevin, alpha | 0.059317 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0590768 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0558804 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0556832 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.055333 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0549622 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0525929 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.05158 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0506846 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0502483 |
| PKM | pyruvate kinase, muscle | 0.0489251 |
| PRELID2 | PRELI domain containing 2 | 0.0475969 |
| RUNX1 | runt-related transcription factor 1 | 0.0475554 |
| ANO6 | anoctamin 6 | 0.0474793 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0469906 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0465156 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0460608 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0454856 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0454559 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.044214 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0430092 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0415339 |
| ENO1 | enolase 1, (alpha) | 0.0411235 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.041052 |
| GPHN | gephyrin | 0.0398051 |
| ZNF638 | zinc finger protein 638 | 0.0396931 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0396627 |
| OXSR1 | oxidative stress responsive 1 | 0.0391115 |
| NUP58 | nucleoporin 58 | 0.0389935 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0386851 |
| SEC24A | SEC24 family member A | 0.0385426 |
| SQSTM1 | sequestosome 1 | 0.0380946 |
| GPATCH2L | G patch domain containing 2-like | 0.0379313 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0377551 |
| EZR | ezrin | 0.0375922 |
| MCL1 | myeloid cell leukemia 1 | 0.0372596 |
| TLE4 | transducin-like enhancer of split 4 | 0.0371413 |
| USP34 | ubiquitin specific peptidase 34 | 0.0363565 |
| ASPH | aspartate beta-hydroxylase | 0.0362638 |
| GOLGB1 | golgin B1 | 0.0357439 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.034865 |
| B2M | beta-2-microglobulin | 0.0347003 |
| IPO7 | importin 7 | 0.0343992 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0343193 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0341856 |
| GOLGA4 | golgin A4 | 0.0340254 |
| SIK2 | salt-inducible kinase 2 | 0.0339371 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0338298 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0336818 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.033655 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0335327 |
| JMJD1C | jumonji domain containing 1C | 0.0335316 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0334463 |
| ANXA1 | annexin A1 | 0.0328691 |
| TAOK1 | TAO kinase 1 | 0.0328382 |
| SIK3 | SIK family kinase 3 | 0.0323899 |
| RPS12 | ribosomal protein S12 | 0.0318167 |
| TBC1D5 | TBC1 domain family, member 5 | 0.031797 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0311754 |
| BRD2 | bromodomain containing 2 | 0.0311222 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0311205 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0308894 |
| ELOVL7 | ELOVL fatty acid elongase 7 | 0.0308819 |
| HSPA8 | heat shock 70kDa protein 8 | 0.030778 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0306951 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0306441 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0306017 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0301074 |
| ADIPOR2 | adiponectin receptor 2 | 0.0300866 |
| CEP250 | centrosomal protein 250kDa | 0.0300844 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0300788 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0300188 |
| MYOF | myoferlin | 0.0299107 |
| LRRC49 | leucine rich repeat containing 49 | 0.0299095 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.029735 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0296433 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0295471 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0294506 |
| PTK2 | protein tyrosine kinase 2 | 0.0292553 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.109911 |
| TMSB10 | thymosin beta 10 | -0.0868869 |
| AHNAK | AHNAK nucleoprotein | -0.0644399 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0634524 |
| MT2A | metallothionein 2A | -0.0580318 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0538302 |
| RPLP1 | ribosomal protein, large, P1 | -0.0523936 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0498606 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0495177 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0494772 |
| DNER | delta/notch-like EGF repeat containing | -0.0479292 |
| HMGA2 | high mobility group AT-hook 2 | -0.0472619 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0445149 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0444536 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0442995 |
| PTMA | prothymosin, alpha | -0.0441325 |
| IGF2 | insulin-like growth factor 2 | -0.0414728 |
| RBM39 | RNA binding motif protein 39 | -0.0399179 |
| UBB | ubiquitin B | -0.0396375 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.039327 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0389039 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0388101 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0374653 |
| HLA-C | major histocompatibility complex, class I, C | -0.0368268 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0364861 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0360877 |
| TPM4 | tropomyosin 4 | -0.0349793 |
| NALCN | sodium leak channel, non selective | -0.0347417 |
| NDRG1 | N-myc downstream regulated 1 | -0.0345127 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0344233 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0339718 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.031807 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0313894 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0310765 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0310495 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0310017 |
| RPL34 | ribosomal protein L34 | -0.0307719 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0307382 |
| RNF213 | ring finger protein 213 | -0.0304477 |
| RPL35A | ribosomal protein L35a | -0.0303914 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0299375 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0298608 |
| RIGI | RNA sensor RIG-I | -0.0295824 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0291749 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0288067 |
| DEK | DEK proto-oncogene | -0.0285162 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.02841 |
| EFNA5 | ephrin-A5 | -0.0282323 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0279104 |
| RIN2 | Ras and Rab interactor 2 | -0.0278222 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0274613 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0260762 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0260369 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0260175 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0259174 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0258021 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.0256772 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0254572 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0249804 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0249072 |
| LAMA5 | laminin, alpha 5 | -0.0243682 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0243597 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0241634 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0240329 |
| SEPTIN7 | septin 7 | -0.0238369 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0237726 |
| HLA-E | major histocompatibility complex, class I, E | -0.0235831 |
| CAVIN1 | caveolae associated protein 1 | -0.0235747 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0232317 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0230335 |
| CREBRF | CREB3 regulatory factor | -0.0229752 |
| ZNF721 | zinc finger protein 721 | -0.0226853 |
| RPL26 | ribosomal protein L26 | -0.0226744 |
| CFH | complement factor H | -0.0224512 |
| SERINC1 | serine incorporator 1 | -0.022414 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0222245 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0218086 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0217869 |
| ZFP91 | ZFP91 zinc finger protein | -0.0215809 |
| YBX3 | Y box binding protein 3 | -0.021575 |
| SMAD5 | SMAD family member 5 | -0.0214409 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0213236 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0212782 |
| NEMF | nuclear export mediator factor | -0.0212702 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | -0.0212521 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0212457 |
| ENOSF1 | enolase superfamily member 1 | -0.0210942 |
| CDK5RAP1 | CDK5 regulatory subunit associated protein 1 | -0.0210878 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0210295 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0209679 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.0209557 |
| FMN1 | formin 1 | -0.0207079 |
| ITGB4 | integrin, beta 4 | -0.0206084 |
| KIAA1549L | KIAA1549-like | -0.0203986 |
| PTS | 6-pyruvoyltetrahydropterin synthase | -0.0203878 |
| FAM3C | family with sequence similarity 3, member C | -0.0202515 |
| CD2AP | CD2-associated protein | -0.0202054 |
| CEP57 | centrosomal protein 57kDa | -0.0201899 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0200727 |
| NME7 | NME/NM23 family member 7 | -0.0198494 |
