| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FBN1 | fibrillin 1 | 0.15812 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.155112 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.147582 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.134106 |
| LOXL2 | lysyl oxidase-like 2 | 0.0930244 |
| COL1A2 | collagen, type I, alpha 2 | 0.0762504 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0714264 |
| COL3A1 | collagen, type III, alpha 1 | 0.0692741 |
| COL5A2 | collagen, type V, alpha 2 | 0.0676162 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0656815 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0655271 |
| LOX | lysyl oxidase | 0.0643574 |
| SBF2 | SET binding factor 2 | 0.0634174 |
| PLAT | plasminogen activator, tissue | 0.0591764 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.055474 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0554554 |
| FNDC3B | fibronectin type III domain containing 3B | 0.055033 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0542174 |
| CD44 | CD44 molecule (Indian blood group) | 0.0534763 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0533093 |
| ATP13A3 | ATPase type 13A3 | 0.0525254 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0478817 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0477557 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0470113 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0457507 |
| C1D | C1D nuclear receptor corepressor | 0.0425751 |
| OGA | O-GlcNAcase | 0.0421112 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0413164 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0402464 |
| GLIS3 | GLIS family zinc finger 3 | 0.0400154 |
| FLNB | filamin B, beta | 0.0383089 |
| MB21D2 | Mab-21 domain containing 2 | 0.0370911 |
| SFTPA2 | surfactant protein A2 | 0.036772 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.036418 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0360021 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0357839 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0356138 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0352395 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0350594 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0350586 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0344427 |
| FRMD5 | FERM domain containing 5 | 0.0342004 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.033805 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0337524 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0335438 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0323252 |
| SEPTIN9 | septin 9 | 0.0323048 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0323045 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.032035 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0319079 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0318276 |
| ARRDC3 | arrestin domain containing 3 | 0.0315893 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0315228 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0314599 |
| RUNX1 | runt-related transcription factor 1 | 0.0310055 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0306921 |
| GPC6 | glypican 6 | 0.0298717 |
| USP34 | ubiquitin specific peptidase 34 | 0.0296839 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0294468 |
| DST | dystonin | 0.0291481 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0288918 |
| KIFAP3 | kinesin-associated protein 3 | 0.0282382 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0281639 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0279817 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0276086 |
| AFDN | afadin, adherens junction formation factor | 0.0275009 |
| CTSB | cathepsin B | 0.0273863 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0273256 |
| YEATS2 | YEATS domain containing 2 | 0.0272589 |
| NGLY1 | N-glycanase 1 | 0.027213 |
| B2M | beta-2-microglobulin | 0.0268633 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0268309 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0267327 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.026731 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0266546 |
| RAI14 | retinoic acid induced 14 | 0.0264172 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0264165 |
| NKTR | natural killer cell triggering receptor | 0.0259893 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0258869 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0258782 |
| PFKP | phosphofructokinase, platelet | 0.025347 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0252878 |
| GOLGA4 | golgin A4 | 0.0250965 |
| ZNF148 | zinc finger protein 148 | 0.0249612 |
| APP | amyloid beta (A4) precursor protein | 0.0248787 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0246892 |
| ANK2 | ankyrin 2, neuronal | 0.0245705 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0245259 |
| FNIP1 | folliculin interacting protein 1 | 0.0244679 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0244225 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.024281 |
| COG5 | component of oligomeric golgi complex 5 | 0.0241688 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0240963 |
| TAOK1 | TAO kinase 1 | 0.0240545 |
| ACTN4 | actinin, alpha 4 | 0.0240262 |
| NAV1 | neuron navigator 1 | 0.0239267 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0238802 |
| CDK19 | cyclin-dependent kinase 19 | 0.0237865 |
