| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.177308 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0384609 |
| ATP13A3 | ATPase type 13A3 | 0.0347618 |
| SMAD3 | SMAD family member 3 | 0.0313296 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0308155 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0286362 |
| POSTN | periostin, osteoblast specific factor | 0.0280355 |
| HMGA2 | high mobility group AT-hook 2 | 0.0250458 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0241522 |
| RASA2 | RAS p21 protein activator 2 | 0.023503 |
| NAV2 | neuron navigator 2 | 0.0225737 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0218202 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0215871 |
| ARRDC3 | arrestin domain containing 3 | 0.0215462 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0192401 |
| VEGFA | vascular endothelial growth factor A | 0.0186633 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.017824 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0177696 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0176296 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.016214 |
| AXL | AXL receptor tyrosine kinase | 0.0161332 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0159249 |
| LOX | lysyl oxidase | 0.0151039 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0149858 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0149717 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0147467 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0147388 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0147043 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0146009 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0142227 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0140328 |
| MTSS1 | metastasis suppressor 1 | 0.0140019 |
| SBF2 | SET binding factor 2 | 0.0138051 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0135844 |
| ECE1 | endothelin converting enzyme 1 | 0.0135524 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0134403 |
| MSN | moesin | 0.0131926 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0129748 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0129163 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0126345 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0124615 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0123414 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0122042 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0122033 |
| CENPF | centromere protein F, 350/400kDa | 0.0121527 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0121481 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0120526 |
| HAS2 | hyaluronan synthase 2 | 0.0117822 |
| CD44 | CD44 molecule (Indian blood group) | 0.0116745 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0112159 |
| MKI67 | marker of proliferation Ki-67 | 0.0111713 |
| ANXA5 | annexin A5 | 0.0111381 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0108521 |
| SQLE | squalene epoxidase | 0.0107527 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0107475 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0106885 |
| NUP58 | nucleoporin 58 | 0.0106697 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0106638 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0104326 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0103429 |
| SPAG9 | sperm associated antigen 9 | 0.0103288 |
| VMP1 | vacuole membrane protein 1 | 0.0102762 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0102732 |
| ANO6 | anoctamin 6 | 0.00999985 |
| MLF1 | myeloid leukemia factor 1 | 0.00989578 |
| ZNF292 | zinc finger protein 292 | 0.00989018 |
| ECT2 | epithelial cell transforming 2 | 0.0098803 |
| PHIP | pleckstrin homology domain interacting protein | 0.00979648 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.00976623 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00971925 |
| SERINC3 | serine incorporator 3 | 0.00962116 |
| USP47 | ubiquitin specific peptidase 47 | 0.00961286 |
| DIAPH3 | diaphanous-related formin 3 | 0.00956625 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00945027 |
| ZNF148 | zinc finger protein 148 | 0.00942743 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.00937478 |
| FOSL1 | FOS-like antigen 1 | 0.00931845 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.00930552 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.00928838 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00926521 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.00923797 |
| ERBIN | erbb2 interacting protein | 0.009191 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0091707 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.00915646 |
| SLC35F5 | solute carrier family 35, member F5 | 0.00913844 |
| FAT1 | FAT atypical cadherin 1 | 0.00910028 |
| ACTN4 | actinin, alpha 4 | 0.00909516 |
| RNF145 | ring finger protein 145 | 0.00908291 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.00905237 |
| AZIN1 | antizyme inhibitor 1 | 0.00901742 |
| HIPK1 | homeodomain interacting protein kinase 1 | 0.00897933 |
| GOLGA4 | golgin A4 | 0.00893508 |
| ANLN | anillin, actin binding protein | 0.00887845 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.00882452 |
| GPSM2 | G-protein signaling modulator 2 | 0.00882441 |
| IKZF2 | IKAROS family zinc finger 2 (Helios) | 0.00880834 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.00877164 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.00876945 |
