| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.105943 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.102802 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0986855 |
| MCL1 | myeloid cell leukemia 1 | 0.0779926 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0749547 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.071693 |
| EGR1 | early growth response 1 | 0.0629252 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0585122 |
| LMO7 | LIM domain 7 | 0.0474866 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0471651 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0462166 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0419091 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0403692 |
| CAV2 | caveolin 2 | 0.0376838 |
| MSN | moesin | 0.0376792 |
| CST3 | cystatin C | 0.0373942 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0358258 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0356918 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0351492 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0343254 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0342331 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0333538 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0313341 |
| CPE | carboxypeptidase E | 0.0312176 |
| AREG | amphiregulin | 0.0310934 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0305355 |
| POTEF | POTE ankyrin domain family, member F | 0.0302667 |
| VMP1 | vacuole membrane protein 1 | 0.0279277 |
| ACTG1 | actin gamma 1 | 0.0274918 |
| SCEL | sciellin | 0.0272271 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.026789 |
| ANXA5 | annexin A5 | 0.0254909 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0254334 |
| MYO1D | myosin ID | 0.0252927 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0243911 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0237473 |
| TPM4 | tropomyosin 4 | 0.0236755 |
| FTL | ferritin, light polypeptide | 0.0236715 |
| PTEN | phosphatase and tensin homolog | 0.0232946 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0232187 |
| LAMC2 | laminin, gamma 2 | 0.0231629 |
| TMSB10 | thymosin beta 10 | 0.0231442 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0231211 |
| PKM | pyruvate kinase, muscle | 0.0223924 |
| PCBP2 | poly(rC) binding protein 2 | 0.0223167 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0215232 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0212798 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0212234 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0212136 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0206132 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0204042 |
| SLK | STE20-like kinase | 0.020402 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0203642 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0203585 |
| PTK2 | protein tyrosine kinase 2 | 0.0203476 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0203195 |
| OXSR1 | oxidative stress responsive 1 | 0.0202676 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0201154 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0199743 |
| CCNL1 | cyclin L1 | 0.0198893 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0193625 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0192339 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0190467 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0190143 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0189182 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0187846 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0185477 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0184487 |
| ATP11A | ATPase, class VI, type 11A | 0.0184414 |
| DIAPH1 | diaphanous-related formin 1 | 0.0183297 |
| HDAC9 | histone deacetylase 9 | 0.0182289 |
| VEGFA | vascular endothelial growth factor A | 0.0181485 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0177176 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0173272 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.0172 |
| MYO1E | myosin IE | 0.0171363 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0168724 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.016657 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0166534 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0161777 |
| HMGA1 | high mobility group AT-hook 1 | 0.0160848 |
| BRD4 | bromodomain containing 4 | 0.0160469 |
| BMP6 | bone morphogenetic protein 6 | 0.0158015 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0156515 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0155656 |
| SRP54 | signal recognition particle 54kDa | 0.0154657 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0154494 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0153802 |
| MYO5B | myosin VB | 0.0152888 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0152582 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0152077 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0150067 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0149867 |
| NUP58 | nucleoporin 58 | 0.0149385 |
| HLA-A | major histocompatibility complex, class I, A | 0.0148862 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0148854 |
| GOLGA4 | golgin A4 | 0.0147659 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0147342 |
| ITSN2 | intersectin 2 | 0.014721 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0144847 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.145076 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0944816 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0806439 |
| H1-0 | H1.0 linker histone | -0.0745549 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0741261 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0604823 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.058407 |
| FAM13A | family with sequence similarity 13, member A | -0.0540435 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0493953 |
| CANX | calnexin | -0.0430552 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0429917 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0391174 |
| OGA | O-GlcNAcase | -0.0385346 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0383003 |
| AHNAK | AHNAK nucleoprotein | -0.0373969 |
| RPS24 | ribosomal protein S24 | -0.0370069 |
| GM2A | GM2 ganglioside activator | -0.0364149 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0350399 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0324438 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0323963 |
| CES1 | carboxylesterase 1 | -0.0315455 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.030467 |
| LAMB3 | laminin, beta 3 | -0.0303612 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0302923 |
| PTMA | prothymosin, alpha | -0.0297273 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0297235 |
| MORF4L2 | mortality factor 4 like 2 | -0.0294372 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0290506 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.028765 |
| MT2A | metallothionein 2A | -0.0281587 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0268896 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0261597 |
| RPS3 | ribosomal protein S3 | -0.025576 |
| TRIM56 | tripartite motif containing 56 | -0.0252986 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0251552 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0248257 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0247922 |
| IER3 | immediate early response 3 | -0.0247394 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0243345 |
| HDLBP | high density lipoprotein binding protein | -0.0242771 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0238652 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0236966 |
| CSTB | cystatin B (stefin B) | -0.023549 |
| ARF1 | ADP-ribosylation factor 1 | -0.02344 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0229577 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0229197 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0229011 |
| ABLIM1 | actin binding LIM protein 1 | -0.0226916 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0221178 |
| RPL26 | ribosomal protein L26 | -0.0217199 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0217077 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0216147 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0212852 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0211815 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0211084 |
| RPL4 | ribosomal protein L4 | -0.0211041 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0210301 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0209598 |
| HBP1 | HMG-box transcription factor 1 | -0.0209045 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0204943 |
| EMP1 | epithelial membrane protein 1 | -0.0200805 |
| ZNF292 | zinc finger protein 292 | -0.0198736 |
| SP100 | SP100 nuclear antigen | -0.0198114 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0197399 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0195368 |
| MT1X | metallothionein 1X | -0.019536 |
| MYOF | myoferlin | -0.0194797 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0192593 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.019054 |
| TMEM45B | transmembrane protein 45B | -0.019 |
| SEC24D | SEC24 family member D | -0.0189208 |
| KIAA1217 | KIAA1217 | -0.0188897 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.018807 |
| FRY | furry homolog (Drosophila) | -0.018523 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0183444 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0181366 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0178411 |
| CYTH1 | cytohesin 1 | -0.0178199 |
| HYOU1 | hypoxia up-regulated 1 | -0.0178146 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0177597 |
| SHTN1 | shootin 1 | -0.0175486 |
| RPL34 | ribosomal protein L34 | -0.0174329 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0173488 |
| ZBTB1 | zinc finger and BTB domain containing 1 | -0.0171801 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0170432 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0169781 |
| PRELID2 | PRELI domain containing 2 | -0.0169149 |
| RNF169 | ring finger protein 169 | -0.0168706 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0168352 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0164901 |
| METTL15 | methyltransferase like 15 | -0.0164787 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0164572 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0162994 |
| RPL23 | ribosomal protein L23 | -0.0157886 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0157705 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0156285 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0156197 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.015564 |
| SLC38A1 | solute carrier family 38, member 1 | -0.015401 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0153624 |
