| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.299955 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.2338 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.18225 |
| C3 | complement component 3 | 0.109826 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0952824 |
| APOB | apolipoprotein B | 0.0787764 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0568945 |
| FN1 | fibronectin 1 | 0.0536356 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0511605 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0458069 |
| FAT1 | FAT atypical cadherin 1 | 0.0403573 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0364266 |
| SVIL | supervillin | 0.0360625 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0354478 |
| VMP1 | vacuole membrane protein 1 | 0.0327156 |
| VCL | vinculin | 0.0321453 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0312929 |
| ITGAV | integrin, alpha V | 0.031134 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0291024 |
| JAG1 | jagged 1 | 0.0278809 |
| SKIL | SKI-like proto-oncogene | 0.0277432 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0276901 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0269499 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0260914 |
| MATR3 | matrin 3 | 0.025818 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.025722 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0252046 |
| SMAD3 | SMAD family member 3 | 0.0251078 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0247039 |
| ZNF644 | zinc finger protein 644 | 0.0246413 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0243771 |
| HLF | hepatic leukemia factor | 0.0242952 |
| MKI67 | marker of proliferation Ki-67 | 0.0241278 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0236061 |
| FNIP1 | folliculin interacting protein 1 | 0.0231819 |
| RTN4 | reticulon 4 | 0.0228927 |
| SORT1 | sortilin 1 | 0.0227261 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0223474 |
| PRELID2 | PRELI domain containing 2 | 0.022228 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0222256 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0218438 |
| CENPF | centromere protein F, 350/400kDa | 0.0215744 |
| MRTFA | myocardin related transcription factor A | 0.0215664 |
| FERMT2 | fermitin family member 2 | 0.0214275 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0212928 |
| ANXA5 | annexin A5 | 0.021134 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0211326 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0210144 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0207962 |
| NCKAP1 | NCK-associated protein 1 | 0.0206844 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0206195 |
| POTEF | POTE ankyrin domain family, member F | 0.0204266 |
| MED13L | mediator complex subunit 13-like | 0.0203032 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0202707 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0200902 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0199479 |
| ITGB5 | integrin, beta 5 | 0.0198373 |
| DENND5A | DENN/MADD domain containing 5A | 0.0198282 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0195524 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.019529 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.019476 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0192951 |
| CUL3 | cullin 3 | 0.0191293 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.019007 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0186479 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0186285 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0184875 |
| ENAH | enabled homolog (Drosophila) | 0.0184253 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.018226 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0181783 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0181269 |
| PTK2 | protein tyrosine kinase 2 | 0.0181014 |
| ACTN4 | actinin, alpha 4 | 0.0178399 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0176721 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0176567 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0176199 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0174543 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0174362 |
| CENPE | centromere protein E, 312kDa | 0.0173394 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0172756 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.017245 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0170824 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0167517 |
| DNMBP | dynamin binding protein | 0.0164609 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0163354 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.0162447 |
| ARRDC3 | arrestin domain containing 3 | 0.0161115 |
| PHF3 | PHD finger protein 3 | 0.0161101 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.015984 |
| VEGFA | vascular endothelial growth factor A | 0.0159386 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0159381 |
| ZFP36 | ZFP36 ring finger protein | 0.0157491 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0155692 |
| BCL2L1 | BCL2-like 1 | 0.0153863 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0152093 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0151803 |
| FZD6 | frizzled class receptor 6 | 0.0151646 |
| FILIP1L | filamin A interacting protein 1-like | 0.0150723 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0150473 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0149531 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.170743 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0849772 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0790112 |
| EHBP1 | EH domain binding protein 1 | -0.0780208 |
| GPC3 | glypican 3 | -0.0705994 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0687282 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0669963 |
| CP | ceruloplasmin (ferroxidase) | -0.0662467 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0659548 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0593834 |
| RPS6 | ribosomal protein S6 | -0.0553894 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.055323 |
| APOA2 | apolipoprotein A-II | -0.0547124 |
| NPR2 | natriuretic peptide receptor 2 | -0.0537301 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0529822 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0517795 |
| GPC6 | glypican 6 | -0.0510999 |
| MT2A | metallothionein 2A | -0.0505188 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0473034 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.045863 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0454321 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0420931 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0417796 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0410403 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0398829 |
| RPS24 | ribosomal protein S24 | -0.0396138 |
| GNAS | GNAS complex locus | -0.0394282 |
| TMSB10 | thymosin beta 10 | -0.0394044 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0390098 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0390094 |
| RPL12 | ribosomal protein L12 | -0.0387089 |
| FMNL2 | formin-like 2 | -0.0377756 |
| TF | transferrin | -0.0368444 |
| AHSG | alpha-2-HS-glycoprotein | -0.0359629 |
| RRBP1 | ribosome binding protein 1 | -0.0354764 |
| RPL11 | ribosomal protein L11 | -0.03475 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0339029 |
| CALR | calreticulin | -0.0338423 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.033387 |
| FRMD5 | FERM domain containing 5 | -0.0326043 |
| RPL31 | ribosomal protein L31 | -0.0323543 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0317747 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.031495 |
| ENO1 | enolase 1, (alpha) | -0.0309257 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0308539 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0308293 |
| FTL | ferritin, light polypeptide | -0.0303311 |
| TMEM123 | transmembrane protein 123 | -0.0299874 |
| RBM39 | RNA binding motif protein 39 | -0.0298896 |
| H1-0 | H1.0 linker histone | -0.0297586 |
| WDR45B | WD repeat domain 45B | -0.0297127 |
| RPL34 | ribosomal protein L34 | -0.0294334 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0293909 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0293411 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0291265 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0290684 |
| RPS8 | ribosomal protein S8 | -0.0289574 |
| RPS27A | ribosomal protein S27a | -0.0286157 |
| RPL23 | ribosomal protein L23 | -0.0286051 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0280195 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0279633 |
| NHSL1 | NHS-like 1 | -0.0275337 |
| ZFHX3 | zinc finger homeobox 3 | -0.027469 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0272345 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0269458 |
| RPL38 | ribosomal protein L38 | -0.0268859 |
| RPS29 | ribosomal protein S29 | -0.026483 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.026336 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0260888 |
| PTMA | prothymosin, alpha | -0.0260789 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0257399 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.025687 |
| APOA1 | apolipoprotein A-I | -0.0250849 |
| CPE | carboxypeptidase E | -0.0250639 |
| STK17A | serine/threonine kinase 17a | -0.0246771 |
| RPLP2 | ribosomal protein, large, P2 | -0.0244642 |
| NDRG1 | N-myc downstream regulated 1 | -0.0244332 |
| TPM4 | tropomyosin 4 | -0.024369 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0243557 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0242073 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0238873 |
| FAM13A | family with sequence similarity 13, member A | -0.0238678 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0238215 |
| RNF213 | ring finger protein 213 | -0.0238191 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0236594 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0229554 |
| HM13 | histocompatibility (minor) 13 | -0.0226258 |
| IER3 | immediate early response 3 | -0.022239 |
| CANX | calnexin | -0.0222205 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0221844 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0221733 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0218759 |
| CALD1 | caldesmon 1 | -0.0218099 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0217802 |
| RNASET2 | ribonuclease T2 | -0.0214967 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0214205 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0212294 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0211925 |
| RPS13 | ribosomal protein S13 | -0.0211919 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0211716 |
