Voriconazole Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description A triazole-based antifungal agent used for the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp. It is an inhibitor of cytochrome P450 2C9 (CYP2C9) and CYP3A4. (Chemical Entities of Biological Interest Ontology, CHEBI_10023)
External Link http://www.hmdb.ca/metabolites/HMDB14720
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Genes

8 interacting proteins for the Voriconazole metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
FMO1 flavin containing monooxygenase 1
FMO3 flavin containing monooxygenase 3
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)