| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.0792833 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0462826 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0354241 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0345598 |
| CCNL1 | cyclin L1 | 0.0344479 |
| TFG | TRK-fused gene | 0.0344111 |
| RNF145 | ring finger protein 145 | 0.0321213 |
| NCKAP1 | NCK-associated protein 1 | 0.0283682 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0271257 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0263804 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0262635 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0258447 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0248277 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0246202 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0239864 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0238104 |
| CDC73 | cell division cycle 73 | 0.0237027 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0231626 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0227133 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0225873 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.022272 |
| USP3 | ubiquitin specific peptidase 3 | 0.0215094 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0213606 |
| ANXA1 | annexin A1 | 0.0211991 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0194559 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0192503 |
| MATR3 | matrin 3 | 0.0190543 |
| POTEF | POTE ankyrin domain family, member F | 0.0190425 |
| PAPOLA | poly(A) polymerase alpha | 0.0190032 |
| PEG10 | paternally expressed 10 | 0.0188398 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0187309 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0185297 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0184684 |
| NUP58 | nucleoporin 58 | 0.018275 |
| WDR43 | WD repeat domain 43 | 0.0175532 |
| TXNRD1 | thioredoxin reductase 1 | 0.0174313 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0173255 |
| RYK | receptor-like tyrosine kinase | 0.0172341 |
| ANXA5 | annexin A5 | 0.017144 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.017031 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0168697 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0167716 |
| WDR36 | WD repeat domain 36 | 0.0160782 |
| OLA1 | Obg-like ATPase 1 | 0.0160727 |
| CD109 | CD109 molecule | 0.015971 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0156911 |
| ATP13A3 | ATPase type 13A3 | 0.0154317 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.015399 |
| ZNF292 | zinc finger protein 292 | 0.0152326 |
| RBM33 | RNA binding motif protein 33 | 0.0152187 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0150508 |
| IPO7 | importin 7 | 0.0148589 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0148372 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0147193 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0146299 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0144236 |
| ECT2 | epithelial cell transforming 2 | 0.0143899 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0142516 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0142428 |
| UBQLN1 | ubiquilin 1 | 0.0142271 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0141728 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0141174 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0139719 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0138704 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.013806 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0137468 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0136694 |
| SCEL | sciellin | 0.0134985 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0134532 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0134335 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0133927 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.013366 |
| FAM3C | family with sequence similarity 3, member C | 0.0133186 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0132687 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0131982 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0131859 |
| LRRC1 | leucine rich repeat containing 1 | 0.0131669 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0131377 |
| TMEM131L | transmembrane 131 like | 0.0130983 |
| HMGA1 | high mobility group AT-hook 1 | 0.013033 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0130191 |
| RHEB | Ras homolog enriched in brain | 0.0126742 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0126023 |
| CLINT1 | clathrin interactor 1 | 0.0125826 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0124458 |
| YTHDC1 | YTH domain containing 1 | 0.012418 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0124053 |
| NUP54 | nucleoporin 54kDa | 0.0122612 |
| SPAG9 | sperm associated antigen 9 | 0.0122243 |
| MSN | moesin | 0.0121066 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0120229 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0118787 |
| ZNF654 | zinc finger protein 654 | 0.0118319 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0117935 |
| QKI | QKI, KH domain containing, RNA binding | 0.0117079 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.011692 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0115986 |
| UPP1 | uridine phosphorylase 1 | 0.0114722 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0114576 |
| ARRDC3 | arrestin domain containing 3 | 0.0114382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.147316 |
| TMSB10 | thymosin beta 10 | -0.106637 |
| FTL | ferritin, light polypeptide | -0.10126 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0974793 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0956672 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0872155 |
| LAMB3 | laminin, beta 3 | -0.084967 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0820884 |
| ACTG1 | actin gamma 1 | -0.0783155 |
| FBXO32 | F-box protein 32 | -0.0739103 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0691164 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0677227 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0667086 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0649456 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0633269 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0611599 |
| TMSB4X | thymosin beta 4, X-linked | -0.0606599 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0579214 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.055061 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0539218 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0536885 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0534579 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0529014 |
| CSTB | cystatin B (stefin B) | -0.052279 |
| EFNA5 | ephrin-A5 | -0.049213 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0476294 |
| AHNAK | AHNAK nucleoprotein | -0.0473232 |
| RNF213 | ring finger protein 213 | -0.0462529 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0459115 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0440305 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0437981 |
| CD2AP | CD2-associated protein | -0.042995 |
| ENO1 | enolase 1, (alpha) | -0.0427312 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0422032 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0420793 |
| S100A6 | S100 calcium binding protein A6 | -0.0409001 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0401266 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0395147 |
| RRBP1 | ribosome binding protein 1 | -0.039471 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0393402 |
| LMNA | lamin A/C | -0.038853 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0381559 |
| HLA-B | major histocompatibility complex, class I, B | -0.0376928 |
| LMO7 | LIM domain 7 | -0.0376558 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0372663 |
| H1-0 | H1.0 linker histone | -0.0372336 |
| RAI14 | retinoic acid induced 14 | -0.037156 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0370599 |
| MX2 | MX dynamin-like GTPase 2 | -0.0370164 |
| MT2A | metallothionein 2A | -0.036777 |
| RPL34 | ribosomal protein L34 | -0.0366575 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0354807 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0349934 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0349922 |
| SQSTM1 | sequestosome 1 | -0.0347682 |
| HLA-A | major histocompatibility complex, class I, A | -0.0342005 |
| RPS19 | ribosomal protein S19 | -0.0339737 |
| MX1 | MX dynamin-like GTPase 1 | -0.0330321 |
| RPL35A | ribosomal protein L35a | -0.0328372 |
| RPLP1 | ribosomal protein, large, P1 | -0.0320712 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0313649 |
| GOLGB1 | golgin B1 | -0.0313547 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0311179 |
| SP100 | SP100 nuclear antigen | -0.0305637 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0302048 |
| RBM47 | RNA binding motif protein 47 | -0.0301635 |
| TPM4 | tropomyosin 4 | -0.0286242 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0283275 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.028224 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0282183 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0281738 |
| S100A10 | S100 calcium binding protein A10 | -0.0276987 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0276145 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0275987 |
| CAVIN1 | caveolae associated protein 1 | -0.0269543 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.026856 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0266157 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0265988 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0264671 |
| VIM | vimentin | -0.0263792 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0262799 |
| RPS29 | ribosomal protein S29 | -0.0262783 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0259045 |
| ETV6 | ets variant 6 | -0.0258673 |
| PLSCR1 | phospholipid scramblase 1 | -0.0257637 |
| FRMD5 | FERM domain containing 5 | -0.0256746 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0255193 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0254248 |
| TXNIP | thioredoxin interacting protein | -0.0253478 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0252793 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0249786 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0248799 |
| GNAS | GNAS complex locus | -0.0244259 |
| RIGI | RNA sensor RIG-I | -0.0244155 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.024254 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0242165 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0240865 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0237575 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0237304 |
| RPL23 | ribosomal protein L23 | -0.0237192 |
