| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.339456 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.175948 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0867686 |
| COL3A1 | collagen, type III, alpha 1 | 0.0826666 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.079303 |
| TOP1 | topoisomerase (DNA) I | 0.0570125 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0506638 |
| MYO6 | myosin VI | 0.0502718 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0494071 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0442869 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0439557 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0431687 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0416453 |
| PLAT | plasminogen activator, tissue | 0.0415167 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0412407 |
| HDLBP | high density lipoprotein binding protein | 0.0408957 |
| VCL | vinculin | 0.0401791 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0365984 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0359766 |
| VIM | vimentin | 0.0345834 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0344695 |
| ANXA2 | annexin A2 | 0.0341467 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0339461 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0336087 |
| MMP2 | matrix metallopeptidase 2 | 0.031551 |
| PTK2 | protein tyrosine kinase 2 | 0.0312167 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0307079 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.030343 |
| POTEF | POTE ankyrin domain family, member F | 0.0302335 |
| NCKAP1 | NCK-associated protein 1 | 0.02969 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0296133 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.028825 |
| PKM | pyruvate kinase, muscle | 0.028522 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0282097 |
| UBAP2L | ubiquitin associated protein 2-like | 0.027485 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0274338 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0273298 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0272626 |
| GPC5 | glypican 5 | 0.0270493 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.026735 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0265675 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0265181 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0264107 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0257407 |
| COPA | coatomer protein complex, subunit alpha | 0.0257198 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.025694 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0256319 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0254081 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0252909 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.0246815 |
| UBC | ubiquitin C | 0.0245089 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0245074 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0243863 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0242621 |
| ENO1 | enolase 1, (alpha) | 0.0237111 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0235468 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0234972 |
| RNF20 | ring finger protein 20, E3 ubiquitin protein ligase | 0.0234812 |
| PGK1 | phosphoglycerate kinase 1 | 0.023457 |
| MSI2 | musashi RNA-binding protein 2 | 0.023118 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0230645 |
| ATXN2 | ataxin 2 | 0.0227703 |
| PCNX1 | pecanex 1 | 0.0227089 |
| MATR3 | matrin 3 | 0.0226675 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0226435 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0225631 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0223873 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0223401 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.022282 |
| CANX | calnexin | 0.0222805 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0222767 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0222375 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0221618 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0220919 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0220474 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0217205 |
| RYK | receptor-like tyrosine kinase | 0.0216123 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0215437 |
| YAP1 | Yes-associated protein 1 | 0.0210979 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0210481 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0210053 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0209791 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0209685 |
| MAP4 | microtubule-associated protein 4 | 0.0208569 |
| CALR | calreticulin | 0.0207585 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) | 0.0206827 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0206723 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0206277 |
| CALU | calumenin | 0.0203674 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0203337 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0203082 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0203078 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0202341 |
| VMP1 | vacuole membrane protein 1 | 0.0201526 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.020115 |
| RNF10 | ring finger protein 10 | 0.0200677 |
| PTEN | phosphatase and tensin homolog | 0.0199689 |
| GDF15 | growth differentiation factor 15 | 0.0198645 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0197443 |
| CEP85L | centrosomal protein 85kDa-like | 0.0197349 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.104 |
| FMN1 | formin 1 | -0.0861235 |
| RPS6 | ribosomal protein S6 | -0.0778636 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0756416 |
| RPL38 | ribosomal protein L38 | -0.0645865 |
| SYT1 | synaptotagmin I | -0.05497 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0521056 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0474197 |
| RPS2 | ribosomal protein S2 | -0.045611 |
| FNBP1 | formin binding protein 1 | -0.0454044 |
| MEIS2 | Meis homeobox 2 | -0.0449205 |
| BPTF | bromodomain PHD finger transcription factor | -0.0447579 |
| RPL7 | ribosomal protein L7 | -0.0442439 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0425552 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0423698 |
| SP100 | SP100 nuclear antigen | -0.0421149 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0389648 |
| CENPF | centromere protein F, 350/400kDa | -0.038348 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0373755 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0362778 |
| LSAMP | limbic system-associated membrane protein | -0.0347218 |
| RIGI | RNA sensor RIG-I | -0.0344175 |
| SMYD3 | SET and MYND domain containing 3 | -0.0325404 |
| RPL23 | ribosomal protein L23 | -0.0323393 |
| MEF2A | myocyte enhancer factor 2A | -0.0322318 |
| RPS19 | ribosomal protein S19 | -0.0318934 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0318419 |
| INTU | inturned planar cell polarity protein | -0.0308798 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0306215 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0303817 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0298022 |
| RPL35A | ribosomal protein L35a | -0.0292702 |
| DPH6 | diphthamine biosynthesis 6 | -0.02837 |
| PHF21A | PHD finger protein 21A | -0.0278858 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0278322 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.027799 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0276735 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0275238 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0273229 |
| ZFHX3 | zinc finger homeobox 3 | -0.0272885 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0270741 |
| SQSTM1 | sequestosome 1 | -0.0269343 |
| KIAA1217 | KIAA1217 | -0.0267074 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0266008 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0264783 |
| ADAR | adenosine deaminase, RNA-specific | -0.0262952 |
| NKTR | natural killer cell triggering receptor | -0.026093 |
| RPLP1 | ribosomal protein, large, P1 | -0.0255364 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0255358 |
| ERBIN | erbb2 interacting protein | -0.0254725 |
| CEP350 | centrosomal protein 350kDa | -0.0253739 |
| CADM1 | cell adhesion molecule 1 | -0.0250801 |
| HDGF | hepatoma-derived growth factor | -0.0250544 |
| RPS11 | ribosomal protein S11 | -0.0250166 |
| TPR | translocated promoter region, nuclear basket protein | -0.0248532 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0248326 |
| TP53 | tumor protein p53 | -0.0247363 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0245607 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0245521 |
| ACTG1 | actin gamma 1 | -0.0244875 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0244414 |
| RPS12 | ribosomal protein S12 | -0.0243978 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0239623 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0236992 |
| CENPE | centromere protein E, 312kDa | -0.023605 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0235984 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0233556 |
| RBM20 | RNA binding motif protein 20 | -0.023343 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0233108 |
| RTN4 | reticulon 4 | -0.0232419 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0231735 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.02306 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0228111 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0226605 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0226357 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0223756 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.022134 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0220243 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0219206 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0217556 |
| DNMBP | dynamin binding protein | -0.0216022 |
| PTMA | prothymosin, alpha | -0.0214309 |
| RPS25 | ribosomal protein S25 | -0.0207352 |
| NRG1 | neuregulin 1 | -0.0206953 |
| ZNF638 | zinc finger protein 638 | -0.0206711 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0205737 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.020549 |
| SUCO | SUN domain containing ossification factor | -0.0203474 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0202538 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0202186 |
| MORF4L2 | mortality factor 4 like 2 | -0.0201354 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0199704 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.019864 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0198163 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0197716 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0197348 |
| CDC73 | cell division cycle 73 | -0.0196832 |
| RPL37 | ribosomal protein L37 | -0.0196445 |
| NBEA | neurobeachin | -0.0196394 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0194683 |
