| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Voriconazole perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Voriconazole_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0762187 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0472366 |
| MCL1 | myeloid cell leukemia 1 | 0.0432284 |
| EFNA5 | ephrin-A5 | 0.0431339 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0395597 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0377162 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0367309 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0349376 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0328871 |
| PGK1 | phosphoglycerate kinase 1 | 0.0296643 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0268327 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0266532 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0263588 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0254867 |
| PYGL | phosphorylase, glycogen, liver | 0.0251379 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0249458 |
| ATP13A3 | ATPase type 13A3 | 0.0248666 |
| PTEN | phosphatase and tensin homolog | 0.0246919 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0239338 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0238342 |
| MSN | moesin | 0.0232931 |
| NUP58 | nucleoporin 58 | 0.0231131 |
| RNF145 | ring finger protein 145 | 0.0227318 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0220681 |
| PRELID2 | PRELI domain containing 2 | 0.0215291 |
| NBAS | neuroblastoma amplified sequence | 0.0214484 |
| NGLY1 | N-glycanase 1 | 0.0214279 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0212662 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0211359 |
| NCKAP1 | NCK-associated protein 1 | 0.0206171 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0200053 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0197 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0194882 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0190258 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0189767 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0187426 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0186005 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0185155 |
| DNER | delta/notch-like EGF repeat containing | 0.0183763 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0181491 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.017863 |
| ARRDC3 | arrestin domain containing 3 | 0.0175809 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0175607 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0172503 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.017215 |
| HELZ | helicase with zinc finger | 0.0170078 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0169353 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0169306 |
| ANXA5 | annexin A5 | 0.0167891 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0167351 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0166369 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0165591 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.016084 |
| GRAMD1B | GRAM domain containing 1B | 0.0158152 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0157531 |
| CEP170 | centrosomal protein 170kDa | 0.0157252 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0157243 |
| POTEF | POTE ankyrin domain family, member F | 0.0155503 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0155246 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0154028 |
| ZNF292 | zinc finger protein 292 | 0.0153593 |
| TPM3 | tropomyosin 3 | 0.0153253 |
| NBEAL1 | neurobeachin-like 1 | 0.015313 |
| ANO6 | anoctamin 6 | 0.0152018 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0151338 |
| SP3 | Sp3 transcription factor | 0.0150625 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0150203 |
| GPC6 | glypican 6 | 0.0149088 |
| PTK2 | protein tyrosine kinase 2 | 0.0145663 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0144371 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0143318 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0142319 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0142125 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0141771 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0141546 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0140025 |
| CLTC | clathrin, heavy chain (Hc) | 0.0138334 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0137708 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0136511 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0136144 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0135922 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0135599 |
| FAM219A | family with sequence similarity 219, member A | 0.0135256 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0134595 |
| FLNB | filamin B, beta | 0.0133519 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0133415 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0132268 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0128711 |
| YEATS2 | YEATS domain containing 2 | 0.0124514 |
| VMP1 | vacuole membrane protein 1 | 0.0124485 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0122579 |
| SRPK2 | SRSF protein kinase 2 | 0.0122239 |
| TPD52 | tumor protein D52 | 0.0120841 |
| MFF | mitochondrial fission factor | 0.0120795 |
| FAT1 | FAT atypical cadherin 1 | 0.0120062 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0120007 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0117777 |
| ZNF638 | zinc finger protein 638 | 0.0116505 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0116463 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0116457 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.202907 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.19914 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.175897 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.152286 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.106703 |
| TMSB10 | thymosin beta 10 | -0.106355 |
| VIM | vimentin | -0.104005 |
| RPS6 | ribosomal protein S6 | -0.0980786 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0903884 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0878284 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0804068 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0775969 |
| SMYD3 | SET and MYND domain containing 3 | -0.0759144 |
| RPLP1 | ribosomal protein, large, P1 | -0.0746241 |
| PTMA | prothymosin, alpha | -0.0731357 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0707629 |
| GDA | guanine deaminase | -0.068569 |
| FTL | ferritin, light polypeptide | -0.068115 |
| COL5A2 | collagen, type V, alpha 2 | -0.0661578 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0660976 |
| RPS8 | ribosomal protein S8 | -0.0638174 |
| PDE10A | phosphodiesterase 10A | -0.062849 |
| RPL35A | ribosomal protein L35a | -0.0626166 |
| RPL12 | ribosomal protein L12 | -0.0619482 |
| RPL26 | ribosomal protein L26 | -0.061871 |
| ASPH | aspartate beta-hydroxylase | -0.0582868 |
| RPL23 | ribosomal protein L23 | -0.056209 |
| RPS24 | ribosomal protein S24 | -0.0560408 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0555095 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0533291 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0528067 |
| RPL19 | ribosomal protein L19 | -0.0515974 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0511154 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0507262 |
| VCL | vinculin | -0.0504213 |
| RPL31 | ribosomal protein L31 | -0.048704 |
| RPS19 | ribosomal protein S19 | -0.047803 |
| KYNU | kynureninase | -0.0474428 |
| RPL37A | ribosomal protein L37a | -0.0472662 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0466892 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0459203 |
| S100A6 | S100 calcium binding protein A6 | -0.0458314 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0445666 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.044449 |
| RPL34 | ribosomal protein L34 | -0.0444426 |
| RPS12 | ribosomal protein S12 | -0.0425943 |
| CANX | calnexin | -0.0414017 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0413981 |
| RPL7A | ribosomal protein L7a | -0.0404017 |
| CDH13 | cadherin 13 | -0.0401653 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0400058 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0396894 |
| GNAS | GNAS complex locus | -0.0391013 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0390072 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0385833 |
| RPL36A | ribosomal protein L36a | -0.0380385 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0379629 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0377731 |
| RPLP0 | ribosomal protein, large, P0 | -0.0377715 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0374831 |
| RPS3 | ribosomal protein S3 | -0.0367805 |
| RPS27A | ribosomal protein S27a | -0.0356101 |
| RPL9 | ribosomal protein L9 | -0.0353944 |
| RPLP2 | ribosomal protein, large, P2 | -0.035016 |
| ACTG1 | actin gamma 1 | -0.034781 |
| RPS29 | ribosomal protein S29 | -0.0346933 |
| RPL11 | ribosomal protein L11 | -0.0343637 |
| RPS25 | ribosomal protein S25 | -0.0342689 |
| S100A10 | S100 calcium binding protein A10 | -0.0342525 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0336425 |
| RPS14 | ribosomal protein S14 | -0.0329256 |
| RPL36 | ribosomal protein L36 | -0.0323705 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0321339 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0320779 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0318634 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0317183 |
| DST | dystonin | -0.0312984 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0312967 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0312235 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0306801 |
| RPS16 | ribosomal protein S16 | -0.0304927 |
| MT2A | metallothionein 2A | -0.0304781 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0304292 |
| MORF4L2 | mortality factor 4 like 2 | -0.0302646 |
| RPS27 | ribosomal protein S27 | -0.0301605 |
| RPL37 | ribosomal protein L37 | -0.0299544 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0299438 |
| RPS23 | ribosomal protein S23 | -0.0297635 |
| SQSTM1 | sequestosome 1 | -0.0295058 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0294335 |
| RPL38 | ribosomal protein L38 | -0.0292733 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0290977 |
| RPL35 | ribosomal protein L35 | -0.028664 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0285955 |
| RPS21 | ribosomal protein S21 | -0.027919 |
| INHBA | inhibin, beta A | -0.027378 |
| RTN1 | reticulon 1 | -0.0272715 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0270755 |
| HLA-B | major histocompatibility complex, class I, B | -0.0268508 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0268472 |
