| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Voriconazole_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.109031 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0956431 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0938323 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0929036 |
| ZNF292 | zinc finger protein 292 | 0.0833786 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0799916 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0752021 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0743895 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0699818 |
| OGA | O-GlcNAcase | 0.0621668 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0590118 |
| CDC73 | cell division cycle 73 | 0.0555395 |
| FOXO1 | forkhead box O1 | 0.0553698 |
| CUL3 | cullin 3 | 0.0548068 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0546716 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0542269 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0537889 |
| CCNI | cyclin I | 0.053687 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0533656 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0523368 |
| PDS5A | PDS5 cohesin associated factor A | 0.0514497 |
| MYO5B | myosin VB | 0.0511426 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0494279 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0479207 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0470156 |
| ECT2 | epithelial cell transforming 2 | 0.0468767 |
| SMYD3 | SET and MYND domain containing 3 | 0.0468426 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0468335 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0463986 |
| PCBP3 | poly(rC) binding protein 3 | 0.0459527 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.045169 |
| FTO | fat mass and obesity associated | 0.045162 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0446409 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0444417 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.0444151 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0443535 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0442508 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.043877 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0428625 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.042711 |
| PKN2 | protein kinase N2 | 0.0426161 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0425266 |
| TXNRD1 | thioredoxin reductase 1 | 0.0425221 |
| QKI | QKI, KH domain containing, RNA binding | 0.0423587 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0417488 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0417139 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0415662 |
| RORA | RAR-related orphan receptor A | 0.0415394 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0414831 |
| FMNL2 | formin-like 2 | 0.041304 |
| FNBP1L | formin binding protein 1-like | 0.040988 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.040948 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.040872 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0405248 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0402874 |
| FAM204A | family with sequence similarity 204, member A | 0.0396036 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.039505 |
| TOP1 | topoisomerase (DNA) I | 0.0391633 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0391062 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0389445 |
| PKM | pyruvate kinase, muscle | 0.0388987 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0388385 |
| SET | SET nuclear proto-oncogene | 0.0387524 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0383261 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0382725 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.038196 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0379216 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0375366 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0369908 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0363692 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0359491 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0358963 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0352216 |
| RPL11 | ribosomal protein L11 | 0.0350039 |
| PDE8A | phosphodiesterase 8A | 0.0348483 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0348036 |
| APP | amyloid beta (A4) precursor protein | 0.0345871 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0345367 |
| CCNL1 | cyclin L1 | 0.0344891 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0344041 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0338305 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0337036 |
| GLG1 | golgi glycoprotein 1 | 0.0334845 |
| DMXL1 | Dmx-like 1 | 0.0328423 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0322907 |
| MATR3 | matrin 3 | 0.0321933 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0318734 |
| SEPTIN10 | septin 10 | 0.0318568 |
| PGK1 | phosphoglycerate kinase 1 | 0.0318491 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0314787 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0311782 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0311209 |
| MED13L | mediator complex subunit 13-like | 0.0299272 |
| TPM3 | tropomyosin 3 | 0.0297958 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.029175 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0287942 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0287504 |
| NBAS | neuroblastoma amplified sequence | 0.0285327 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0283168 |
| TNPO1 | transportin 1 | 0.0280413 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.143564 |
| TMSB10 | thymosin beta 10 | -0.114862 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0988397 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0890919 |
| MUC16 | mucin 16, cell surface associated | -0.0847683 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.0813994 |
| KRT17 | keratin 17, type I | -0.080891 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0769856 |
| RPS25 | ribosomal protein S25 | -0.0731774 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0666585 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0660616 |
| RPS24 | ribosomal protein S24 | -0.0636687 |
| RPL26 | ribosomal protein L26 | -0.0578826 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0567757 |
| S100A9 | S100 calcium binding protein A9 | -0.0562059 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0554104 |
| RPLP0 | ribosomal protein, large, P0 | -0.0553898 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0546827 |
| RPL37A | ribosomal protein L37a | -0.0545854 |
| HLA-A | major histocompatibility complex, class I, A | -0.0537476 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0530869 |
| RPL15 | ribosomal protein L15 | -0.0530644 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0526915 |
| LAMB3 | laminin, beta 3 | -0.0518403 |
| MYO1E | myosin IE | -0.0508069 |
| S100A6 | S100 calcium binding protein A6 | -0.0503995 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0482396 |
| RPS12 | ribosomal protein S12 | -0.0468431 |
| TPM4 | tropomyosin 4 | -0.0440266 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0437731 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0421841 |
| MT2A | metallothionein 2A | -0.0420445 |
| RPL28 | ribosomal protein L28 | -0.0418033 |
| BPTF | bromodomain PHD finger transcription factor | -0.0417147 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0416104 |
| ENO1 | enolase 1, (alpha) | -0.0416077 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0413691 |
| RPL12 | ribosomal protein L12 | -0.0409578 |
| RPS6 | ribosomal protein S6 | -0.0400399 |
| ACTG1 | actin gamma 1 | -0.040038 |
| SVIL | supervillin | -0.0396947 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0395079 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0393501 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0392693 |
| CD44 | CD44 molecule (Indian blood group) | -0.0391683 |
| ANXA1 | annexin A1 | -0.038998 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0386466 |
| RPS27A | ribosomal protein S27a | -0.0382948 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0372113 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0367272 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0362051 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0361693 |
| UBC | ubiquitin C | -0.0358821 |
| OSMR | oncostatin M receptor | -0.0355307 |
| RPL35A | ribosomal protein L35a | -0.0354284 |
| HLA-B | major histocompatibility complex, class I, B | -0.0353859 |
| SLC38A1 | solute carrier family 38, member 1 | -0.034798 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0346483 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0345945 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0345502 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0343623 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0340371 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0335082 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.033285 |
| RPS16 | ribosomal protein S16 | -0.0327911 |
| ANXA2 | annexin A2 | -0.0327652 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0320705 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0313684 |
| RPL31 | ribosomal protein L31 | -0.0310374 |
| PDE10A | phosphodiesterase 10A | -0.0310232 |
| FAM13A | family with sequence similarity 13, member A | -0.0307202 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0307199 |
| RSF1 | remodeling and spacing factor 1 | -0.03066 |
| SEPTIN9 | septin 9 | -0.0306097 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0305183 |
| RPS20 | ribosomal protein S20 | -0.0302342 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.029733 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0296968 |
| POTEF | POTE ankyrin domain family, member F | -0.029211 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0289969 |
| TJP1 | tight junction protein 1 | -0.0289109 |
| RPS19 | ribosomal protein S19 | -0.0288419 |
| PRKCA | protein kinase C, alpha | -0.0288334 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0286872 |
| FTL | ferritin, light polypeptide | -0.0281666 |
| PTMA | prothymosin, alpha | -0.0276346 |
| CCND1 | cyclin D1 | -0.0276127 |
| SRPK2 | SRSF protein kinase 2 | -0.0269945 |
| RPS8 | ribosomal protein S8 | -0.0266974 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0262924 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0262847 |
| DSTN | destrin (actin depolymerizing factor) | -0.02578 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0255977 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0254673 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.025084 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.025062 |
| TES | testin LIM domain protein | -0.0250202 |
| RBM39 | RNA binding motif protein 39 | -0.0246889 |
| JMJD1C | jumonji domain containing 1C | -0.0246552 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0245723 |