| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | 0.131259 |
| MMP12 | matrix metallopeptidase 12 | 0.084559 |
| TXNRD1 | thioredoxin reductase 1 | 0.0725079 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0632321 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0514004 |
| TENM3 | teneurin transmembrane protein 3 | 0.0506135 |
| WDR43 | WD repeat domain 43 | 0.0500983 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0499541 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0495106 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0483901 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0472783 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0466717 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0456632 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.045456 |
| NEK7 | NIMA-related kinase 7 | 0.0452814 |
| PDGFC | platelet derived growth factor C | 0.0448767 |
| ECT2 | epithelial cell transforming 2 | 0.0443288 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0436494 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0424618 |
| CCNL1 | cyclin L1 | 0.0419047 |
| OXR1 | oxidation resistance 1 | 0.0399964 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0388595 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0380083 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0377082 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0368761 |
| LMO7 | LIM domain 7 | 0.0365223 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.035038 |
| PCDH7 | protocadherin 7 | 0.035032 |
| ETNK1 | ethanolamine kinase 1 | 0.0349503 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0338739 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0334064 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0332722 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0327758 |
| RTN4 | reticulon 4 | 0.0321867 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0311645 |
| VCL | vinculin | 0.0304864 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.030295 |
| CCN2 | cellular communication network factor 2 | 0.0293597 |
| BCHE | butyrylcholinesterase | 0.0293452 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0291297 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0289939 |
| POTEF | POTE ankyrin domain family, member F | 0.0288229 |
| TMEM41B | transmembrane protein 41B | 0.0287355 |
| EXOC6B | exocyst complex component 6B | 0.028233 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0278057 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0277612 |
| XPO1 | exportin 1 | 0.0275718 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.027534 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0274173 |
| CLTC | clathrin, heavy chain (Hc) | 0.0266592 |
| MKI67 | marker of proliferation Ki-67 | 0.0264388 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0262239 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.025788 |
| ERBIN | erbb2 interacting protein | 0.0256979 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0255755 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0255412 |
| RNF13 | ring finger protein 13 | 0.0255199 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0254735 |
| SLC49A4 | solute carrier family 49 member 4 | 0.0253465 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0250412 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0249612 |
| NLN | neurolysin (metallopeptidase M3 family) | 0.0247078 |
| IPO7 | importin 7 | 0.0245666 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.024271 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0239402 |
| DST | dystonin | 0.023757 |
| CDCA2 | cell division cycle associated 2 | 0.0234398 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0232862 |
| CEP95 | centrosomal protein 95kDa | 0.0228881 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.022773 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0227453 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | 0.0226289 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0223648 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0223346 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0221318 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0219507 |
| PLK2 | polo-like kinase 2 | 0.0219103 |
| SBF2 | SET binding factor 2 | 0.0215323 |
| YAP1 | Yes-associated protein 1 | 0.0213398 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0211796 |
| SACS | sacsin molecular chaperone | 0.0210872 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0207343 |
| NUP153 | nucleoporin 153kDa | 0.0206309 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0206169 |
| TJP1 | tight junction protein 1 | 0.0205228 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0203661 |
| MPG | N-methylpurine-DNA glycosylase | 0.0202883 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0200706 |
| EDN1 | endothelin 1 | 0.0200558 |
| TCERG1 | transcription elongation regulator 1 | 0.0200312 |
| ETV5 | ets variant 5 | 0.0199895 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.019879 |
| KLHL24 | kelch-like family member 24 | 0.0198699 |
| TMEM123 | transmembrane protein 123 | 0.0198276 |
| SP3 | Sp3 transcription factor | 0.0198228 |
| TMEM131 | transmembrane protein 131 | 0.0197393 |
| CEP70 | centrosomal protein 70kDa | 0.0197186 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0196377 |