| FAM219A | family with sequence similarity 219, member A | 0.0235431 |
| XPO1 | exportin 1 | 0.0235249 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.192931 |
| CDH13 | cadherin 13 | -0.133893 |
| AHNAK | AHNAK nucleoprotein | -0.0943859 |
| TMSB10 | thymosin beta 10 | -0.0877953 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0873806 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0777982 |
| CSTB | cystatin B (stefin B) | -0.0722832 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0704928 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0654323 |
| LMNA | lamin A/C | -0.0647324 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.064686 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0600943 |
| S100A10 | S100 calcium binding protein A10 | -0.0578246 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0559624 |
| VIM | vimentin | -0.0533915 |
| CANX | calnexin | -0.0530238 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0509549 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0505901 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0489063 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0460612 |
| RIGI | RNA sensor RIG-I | -0.0457492 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0438317 |
| CAVIN1 | caveolae associated protein 1 | -0.04036 |
| TMSB4X | thymosin beta 4, X-linked | -0.0401294 |
| ASPH | aspartate beta-hydroxylase | -0.0395753 |
| SQSTM1 | sequestosome 1 | -0.037785 |
| S100A6 | S100 calcium binding protein A6 | -0.03723 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0365754 |
| CCND1 | cyclin D1 | -0.0354013 |
| FN1 | fibronectin 1 | -0.0352366 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0349134 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0339472 |
| RPS24 | ribosomal protein S24 | -0.0339413 |
| MAP1B | microtubule-associated protein 1B | -0.0334472 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0329512 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0326241 |
| SP100 | SP100 nuclear antigen | -0.0322098 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0320991 |
| ADM | adrenomedullin | -0.0314194 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.031321 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.031058 |
| RPL23 | ribosomal protein L23 | -0.0294876 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0287724 |
| EFNA5 | ephrin-A5 | -0.0286152 |
| RND3 | Rho family GTPase 3 | -0.0285752 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0280884 |
| ANXA2 | annexin A2 | -0.0275684 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0275637 |
| SEC61G | Sec61 gamma subunit | -0.0272412 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0269961 |
| RPL26 | ribosomal protein L26 | -0.0266558 |
| PTMA | prothymosin, alpha | -0.0262829 |
| RPL35A | ribosomal protein L35a | -0.0262658 |
| MT2A | metallothionein 2A | -0.0261775 |
| FSTL1 | follistatin-like 1 | -0.0261342 |
| FTL | ferritin, light polypeptide | -0.025599 |
| ANKRD11 | ankyrin repeat domain 11 | -0.025147 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0250585 |
| LRRC17 | leucine rich repeat containing 17 | -0.0248429 |
| RPL34 | ribosomal protein L34 | -0.0246633 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0241824 |
| PLXNA2 | plexin A2 | -0.023961 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.023764 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.023739 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0236866 |
| ANXA1 | annexin A1 | -0.0233804 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0232922 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0232494 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0230992 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0225698 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0224327 |
| RPL12 | ribosomal protein L12 | -0.0220874 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0215938 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0213458 |
| LDHA | lactate dehydrogenase A | -0.0212919 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0212583 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.020922 |
| RPL37A | ribosomal protein L37a | -0.0206378 |
| HLA-C | major histocompatibility complex, class I, C | -0.0200305 |
| RPLP1 | ribosomal protein, large, P1 | -0.0199478 |
| RRBP1 | ribosome binding protein 1 | -0.0198944 |
| IL7R | interleukin 7 receptor | -0.0198033 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0193623 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.019361 |
| RPL37 | ribosomal protein L37 | -0.0193209 |
| INTS6 | integrator complex subunit 6 | -0.019183 |
| CUX1 | cut-like homeobox 1 | -0.0191758 |
| RACK1 | receptor for activated C kinase 1 | -0.0190592 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0189473 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0187373 |
| JUN | jun proto-oncogene | -0.0183115 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0180258 |
| PRSS23 | protease, serine, 23 | -0.0178395 |
| AEBP2 | AE binding protein 2 | -0.0177731 |
| CYTH3 | cytohesin 3 | -0.0177399 |
| RPS6 | ribosomal protein S6 | -0.0175139 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0175025 |
| EGFR | epidermal growth factor receptor | -0.0174917 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0171842 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0171247 |
