| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.150612 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0595567 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.053385 |
| POTEF | POTE ankyrin domain family, member F | 0.0470831 |
| AREG | amphiregulin | 0.0466922 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0454205 |
| MYO1E | myosin IE | 0.0435041 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.036742 |
| RNF145 | ring finger protein 145 | 0.0364955 |
| VEGFA | vascular endothelial growth factor A | 0.0345168 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0310072 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0305562 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.029504 |
| PCBP2 | poly(rC) binding protein 2 | 0.0293831 |
| VMP1 | vacuole membrane protein 1 | 0.028233 |
| RPL3 | ribosomal protein L3 | 0.027123 |
| RCOR1 | REST corepressor 1 | 0.0263927 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0253606 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0250971 |
| LMO7 | LIM domain 7 | 0.0242465 |
| CALB1 | calbindin 1, 28kDa | 0.0227685 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0227471 |
| ABHD2 | abhydrolase domain containing 2 | 0.0225022 |
| ASPH | aspartate beta-hydroxylase | 0.0219688 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0219528 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0214198 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0209323 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0208116 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0208042 |
| SLK | STE20-like kinase | 0.019434 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0188047 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.018796 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0186357 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0179888 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0172063 |
| EGR1 | early growth response 1 | 0.0166507 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0165206 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0164774 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0163931 |
| DIAPH1 | diaphanous-related formin 1 | 0.0163743 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0162924 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0161717 |
| SETD5 | SET domain containing 5 | 0.0158892 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0156423 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.0152801 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0152636 |
| PNN | pinin, desmosome associated protein | 0.0152459 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0152393 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0152042 |
| RPL21 | ribosomal protein L21 | 0.0151247 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.015078 |
| CCNL1 | cyclin L1 | 0.0150744 |
| NUP58 | nucleoporin 58 | 0.0148374 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0148349 |
| FAT1 | FAT atypical cadherin 1 | 0.0147792 |
| BRD2 | bromodomain containing 2 | 0.0146128 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0144846 |
| ZNF451 | zinc finger protein 451 | 0.0143011 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0142121 |
| CLDN4 | claudin 4 | 0.0140621 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0140611 |
| LAMA4 | laminin, alpha 4 | 0.0139041 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0138145 |
| TFF1 | trefoil factor 1 | 0.0136455 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0136352 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0134857 |
| SVIL | supervillin | 0.0134834 |
| PFN1 | profilin 1 | 0.0134002 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0133224 |
| PKP2 | plakophilin 2 | 0.0133205 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | 0.0132846 |
| SNX9 | sorting nexin 9 | 0.0130983 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0129879 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0128746 |
| TMF1 | TATA element modulatory factor 1 | 0.0128376 |
| PAPOLA | poly(A) polymerase alpha | 0.0127109 |
| SRP54 | signal recognition particle 54kDa | 0.0126162 |
| YTHDC1 | YTH domain containing 1 | 0.0125895 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0125366 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0122542 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0121444 |
| PLS1 | plastin 1 | 0.0121143 |
| CCNC | cyclin C | 0.012061 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0119811 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0118401 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0118121 |
| YBX1 | Y box binding protein 1 | 0.0118111 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0117256 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0116366 |
| LIN7C | lin-7 homolog C (C. elegans) | 0.0116235 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0115998 |
| NOSTRIN | nitric oxide synthase trafficking | 0.0115844 |
| PGM3 | phosphoglucomutase 3 | 0.0115203 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0114756 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0113935 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.011357 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0112879 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0111674 |
| TPM3 | tropomyosin 3 | 0.0110932 |