| ATL2 | atlastin GTPase 2 | 0.019503 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0194098 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0986537 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.08839 |
| VIM | vimentin | -0.0814411 |
| HMGA2 | high mobility group AT-hook 2 | -0.0727371 |
| PTMA | prothymosin, alpha | -0.0720291 |
| TMSB10 | thymosin beta 10 | -0.0642132 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0578838 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0561704 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0548415 |
| FTL | ferritin, light polypeptide | -0.0518699 |
| INTS6 | integrator complex subunit 6 | -0.0489166 |
| RPS8 | ribosomal protein S8 | -0.0486573 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0480458 |
| LRRC23 | leucine rich repeat containing 23 | -0.046455 |
| NHSL1 | NHS-like 1 | -0.0463244 |
| GNAS | GNAS complex locus | -0.0453115 |
| RPL35A | ribosomal protein L35a | -0.0448704 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0420486 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0417751 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0408548 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0392233 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0366844 |
| CUX1 | cut-like homeobox 1 | -0.0356878 |
| RPL19 | ribosomal protein L19 | -0.035613 |
| RPL23 | ribosomal protein L23 | -0.035607 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0354179 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0334226 |
| ASPH | aspartate beta-hydroxylase | -0.0333326 |
| S100A6 | S100 calcium binding protein A6 | -0.0318458 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0318114 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0317828 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0309153 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0308767 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0308428 |
| RPL34 | ribosomal protein L34 | -0.0306056 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0297536 |
| RPS3 | ribosomal protein S3 | -0.0296628 |
| AHNAK | AHNAK nucleoprotein | -0.0295136 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0288775 |
| RBM39 | RNA binding motif protein 39 | -0.0288526 |
| DENND5A | DENN/MADD domain containing 5A | -0.0286807 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0281055 |
| TPM4 | tropomyosin 4 | -0.028068 |
| RPL37A | ribosomal protein L37a | -0.0277482 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0272951 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0263088 |
| BCL6 | B-cell CLL/lymphoma 6 | -0.0259844 |
| RLF | rearranged L-myc fusion | -0.0257181 |
| ADIPOR2 | adiponectin receptor 2 | -0.0255679 |
| RPL36 | ribosomal protein L36 | -0.0250471 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.025016 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0248454 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0247272 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0245067 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0243365 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0243196 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0239254 |
| RPS12 | ribosomal protein S12 | -0.0238975 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0237657 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0237355 |
| TFRC | transferrin receptor | -0.0237193 |
| AREG | amphiregulin | -0.0236288 |
| SQSTM1 | sequestosome 1 | -0.0233805 |
| YBX3 | Y box binding protein 3 | -0.0232929 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0231585 |
| DENND1A | DENN/MADD domain containing 1A | -0.0230088 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.0225605 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0224369 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0223689 |
| RPL12 | ribosomal protein L12 | -0.0222468 |
| MORF4L2 | mortality factor 4 like 2 | -0.0221852 |
| CALR | calreticulin | -0.0221022 |
| EHBP1 | EH domain binding protein 1 | -0.02208 |
| TPI1 | triosephosphate isomerase 1 | -0.0220516 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0219007 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0216523 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0215168 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.021493 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0214619 |
| ANXA2 | annexin A2 | -0.0214131 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0213575 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0208652 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0207939 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0207907 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0206851 |
| GOLGA4 | golgin A4 | -0.0205499 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0204377 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0202847 |
| RPL37 | ribosomal protein L37 | -0.0202296 |
| S100A10 | S100 calcium binding protein A10 | -0.0201755 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0201234 |
| CANX | calnexin | -0.0197349 |
| RPLP1 | ribosomal protein, large, P1 | -0.0197315 |
| RPL31 | ribosomal protein L31 | -0.0195376 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0194871 |
| RAB7A | RAB7A, member RAS oncogene family | -0.019485 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0192158 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0191605 |
| RPS25 | ribosomal protein S25 | -0.0190913 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0190851 |