| TPX2 | TPX2, microtubule-associated | 0.00859639 |
| SLMAP | sarcolemma associated protein | 0.00849943 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.182335 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.170703 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.13817 |
| CDH13 | cadherin 13 | -0.117266 |
| VIM | vimentin | -0.0942669 |
| NDRG1 | N-myc downstream regulated 1 | -0.0856483 |
| COL1A1 | collagen, type I, alpha 1 | -0.0775184 |
| TMSB10 | thymosin beta 10 | -0.0585504 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0542772 |
| IER3 | immediate early response 3 | -0.0536265 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0525284 |
| RPS8 | ribosomal protein S8 | -0.0522197 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.052133 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0487698 |
| RPL35A | ribosomal protein L35a | -0.0483435 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0464326 |
| RPS6 | ribosomal protein S6 | -0.0452927 |
| AHNAK | AHNAK nucleoprotein | -0.0422196 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0419792 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0412902 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0390492 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0384926 |
| MT2A | metallothionein 2A | -0.0370216 |
| CADM1 | cell adhesion molecule 1 | -0.0363503 |
| FBN1 | fibrillin 1 | -0.0360336 |
| CANX | calnexin | -0.0357241 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0353949 |
| PTMA | prothymosin, alpha | -0.0338042 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0335409 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0326179 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0321907 |
| HLA-B | major histocompatibility complex, class I, B | -0.0319063 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0316985 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0305701 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0303541 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0301264 |
| SQSTM1 | sequestosome 1 | -0.0299774 |
| ASPH | aspartate beta-hydroxylase | -0.0297283 |
| RPL26 | ribosomal protein L26 | -0.0292363 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0287025 |
| ENO1 | enolase 1, (alpha) | -0.0282626 |
| RPL23 | ribosomal protein L23 | -0.0277373 |
| FTL | ferritin, light polypeptide | -0.0273563 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0272429 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0267588 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0266686 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0259828 |
| MTDH | metadherin | -0.0257677 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.025743 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0254143 |
| GOLGB1 | golgin B1 | -0.0250103 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0250018 |
| TPM4 | tropomyosin 4 | -0.0247917 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0247747 |
| ACTG1 | actin gamma 1 | -0.0246711 |
| RPL30 | ribosomal protein L30 | -0.0246599 |
| GLIS3 | GLIS family zinc finger 3 | -0.0243598 |
| RPL34 | ribosomal protein L34 | -0.0239512 |
| COL1A2 | collagen, type I, alpha 2 | -0.0239429 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0235775 |
| RPS3 | ribosomal protein S3 | -0.0233252 |
| RPL12 | ribosomal protein L12 | -0.0232191 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0232092 |
| RPL37A | ribosomal protein L37a | -0.0230828 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0230546 |
| RRBP1 | ribosome binding protein 1 | -0.0227908 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0225754 |
| RPLP1 | ribosomal protein, large, P1 | -0.0223509 |
| COL5A1 | collagen, type V, alpha 1 | -0.0223312 |
| SP100 | SP100 nuclear antigen | -0.0219824 |
| RPL11 | ribosomal protein L11 | -0.0218346 |
| RPS20 | ribosomal protein S20 | -0.021797 |
| S100A9 | S100 calcium binding protein A9 | -0.0212223 |
| RPL19 | ribosomal protein L19 | -0.0208922 |
| RPS12 | ribosomal protein S12 | -0.0208729 |
| RPL28 | ribosomal protein L28 | -0.0207462 |
| CALR | calreticulin | -0.0205229 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0204342 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0202835 |
| TMSB4X | thymosin beta 4, X-linked | -0.0200855 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0200312 |
| RPL5 | ribosomal protein L5 | -0.0198749 |
| NEK10 | NIMA-related kinase 10 | -0.0198369 |
| RPS19 | ribosomal protein S19 | -0.0196978 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0196598 |
| MAP4 | microtubule-associated protein 4 | -0.0193158 |
| RACK1 | receptor for activated C kinase 1 | -0.0192852 |
| RPS25 | ribosomal protein S25 | -0.019223 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0190979 |
| IL6ST | interleukin 6 signal transducer | -0.0190581 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0188607 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.018788 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0184932 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0182075 |
| RPL36 | ribosomal protein L36 | -0.0181409 |
| CNTN5 | contactin 5 | -0.0181165 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0180541 |
| CUX1 | cut-like homeobox 1 | -0.0180001 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0179914 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0175696 |