| LIPH | lipase, member H | 0.0110618 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.280652 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.19985 |
| PTMA | prothymosin, alpha | -0.126725 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.122042 |
| AHNAK | AHNAK nucleoprotein | -0.115997 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.1093 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0855341 |
| NDRG1 | N-myc downstream regulated 1 | -0.0814747 |
| H1-0 | H1.0 linker histone | -0.0777683 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0746851 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0739618 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0723947 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0688015 |
| NPSR1 | neuropeptide S receptor 1 | -0.0678714 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.065958 |
| ONECUT3 | one cut homeobox 3 | -0.0616315 |
| PRELID2 | PRELI domain containing 2 | -0.0550219 |
| RNF43 | ring finger protein 43 | -0.0537353 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0535943 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0533838 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0523882 |
| EZR | ezrin | -0.0521874 |
| RPS24 | ribosomal protein S24 | -0.0521328 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0482128 |
| ANXA2 | annexin A2 | -0.0462203 |
| RRBP1 | ribosome binding protein 1 | -0.0453405 |
| AGR2 | anterior gradient 2 | -0.044636 |
| TMSB10 | thymosin beta 10 | -0.0441308 |
| CD44 | CD44 molecule (Indian blood group) | -0.0418683 |
| CANX | calnexin | -0.041679 |
| ACTN4 | actinin, alpha 4 | -0.0413223 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0399709 |
| RPLP1 | ribosomal protein, large, P1 | -0.0390034 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0377501 |
| OGA | O-GlcNAcase | -0.036837 |
| RPL34 | ribosomal protein L34 | -0.0365404 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0362468 |
| NFIA | nuclear factor I/A | -0.0355694 |
| ATXN1 | ataxin 1 | -0.0355249 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0353281 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0352908 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0352268 |
| FHIT | fragile histidine triad | -0.0351517 |
| PGK1 | phosphoglycerate kinase 1 | -0.0344433 |
| FAM13A | family with sequence similarity 13, member A | -0.034065 |
| CALR | calreticulin | -0.0339722 |
| RPL26 | ribosomal protein L26 | -0.0339694 |
| GPHN | gephyrin | -0.0338833 |
| S100A10 | S100 calcium binding protein A10 | -0.0334073 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0333542 |
| NEBL | nebulette | -0.0327863 |
| PCDHB16 | protocadherin beta 16 | -0.0326581 |
| CADPS | Ca++-dependent secretion activator | -0.0323924 |
| RPS8 | ribosomal protein S8 | -0.0322259 |
| SERINC5 | serine incorporator 5 | -0.0319958 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0315535 |
| RPS6 | ribosomal protein S6 | -0.0311645 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0305442 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0304095 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0303576 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0296979 |
| TFRC | transferrin receptor | -0.0296852 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0295412 |
| FOXP1 | forkhead box P1 | -0.0294831 |
| RPL23 | ribosomal protein L23 | -0.0289777 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0288382 |
| RPS19 | ribosomal protein S19 | -0.0287938 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0287482 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0286676 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0284839 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0283331 |
| SMYD3 | SET and MYND domain containing 3 | -0.0278666 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.027654 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0274057 |
| RPL38 | ribosomal protein L38 | -0.027359 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0271579 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0270968 |
| HDLBP | high density lipoprotein binding protein | -0.0270087 |
| PRSS3 | protease, serine, 3 | -0.0267458 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0264171 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0263268 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0258356 |
| TMSB4X | thymosin beta 4, X-linked | -0.0258155 |
| ARF1 | ADP-ribosylation factor 1 | -0.0257706 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0257654 |
| DSG2 | desmoglein 2 | -0.0257219 |
| ZNF292 | zinc finger protein 292 | -0.025698 |
| RPL30 | ribosomal protein L30 | -0.0255958 |
| ADD3 | adducin 3 (gamma) | -0.0254266 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0254121 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0253588 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0252388 |
| DEK | DEK proto-oncogene | -0.0250992 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0250165 |
| HMGB1 | high mobility group box 1 | -0.0249614 |
| INSIG1 | insulin induced gene 1 | -0.024876 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0246429 |
| SBF2 | SET binding factor 2 | -0.0245365 |
| RPL9 | ribosomal protein L9 | -0.0243303 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0241139 |
